Rubens⚡️

Honored to present our work on frailty in CAR-T. Grateful to @QueraltSalas for pioneering this field and to the Clínic CAR-T team. #CART #Hematology #EBMT2026

We’ve learned how to deliver CAR-T. Now we need to learn how to live with its consequences.

This is not a limitation. It’s the natural evolution of a successful therapy.

CAR-T therapy changed outcomes. But we are now seeing a different layer of complexity. A recent Blood commentary shifts the focus: what happens after the initial response? 🧵

The future in #AML for older adults is not about choosing less. It’s about choosing better. More precise. More individualized. More honest.

And maybe the most important point: Not every patient wants the same thing. Some want maximum survival. Others prioritize quality of life. Both are valid.

Treating AML in older adults has changed. A lot. It’s no longer about age. It’s about biology, fitness, and goals. A quick thread on what actually matters now 🧵