Bhaskar Bhushan

1K posts

Bhaskar Bhushan

Bhaskar Bhushan

@BhaskarScience

All opinions my own, yes, even that one.

Inscrit le Nisan 2013
721 Abonnements149 Abonnés
Joe Abercrombie
Joe Abercrombie@LordGrimdark·
The awe-inspiring window display at ⁦@GigameshTienda⁩ in Barcelona. I’ll be signing here from 5pm today.
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Kawamura Group
Kawamura Group@KawamuraGroup·
🌟After an incredible 10 years, we bid a fond farewell to @DrRomanBelle as he embarks on an exciting new chapter! Roman’s contributions to our chemical biology research, his scientific insight and dedication have left a lasting mark on our work. 🌟
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Ambika Bhagi-Damodaran
Ambika Bhagi-Damodaran@AmbikaBhagi·
A day after #MothersDay, I am excited to announce that I have been promoted to Associate Professor with tenure @UMNChemistry. We did it despite (and with) these two monkeys and a once-in-a-lifetime pandemic. So thankful to my village and hope to pay it forward. I am so lucky!!!
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Yuan Yang
Yuan Yang@YuanfenYang·
Joint statement from myself and Abtisam Mohamed MP.
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Kawamura Group
Kawamura Group@KawamuraGroup·
In our chem bio research groups, we are committed to fostering an inclusive environment where everyone can thrive and make a difference. Special thanks to all the women in the Kawamura Research Group and @mcallister_lab for their contributions to the field of science! #IDWGS2025
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Airfinity
Airfinity@Airfinity·
The cost of #Wegovy to prevent one stroke in the US is double what’s paid by Britain’s health service, reveals new analysis by Airfinity. Read our feature in @Bloomberg to find out more. bloomberg.com/news/articles/…
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Airfinity
Airfinity@Airfinity·
Join our @ScienceUnga Webinar: Data for Pandemic Preparedness: New approaches for medical countermeasure (MCM) delivery Live next Wednesday 18th September 2024, 3pm ET/ 8pm BST. Register for free through the UNGA Science Summit online portal below. sciencesummitunga.vfairs.com/en/registratio…
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Keriann Backus
Keriann Backus@Keribackus·
Bit of good news to end the week---and a big big thank you to everyone who helped make this possible, especially all members of our lab past and present, mentors, letter writers, colleagues, friends+family.
UCLA Biological Chemistry@BC_UCLA

We are thrilled to announce that @Keribackus has been promoted to the rank of Associate Professor with tenure! We congratulate Keri on this well-deserved achievement and look forward to her lab continuing to make impactful discoveries! 👏👏🎉🍾

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Oxfordshire Compass
Oxfordshire Compass@Compass_Oxon·
Compass Oxon had a fabulous day yesterday campaigning in Banbury for voters to support @UKLabour candidate, @SEANLWOODCOCK. Bravo and a huge thank you to everyone involved. #WinAsOne
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Jacob Trueman
Jacob Trueman@TheJacobTrueman·
suck it tories and tory supporters me and sadiq and some other guy
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Bhaskar Bhushan
Bhaskar Bhushan@BhaskarScience·
@skathire Probably, given the association between obesity and HFpEF, although the negative RELIVE-HF trial presented at a late breaking session yesterday showed that even a regimen that increases mortality risk in HFpEF could lead to increased KCCQ!
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Sek Kathiresan MD
Sek Kathiresan MD@skathire·
Maybe the eternal search for an effective HFpEF med is finally over? Amazing! Another win for GLP-1 receptor agonists, now in heart failure with preserved ejection fraction (HFpEF)
NEJM@NEJM

Among patients with obesity-related heart failure with preserved ejection fraction & type 2 diabetes, semaglutide produced greater reductions in symptoms, physical limitations & body weight than placebo at 1 year. Full STEP-HFpEF DM trial results: nej.md/3TPKpUC #ACC24

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Airfinity
Airfinity@Airfinity·
This weekend, Airfinity is at #ACC24, @ACCinTouch's annual scientific conference. Get in touch via obesity@airfinity.com if you would like to get a free briefing with our Chief Medical Officer @hsillesen and Senior Director @BhaskarScience
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Sek Kathiresan MD
Sek Kathiresan MD@skathire·
Today, @VerveTx is announcing updates to our PCSK9 program: 1. voluntarily pausing enrollment in the Heart-1 trail of VERVE-101 2. prioritizing clinical development of VERVE-102 which uses a different LNP delivery system 3. announcing clinical trial application have been cleared in U.K. & Canada for Heart-2 trial of VERVE-102 4. expect initiation of Heart-2 trial this quarter Details: 1. 13 patients dosed so far in Heart-1 trial, 6 at 0.45 mg/kg dose 2. Efficacy: up to 73% reduction in LDL-C and durability out to 270 days after single treatment 3. However, at potentially therapeutic doses, seeing laboratory abnormalities 4. last patient dosed at 0.45 mg/kg experienced a Grade 3 drug-induced transient increase in serum alanine aminotransferase as well as a serious adverse event of Grade 3 drug-induced thrombocytopenia (a drop in the platelet count) 5. Lab changes transient, reversible, asymptomatic 6. Nevertheless, have elected to pause enrollment to investigate in order understand mechanism, if means to mitigate 7. Regulators informed; IND, CTAs for Heart-1 trial remain active 8. We believe lab safety findings attributable to lipid nanoparticle delivery system 9. For now, prioritizing development of VERVE-102 10. VERVE-102 uses an LNP with an ionizable lipid that has been tested in third-party clinical trials and well-tolerated 11. VERVE-102 also adds a GalNAc liver-targeting ligand 12. Expect to start Heart-2 trial of VERVE-102 in 2Q '24 Link to PR: ir.vervetx.com/news-releases/…
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Jacob Trueman
Jacob Trueman@TheJacobTrueman·
Sat on the tube across from Larry Dean and there’s just no way I’m gonna have the guts to say hello I’m a fan i’m literally shaking, such a wimp
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Bhaskar Bhushan
Bhaskar Bhushan@BhaskarScience·
Had an excellent time at the @BriTANicK show yesterday at the @sohotheatre! An absolutely fantastically crafted show, go see them if you get the chance! Also, bonus run-in with @TheJacobTrueman of the Fratocrats :)
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Emily Flashman
Emily Flashman@emily_flashman·
UK plant science twitter, can you help? Is anyone growing whole cell Arabidopsis thaliana cultures and would be happy to share some with us? Ours sadly died but we need some for more experiments! Many thanks :-)
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