Christian Schlein

103 posts

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Christian Schlein

Christian Schlein

@SchleinLab

Studying human genetics of lipid metabolism to develop novel innovative diagnostic and therapeutic approaches

Hamburg, GER Se unió Haziran 2022
193 Siguiendo225 Seguidores
Christian Schlein retuiteado
Borge G Nordestgaard
Borge G Nordestgaard@BNordestgaard·
Familial hypercholesterolemia was recorded in Danish registries since 1978, as the only country in the world. In both women and men in 1978 through 2021 age at death normalized but not age at coronary heart disease. Eur Heart J just published: academic.oup.com/eurheartj/adva…
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Ioannis Evangelakos, PhD
Ioannis Evangelakos, PhD@GEvangelakos·
Honored to have received the @AusMito travel award to represent @SchleinLab and present our work on mitochondrial fatty acid synthesis at @aussiemit 2024! Looking forward to this opportunity and meeting you all there! @TRR_BATenergy #mitochondria #lipids #brownfat
Mito Foundation@AusMito

🌟 Congrats to the recipients of the Mito Foundation's travel grants for @aussiemit 2024! These travel grants will help 7 researchers and health professionals attend AussieMit — Australia's largest conference related to mitochondrial biology and disease. aussiemit.com.au/awards/

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Christian Schlein retuiteado
Ioannis Evangelakos, PhD
Ioannis Evangelakos, PhD@GEvangelakos·
The @DDEA_Denmark Postdoctoral summit 2024 was a blast! Honored to receive the “Best Poster Award” and the “Second Best Poster Pitch Award” for our lab's recent collaborative work. @annawo13 @SchleinLab. Heartfelt thanks to the organizers and the committee for an incredible week!
Ioannis Evangelakos, PhD tweet mediaIoannis Evangelakos, PhD tweet media
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Christian Schlein retuiteado
Borge G Nordestgaard
Borge G Nordestgaard@BNordestgaard·
"Lipoprotein(a) and cardiovascular disease" review published today in The Lancet: 50 days' free access: authors.elsevier.com/a/1jlsNV-4XOtaS Please share and resend for others to download. Bottom line: measure Lp(a) in all once in a lifetime and stay tuned for coming Lp(a)-lowering therapy!
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Christian Schlein retuiteado
Alexander Bartelt
Alexander Bartelt@BarteltLab·
Today, we report that cholesterol-induced inflammation in adipocytes is under control of the Nfe2l1-ATF3 pathway. Proteasome-mediated proteostasis is vital to suppress insulin resistance and atherosclerosis in mice and is linked to obesity in humans. 👇 biorxiv.org/content/10.110…
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Christian Schlein retuiteado
KayLee Steiner, PhD
KayLee Steiner, PhD@steinerkaylee·
My first author paper from my thesis work has been uploaded to BioRxiv! We identified Mecr as important for T cell fitness in in vivo CRISPR screens. I have further worked with Mecr and am the first to show it regulates T cell function and metabolism. biorxiv.org/content/10.110…
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Christian Schlein
Christian Schlein@SchleinLab·
Good morning ☕🌞
Christian Schlein tweet media
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Björn Schumacher
Björn Schumacher@schumacherbj·
Preprints need to gain more visibility. With the current review process they are years ahead of the conventional publishing record. If you are a funding body, pay reviewers to evaluate preprints to make them fully eligible as track record.
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Martin Kircher
Martin Kircher@KircherLab·
Come and see posters of the lab at #ESHG2024 – Pia is presenting P20.013.B (award candidate) this afternoon and Mohan will present P16.084.D tomorrow afternoon. Very different work studying non-coding sequence effects with our collaborators at @NadavAhituv lab and @JShendure lab.
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Christian Schlein
Christian Schlein@SchleinLab·
Very much looking forward to meet you at the #ESHG2024 ! Please get in touch with us at Posters p05.013, p08.018 and p08.043 for some metabolic Research 🧑🏽‍🔬🔬🧪🧬
Christian Schlein tweet media
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Christian Schlein
Christian Schlein@SchleinLab·
Man stelle sich vor, dass man als Politiker nach einer Legislaturperiode entweder Minister ist oder gekündigt wird #WissZeitVG
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Christian Schlein retuiteado
Sam Tsimikas, MD
Sam Tsimikas, MD@Lpa_Doc·
This is a medical first- despite drug approvals for TG >500, none were shown to reduce pancreatitis. The Balance study required great science, a great drug, great study design, and great execution to succeed. Congrats to @ionispharma for 15 yrs of dedication and perseverance to help patients in need! nejm.org/doi/full/10.10…
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Christian Schlein
Christian Schlein@SchleinLab·
And now the manuscript got published at @NatureComms. What a nice start into 2024! Thanks to @annawo13 and her group as well as all other collaborateurs for this journey. #HappyNewYear @UKEHamburg nature.com/articles/s4146…
Christian Schlein@SchleinLab

What determines the composition of complex lipids and how can we use it therapeutically? In the preprint of Worthmann et al., we investigated a patient with a de novo variant in FASN which has a strong impact on PUFA enrichment. @annawo13 1/12 researchsquare.com/article/rs-100…

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@AusMito @aussiemit @TRR_BATenergy @DDEA_Denmark @annawo13 @cnag_eu @Solve_RD @KircherLab