Chekan Lab

Out now in @Chem_CP , we collaborate with @piel_lab to discover a prenyltransferase+terpene cyclase fusion enzyme that modifies Trp residues in RiPPs to yield complex steroid-like scaffolds! Congrats to @HubrichFlorian, @sanathrajkk0 for leading this!🎉authors.elsevier.com/c/1jjdi8jWHELG…

The #BJOC thematic issue on Young investigators in natural products chemistry, biosynthesis, and enzymology is now complete! 31 contributions from young investigators around the world! Check it out! @BeilsteinInst beilstein-journals.org/bjoc/series/129

Thrilled to share our work on the new plant Cu enzymes, BpCs! We offer mechanistic insights and structural recommendations for advancing BpC research. Thanks to @jess_panch for inviting us to publish in @TrendsChemistry ! 🌿🧬🧪 authors.elsevier.com/a/1jzvn9CpcYaQ…

When the standard approaches didn't work, @Chad46971777 came up with a new one to solve a synthetic challenge that @YeWangum was having. Mix in @AzamHussai70792 and the following @J_A_C_S paper was the result. @NarayanLab @MichiganChem @UMLifeSciences #biocatalysis

We studied rSAM, HtkB catalyze a His-to-Lys crosslink, and revealed conserved active site residues that influence substrate specificity. Brandon Morinaka Lab | RSC Chem Biol doi.org/10.1039/D4CB00…

Come join our awesome team @uncg_chem @UNCG. We are seeking a new colleague to teach organic chemistry to our absolutely amazing students! Please rt 🙏🧪⚗️🌞

Priority date to apply is Oct 15 @Chemjobber

Our dept of Chem&Biochem is hiring an Asst Prof in the areas of Inorganic/Bioinorganic Chem. We are an R2 that combines exceptional research with mentorship and teaching of a diverse student population. Come join our fantastic community! #chemjobs spartantalent.uncg.edu/postings/30223

Calling all Inorganic Chemists. Join our amazing department with a tenure track Assistant Professor position. I love @uncg_chem. Great colleagues, remarkable students, low cost of living. Check us out! spartantalent.uncg.edu/postings/30223

My amazing department, @bio_uncg, is hiring an Assistant Professor in Genetics/Cell Biology! Since starting @UNCG, I've felt incredibly supported and can't speak highly enough of this department! Please retweet and share with colleagues! spartantalent.uncg.edu/postings/30224

Delighted that a collaboration with @Nairlab_UIUC is now online @nchembio Nucleobases are common in biology but not in peptides. In this work, a nucleobase-peptide hybrid is generated from a ribosomal precursor peptide via YcaO domain protein catalysis. nature.com/articles/s4158…

Never underestimate a diiron enzyme. Congrats @sanjoyadak90 for bringing the nitrile synthase AetD to life with @Drennan_lab, Maria-Eirini Pandelia, and Ken Houk labs. Published today @NatureChemistry nature.com/articles/s4155…

Congrats to @HubrichFlorian & @sanathrajkk0 for this exciting story finally being published. Thanks for the fruitful collaboration with @chekanlab. If you are interested in the chemical space of #RiPP #biosynthetic #enyzmes and #isoprenoids, click here: sciencedirect.com/science/articl…

@BradMoore_SIO @Chem_CP @piel_lab @HubrichFlorian @sanathrajkk0 @moorelabsio Thanks Brad!

@ChekanLab @Chem_CP @piel_lab @HubrichFlorian @sanathrajkk0 Congrats Jon, Joern and your teams! Such a cool and important story. Fun seeing former @moorelabsio postdocs collaborating so well together

Out now in @Chem_CP , we collaborate with @piel_lab to discover a prenyltransferase+terpene cyclase fusion enzyme that modifies Trp residues in RiPPs to yield complex steroid-like scaffolds! Congrats to @HubrichFlorian, @sanathrajkk0 for leading this!🎉authors.elsevier.com/c/1jjdi8jWHELG…

@tyler_alsup_ @Chem_CP @piel_lab @HubrichFlorian @sanathrajkk0 Thanks! I feel you have heard about this project for 2 years. Glad that it is finally out!

@ChekanLab @Chem_CP @piel_lab @HubrichFlorian @sanathrajkk0 So cool! Congrats all!

It was great working with you on this exciting project!

So excited that @uncg_chem has been awarded the 2024 @UNCG_CAS Diversity Award. Join us in person or virtually, September 10th at 3:30 EDT, to share ideas about inclusiveness in science. DM me for a link cas.uncg.edu/event/deans-di…

@The_Tidge_Lab Hopefully it helped! 😂

@ChekanLab I used to show this to my BioChem class every year while they filled out the course evaluations!!

Thrilled to have accomplished a major career goal nearly 15 years in the making today! I showed my biochem class the 1971 stanford protein synthesis video. youtube.com/watch?v=u9dhO0…

@shaunmckinnie I only ever hear the words GTP and 50S ribosome as someone from the 70s yelling it.

@ChekanLab Iconic! GTP!!! tRNA!!!

@SmithLabUMBC It's the best! Amazing what they knew about the process 50+ years ago.