Lachmann_Lab
217 posts

Lachmann_Lab
@LachmannLab
The lab combines basic biology of stem cells and macrophages with translational approaches of cell therapy to develop novel forms of treatments







Out in @CellCellPress today! We describe the first humans with inherited, complete FLT3L deficiency. Despite a lack of most dendritic cells, they reached adulthood. See the thread below for the main highlights of our paper. cell.com/cell/fulltext/…


We are sorry to share the news that Dr. Connie Eaves has passed away. Dr. Eaves was a leader & trailblazer in the #stemcell & #cancer fields, & her impact has been felt around the world. To her family, colleagues, friends, & the people she mentored, we extend our condolences.

Differential impact of #high-#salt levels in vitro and in vivo on #macrophage core functions #MolBiolRep @lab_mass @Wjkkol @LabSchultze @UniBonn @DZNE_en #Efferocytosis; #Inflammation; #Phagocytosis; #Salt #sensing shorturl.at/kCGSY









1/ We are excited to report the discovery and mechanistic exploration of human AR complete CCR2 deficiency in @CellCellPress. Surprisingly, CCR2 deficiency underlies two narrow phenotypes: progressive polycystic lung disease and mycobacterial disease (sciencedirect.com/science/articl…).

So good when you see a former graduate of @CReM_Boston spreading the Open Source gospel! Way to go @killian_hurley Lab @RCSI_Irl ! Keep sharing! #opensourcerules! #itsthecells! #helpisontheway! stemcellres.biomedcentral.com/articles/10.11…



New #JITC article: Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia bit.ly/479s0XI @LachmannLab @ShifaaAbdin





