SijbrenOttoLab

Selection for photocatalytic function through Darwinian evolution of synthetic self-replicators bit.ly/4oCH7C1

How to select primitive / synthetic replicators based their photocatalysis? Check out our manuscript just published in @NatureCatalysis : nature.com/articles/s4192… @KaiLiu125348 @Ottolab #OoL #Origins #Prebiotic #Evolution

Light-Mediated Interconversion between a Foldamer and a Self-Replicator | Journal of the American Chemical Society @LMU_Muenchen @StratinghInst @univgroningen #Foldamer #SelfReplicator #LightMediated #Interconversion pubs.acs.org/doi/10.1021/ja…

Simultaneous Formation of a Foldamer and a Self-Replicator by Out-of-Equilibrium Dynamic Covalent Chemistry | JACS @LMU_Muenchen @StratinghInst @univgroningen #Foldamer #SelfReplicator #OutofEquilibrium #Dynamic #Covalent #Chemistry pubs.acs.org/doi/10.1021/ja…

What can dissipative chemistry bring us? In our recently published paper, we demonstrate the emergence of mechanical function from disspative droplet systems. @NatureChemistry nature.com/articles/s4155…

Probe the non-enzymatic macrocyclization reaction of benzene-1,3-dithiol in the presence of peptide condensates by reactive Martini simulations, reported by @CG_Martini @OttoLab @csbrasnett nature.com/articles/s4200…

A little peak into last year's work with @Juntian74804617 and @Armin__Kiani in @OttoLab . You think our replicators are already complex enough? Then brace yourselves, Marcel has put 2-3 of them in competition and we had to make sense of their behaviour... chemrxiv.org/engage/chemrxi…

This study introduces a new mechanism that decreases error rates and corrects errors in synthetic self-replicating systems driven by self-assembly. @angew_chem #chemistry #Science #chemed #Technology #news @OttoLab @OmerMarkovitch onlinelibrary.wiley.com/doi/10.1002/an…

Generalist versus Specialist Self-Replicators (Sijbren Otto and co-workers) @seilenfranzli @Nitrogeno_N @GuilleMonrealS @OttoLab @StratinghInst onlinelibrary.wiley.com/doi/10.1002/ch…

Binding of Precursors to Replicator Assemblies Can Improve Replication Fidelity and Mediate Error Correction (Sijbren Otto and co-workers) #openaccess @OttoLab @OmerMarkovitch onlinelibrary.wiley.com/doi/10.1002/an…

Our newest paper is out!!! Here we show how a replicator system can correct errors during replication. Congrats @OmerMarkovitch and @Juntian74804617 🥳 Check it out: onlinelibrary.wiley.com/doi/10.1002/an…

Fancy doing some shiny new chemistry in a shiny new building? If so, come and join us @UoBChemistry 😀 We have fully funded PhD positions available working on…

Sijbren and Kayleigh were interviewed by @NEMOkennislink at the occasion of the 70th birthday of the famous Miller-Urey experiment. Check it out if you speak Dutch - or know how to use Google translate!

We have a PhD position on phosphate-driven non-equilibrium assemblies @ERC_Research funded at @FitFreiburg @UniFreiburg. Deadline for application is 15/01/24. More information can be found here: static1.squarespace.com/static/5fc3928… RT appreciated!

Can a purely chemical system reduces its #errors during #replication? And even "correct" them?. In this latest @ChemRxiv we are claiming YES to both questions! doi.org/10.26434/chemr… @OttoLab @Juntian74804617

@AlexBlokhuis @StratinghInst Thank you Alex!

@StratinghInst gefeliciteerd @OttoLab

@FeringaLab Thank you so much! Looks like there is some cyclic behaviour, one ERC every six years... Now it's clear why we didn't get it last year😏

Congratulations to Sijbren!!

More details about the proposal on the university website👇 rug.nl/research/strat…

BREAKING💥Ottogroup was awarded an ERC synergy grant, together with @AshkenasyLab and the groups of Eörs Szathmáry and Andrew Griffiths. Greatest thanks to all collaborators, it was a long and winding journey but it paid off!

More PhD and also post-doc positions will open - especially prospective post-docs are encouraged to get in touch with Sijbren soon. We offer high-quality research in a multidisciplinary field and (soon) in a brand-new building in Groningen!