Ghosal Lab
119 posts

Ghosal Lab
@GhosalLab
Genome instability in cancer and premature aging syndromes
Omaha, NE Se unió Haziran 2022
253 Siguiendo203 Seguidores
Ghosal Lab retuiteado

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Physics to John J. Hopfield and Geoffrey E. Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks.”

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Ghosal Lab retuiteado

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

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Ghosal Lab retuiteado

BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

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Excited to share the first article from our lab @NatImmunol nature.com/articles/s4159… Kudos to Drs. Abraham and Samaniego-Castruita for leading the studies. This work wouldn’t be possible without our amazing colleagues @NU_CDB, @immunology_nu, @LurieCancer, @NUFeinbergMed 1/n 🧵

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Ghosal Lab retuiteado

We recapitulated transcription-coupled repair in frog egg extracts and showed that STK19 couples stalled RNAPII to repair. Tour de force by @TychoMevissen (seeking PI positions, grab him if you can!), and key contribution from Lucas Farnung and team.
biorxiv.org/content/10.110…
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Most happy to share our work on characterising ARIP4 (aka RAD54L2) as a R-loop helicase that promotes AR-dependent (and most likely non-AR as well) transcription.
science.org/doi/10.1126/sc…
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Huge congratulations to Rahul Dogiparthi, a Bioinformatics and Systems Biology graduate student working in our lab at UNMC, for being selected by @ASH_hematology to receive the ASH Graduate Hematology Award (AGHA)! Very proud #ASHAwards
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👇👇 Congratulations 🙏🙏🙏 Dr. Oberley-Deegan!
unmc.edu/newsroom/2024/…
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Now online! APOBEC3A and APOBEC3B drive distinct mutational landscapes in tumors. We showed how A3A and A3B substrate preferences for different hairpin structures can be exploited to identify patients' tumors with mutations caused by either A3A or A3B. nature.com/articles/s4146…
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@nglab_malaria @GentleFlora @UNMC_PathMicro @unmc_research @UNMCCOM @UNMCCOPH @UNMC_GCHS @unmc Congratulations!!!!!
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My first R01! 🤩💵 9 months from the 3% score in June to official notification in January! Thank you @GentleFlora for guidance, friendship, and this #sash! #Mentorship matters @UNMC_PathMicro @unmc_research @UNMCCOM @UNMCCOPH @UNMC_GCHS @unmc


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Congratulations to Mrinal Srivastava (@MrinalS01 @TIFRH_buzz) on receiving the DBT-Wellcome Trust @India_Alliance Intermediate #Award for future investigations into mammalian replicative helicase activation.

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Ghosal Lab retuiteado

Check out our latest publication where we developed SEC-seq – a new technology that captures and measures single-cell protein secretion coupled with mRNA transcriptomes published in Nature Nanotechnology! nature.com/articles/s4156…
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Heartiest Congratulations to Dr. Halle Mallard. All the very best for your future endeavors. 👩🔬👩🎓 #UNMCGrad


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Ghosal Lab retuiteado

🚨Hot off the press! Check out my thesis work, out today in Molecular Cancer Research. 👩🏼🔬
USP1 Expression Driven by EWS::FLI1 Transcription Factor Stabilizes Survivin and Mitigates Replication Stress in Ewing Sarcoma
aacrjournals.org/mcr/article/21…
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