Jef Akst

@ExcisionBio, whose HIV trial @biospace was watching, presented disappointing results this morning at #ASGCT2024: all three patients who came off conventional antiviral treatment experienced viral rebound. biospace.com/article/could-…

I'm looking for an editor to join our team here @biospace. If you are a journalist with an interest in the business of biopharma, let me know! biospace.com/minisites/bios…

FDA's Peter Marks once again from #ASGCT2024, this time on global regulatory convergence, saying that for rare diseases in particular, lack of regulatory standardization presents big challenges. @Slabodkin reporting for @BioSpace biospace.com/article/fda-s-… #ASGCT #ASGCT24

“$4.25 million!!!” That’s the email FDA’s Peter Marks said he received from Commissioner Robert Califf when Orchard revealed the price tag of its newly approved gene therapy Lenmeldy. Check out my @biospace recap of the #ASGCT2024 fireside chat: biospace.com/article/asgct2…

Leaving the morning session at #ASGCT2024 this morning and the Baltimore convention center is definitely filling up! #ASGCT #ASGCT24

"We’re not keeping score." -- FDA's Peter Marks on the success rate in accelerated approvals. But, he added, he's shooting for 90% or better. #ASGCT2024 #ASGCT24 #ASGCT @biospace

It's time! @TakedaPharma's Kristin Van Goor is sitting down with @US_FDA's Peter Marks to discuss regulatory issues in cell and gene therapy--topics that @biospace has covered in the past. I'm excited to hear what he has to say biospace.com/article/fda-s-… biospace.com/article/fda-br…

First day of #ASGCT24 is done. AAV manufacturing was a major theme with two long sessions already on it. And when I asked some folks in between sessions what they were interested in, that's what I heard about as well! biospace.com/article/aav-ma… #ASGCT #ASGCT2024 #AAVs @biospace

It's #ASGCT24 week! I made my first appearance on our podcast with @hmac8 and @Slabodkin talking about the cell and gene therapy updates we can expect to hear about in Baltimore. Be sure to tune in Wednesday when we'll be reporting from the conference. biospace.com/article/biospa…

The week of leaving my home-office for professional functions has begun. Yesterday I attended a @DCSWA professional development event at GWU. Next up, #ASGCT24 with @Slabodkin for @biospace

Next week at #ASGCT I will be attending a fireside chat on cell and gene therapy regulation with CBER Director Peter Marks and Takeda’s Kristin Van Goor. Read about their discussion and other #ASGCT24 news from BioSpace in our daily newsletter, Gene Pool. marketing.biospace.com/subscribe-to-g…

Less than a week until @Slabodkin and I meet up in Baltimore for the annual #ASGCT meeting. Cell and gene therapies are HOT right now, and I'm looking forward to learning what's new. Stay tuned to @BioSpace for #ASGCT24 coverage.

It's been a while since I've been to #AACR but I know that San Diego convention center well. I appreciate my colleagues at @biospace keeping me in the loop from afar this year. biospace.com/article/aacr-2…

Weight loss drugs are a big part of @biospace coverage these days. Check out our feature on the race to develop an oral GLP-1. Meanwhile, Medicare coverage of these therapies remains a point of discussion. biospace.com/article/will-o… biospace.com/article/the-ir…

Weight-loss drugs started as treatments for type 2 diabetes and are now moving into other related indications, which will affect coverage by Medicare and likely private insurers. @biospace #Wegovy #weightloss biospace.com/article/wegovy… biospace.com/article/medica…

Biden has made drug prices a cornerstone of his campaign, but what about Trump? @biospace Also, check out our BioPharm Exec newsletter, which today released a special edition on drug price reforms in the run-up to the 2024 presidential election. marketing.biospace.com/subscribe-to-b…

The #FDA's approval yesterday of #MadrigalPharmaceuticals' #Rezdiffra is the first-ever therapy for the treatment of noncirrhotic #nonalcoholicsteatohepatitis (NASH). Or was the approval for #metabolicdysfunctionassociatedsteatohepatitis (MASH)? biospace.com/article/nash-o… #liver

I'll admit I only learned of NASH (now MASH) after starting at @biospace last year, but exciting to see the FDA approve the first-ever therapy for the liver disease. @hmac8 has been watching all year for this one lnkd.in/e-PCK-nS lnkd.in/eU3yYhfk #fda #nash #mash

While #InVitroFertilization is back at Alabama #fertilityclinics, the #legal debate over #IVF continues across the U.S. and #drugmakers are forced to consider what effect a flurry of new political initiatives might have on the market. biospace.com/article/alabam… #frozenembryos

Today's episode of @biospace's The Weekly podcast drops in the midst of one of the busiest news times since I started here a year ago. From ever-hot weight-loss drugs to the fever pitch that is U.S. politics right now, great discussion, @Slabodkin @hmac8 biospace.com/article/the-sk…