Vedanta Biosciences

433 posts

Vedanta Biosciences

Vedanta Biosciences

@VedantaBio

Cambridge, MA Se unió Aralık 2015
105 Siguiendo1.6K Seguidores
Vedanta Biosciences retuiteado
CARB-X
CARB-X@CARB_X·
Thank you to @CARB_X developers, partners, and investors who gathered in Vienna, Austria on April 10 for CARB-X's annual Investor Day! More than 20 developers in advanced product stages presented to downstream investors interested in supporting antimicrobial products.
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Vedanta Biosciences retuiteado
Bernat Olle 🇺🇦
Bernat Olle 🇺🇦@bernatolle·
This analysis show the positive impact of VE303 treatment on the levels of antibiotic resistance genes in the gut microbiomes of patients enrolled in the Ph2 CONSORTIUM study, revealing associations between higher dosage and colonization of VE303 strains with lower levels of ARGs
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Vedanta Biosciences retuiteado
Bernat Olle 🇺🇦
Bernat Olle 🇺🇦@bernatolle·
@themissingmenon will be giving the late-breaking oral presentation this Friday in LA as part of Infectious Diseases Week (IDWeek) 2024
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Vedanta Biosciences retuiteado
Greg Medlock
Greg Medlock@MedlockGreg·
We are recruiting a Bioinformatician to join our Systems Biology team at Vedanta. Come work with us to advance defined bacterial consortia as a new drug modality! job-boards.greenhouse.io/vedantabioscie…
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Vedanta Biosciences retuiteado
Xavier Lab
Xavier Lab@TheXavierLab·
Exciting collab with @Honda1Kenya’s lab, out today in @Nature: A set of microbial strains taken from a human faecal donor can decolonize multidrug-resistant Enterobacteriaceae in the gut, including species associated with #IBD. (1/3) nature.com/articles/s4158…
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Vedanta Biosciences retuiteado
Bernat Olle 🇺🇦
Bernat Olle 🇺🇦@bernatolle·
We did not have a blueprint for how to get an LBP ready for a registrational study. In the last couple of years, the process development, analytical development, manufacturing, and quality teams @vedantabio worked tirelessly navigating uncharted waters /7
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Vedanta Biosciences retuiteado
Bernat Olle 🇺🇦
Bernat Olle 🇺🇦@bernatolle·
The Phase 3 study, RESTORATiVE303, is now underway in the US. We plan to expand enrollment to include >20 countries. It is a registrational study designed to support a BLA submission /6
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Vedanta Biosciences retuiteado
Bernat Olle 🇺🇦
Bernat Olle 🇺🇦@bernatolle·
In the Phase 2 CONSORTIUM Study, VE303 demonstrated strong evidence of efficacy and a good safety profile, and so the VE303 high dose has been advanced to Phase 3 development /5
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Vedanta Biosciences retuiteado
Bernat Olle 🇺🇦
Bernat Olle 🇺🇦@bernatolle·
VE303 is a potential first-in-class Live Biotherapeutic Product consisting of an 8-strain defined bacterial consortium. "Defined" means the product has a specific, known composition of bacterial strains. Each capsule contains the same strains, at a consistent dose /4
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Vedanta Biosciences retuiteado
Bernat Olle 🇺🇦
Bernat Olle 🇺🇦@bernatolle·
Fecal Microbiota Products are made from donor feces. We believe this has inherent limitations around commercial scalability, risk of pathogen transfer, and batch-to-batch variability. We hope to advance the field with DEFINED products which obviate the need for donors /3
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Vedanta Biosciences retuiteado
Bernat Olle 🇺🇦
Bernat Olle 🇺🇦@bernatolle·
FDA has approved two Fecal Microbiota Products for rCDI, which provide patients access to an alternative to unregulated FMT fda.gov/vaccines-blood… /2
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