Tim

@astralopithekos @TheMomoftheHour I can confirm this was how it was in Alberta. You had to argue with the gatekeepers who would then decide whether they would book you an appointment. Most of the time they refused and suggested mRNA. And then like you said, CDN gov't stopped ordering saying no one wanted it.

@TheMomoftheHour not sure about alberta, but that's how it was in lots of places! and then the next year they were like hmmm seems not many people got it, i guess no one was interested. 😡

so do we think Novavax will be coming back to canada this year? has anyone heard anything?

@anarchotadigism False. The Dec expiry have expired. But Feb expiry still available. As you said, pharmacist didnt want to look into it further, so did no research and guessed, and gave wrong info.

@anti_gyro_ @DonEford Pfizer is not allowed to use it in their covid vax according to the agreement. Pfizer most likely using it in their pneumonia vax, or one of their many other vax.

@DonEford If you had to guess, would this go into their future Covid vaccines or mostly for other conditions?

Pfizer has entered into a NONEXCLUSIVE deal with Novavax to run tests with Matrix-M. This is what we've been advocating for: to see Matrix-M incorporated into other vaccines, because it could make every other vaccine we use so much better. This means we did it, we won. It's rare to see a win lately, so take it for what it is and chalk up the "W" on the board.

@ginni_bb @DonEford The Pfizer deal has nothing to do with Novavax covid vax. Pfizer is using it for their pneumonia vax. Sanofi owns all rights to Novavax covid vax and has better distribution than Pfizer. Just need the long term mRNA contracts to run out, then Sanofi can use their connections.

@DonEford I really hope this comes off - since there doesn’t seem to be any prospect of novavax in the UK (unless you have news Don?) improving Pfizer might be our best hope for better ongoing Covid cover (although I’d still really like novavax).

@KllN349312 @EndemicPrepared i used gemini, maybe it gave me wrong info.

@Tim_Jamesc @EndemicPrepared I did.

Will this give aussies some chance of Novavax access?

@KllN349312 @EndemicPrepared no, you can check ai

@Tim_Jamesc @EndemicPrepared Do you have a link to that application?

@KllN349312 @EndemicPrepared Sanofi submitted for fast track approval late 2025 when they took over most Novavax markets and authorization. The next TGA meeting is early Feb 2026 and Novavax approval should be on agenda.

@Tim_Jamesc @EndemicPrepared What? There is zero evidence for availability of Novavax in Australia as far as I know. Where have you heard that it will be available?

@KllN349312 @EndemicPrepared AI suggested it based on novavax refund to Australia if not approved/available by March 2026. If approved novavax keeps the $97 million deposit and will deliver the doses. At $60 estimated/dose = 1.5 million doses.

@Tim_Jamesc @EndemicPrepared Where have you read about the 1.5 million doses part?

@michaelzlin This not true, although protein is better. They are using Matrix-M (broad utility) in their other products, most likely their pneumonia vax. Pfizer doesn't say anything about Covid vax. They are still selling Biontech covid vax because they are market leader, no reason to pivot.

Well that's interesting, Pfizer has licensed Novavax's adjuvant. That suggests they're realizing that protein vaccines are an easier sell than RNA biospace.com/deals/pfizer-m…

@equusjf @Biff234523 Pfizer has nothing to do with Novavax covid vax. Sanofi owns rights to the Novavax covid vax. Matrix-M is component of Novavax covid vax, and Pfizer only has a license to use Matrix-M in their products, most likely their Pneumonia vax. Novavax still owns everything.

@Biff234523 I hope Pfizer doesn’t simply bury Novavax

📢Huge news from Novavax today, Pfizer just entered into a licensing agreement which will allow them to use Novavax’s Matrix-M adjuvant in their products. This is similar to the agreement that was signed with Sanofi back in 2024, minus the Nuvaxovid commercialization. Novavax has been talking a lot about this for the past few months, noting that they had signed 2 MTAs (material transfer agreements) with top-10 pharma companies, which essentially just means that they were allowed to investigate the use of Matrix-M. Now, we have confirmation that one of those companies is Pfizer, and that they’re taking the next step to potentially including Matrix-M in their vaccines. Idk about you…but after 4 years of fighting this battle, what I’m hearing here is that Pfizer is finally admitting: 1. They weren’t able to get rid of Novavax as a company or a product…although they certainly tried…so they’re deciding not to ignore the elephant in the room any longer. 2. The elephant in the room is that their COVID-19 product is worse than Nuvaxovid…because why on earth would you need to invest in part of Nuvaxovid if that wasn’t the case? But that’s fine…we can put all of that in the past. This is legitimately really great news, and Matrix-M will hopefully be able to save more lives here as part of Pfizer’s portfolio, just like it’s been doing in Nuvaxovid and in the R21 Malaria vaccine in Africa. We can all finally get to work on advancing vaccines with next-generation adjuvants that actually work, and restoring the trust of the American people @Novavax @pfizer @sanofi @SecKennedy @US_FDA @FDACBER @DrMakaryFDA @CDCgov @RWMaloneMD @KMilhoanMDPhD

@GreeneWendy @Biff234523 Sanofi owns rights to the Novavax covid vax. This Pfizer deal has nothing to do with Covid vax, they are licensing Matrix-M adjuvant. Matrix-M can be applied to many vaccines, treatments. It is used in the most effective Malaria vax. Pfizer will use it in their Pneumonia vax.

@Biff234523 I guess I was wondering about the vax itself (rather than the adjuvant) since one is based on mRNA technology & the other on the classic protein model, which Novavax fans say is better. I'm willing to stand corrected. I just want progress!

Any insight into this? Is it good news or not?

@SarahMcGinger @Biff234523 Sanofi is trying to make Nuvaxovid available in Canada for Spring 2026. If they can't manage to do it because of economics/gov't, they will definitely try to make it available Fall 2026 since Sanofi controls everything for covid vax now, while last year were still transitioning.

@Biff234523 I’m not sure I understand. Would that mean Pfizer will make a non-MRNA vaccine, or incorporate Novavax’s vaccine into their existing MRNA?

@SarahMcGinger @Biff234523 The Matrix-M adjuvant has broad uses, oncology, vaccines, mRNA. Matrix-M is jewel of Novavax, the Covid vaccine is a single product. Matrix-M is in most effective Malaria vaccine and is the reason for the high effectiveness, already been given to 25 million African children.

@SarahMcGinger @Biff234523 Pfizer is licensing the Matrix-M adjuvant from Novavax. It is totally unrelated to Novavax covid vax, Nuvaxovid. It is rumored that Pfizer will be using the Matrix-M in their Pneumonia Vaccine. Novavax already licensed the covid vax to Sanofi, who is now responsible for it.

@AarynKowalchuk @we_are_ssd Even if someone did buy Novavax, Sanofi owns the rights to the Novavax Covid vax and plans to keep distributing it.

@we_are_ssd Did they buy Novavax?

Novavax is so good that Pfizer wants to license it lol reuters.com/business/healt…

@EndemicPrepared Since Novavax already approved by US FDA, and Europe EMA, and all other countries they applied to, it is very likely Australia will also approve, especially now that Sanofi is handling everything.

@EndemicPrepared Sanofi is now in charge and carries the most weight with regulators because they have most of the flu vax market. Their plan is to offer both flu and covid vax to doctor's offices and is likely TGA will approve. Novavax carried little weight, while Sanofi is the largest player.

@EndemicPrepared Sanofi/Novavax submitted the latest approval request to TGA, the Australian health regulator late 2025 for fast track approval. TGA are expected to review it in Early Feb. and approve it within 6 days after the meeting, this seems to meet the timelines for Australia vax season.