



Dimitris Patseas
293 posts

@DimitrisBio
PhD student | Immune dysregulation in Chronic Liver Disease | @imperialcollege















🎯JOB ALERT🚨| Research Assistant or Associate in Computational Immunology | We are seeking to recruit a scientist with immunology and bioinformatics (scRNA-seq) background. Join our team at @imperialcollege |🧪🥼👉triantafylloulab.com Information: imperial.ac.uk/jobs/search-jo…









🔵The second Keynote of #ECI2024 was an EXTRAORDINARY session led by Prof. Tak Mak👏👏, provided an in-depth exploration of the complex interplay between metabolism, neural regulation, immunity, and cancer. 🔍 Here’s some key points: 🔑New targets in oncology: balancing the fire and water. 🔬TET2 and IDH2 mutations in hematopoietic cells induce T cell lymphoma (AITL). 🧬Metabolic adaptation, affects DNA repair and genomic instability results in immune activation affecting immnotherapy responses. 👉Acetylcholine produced by T cells controls liver cancer. 💥The neuroimmune circuit activates cholinergenic lymphocytes in cancer. 💡Serum choline levels predicts improved progression free survival in patiente receiving immunotherapy. #CancerResearch #Immunology #Metabolism #Neuroscience #KeynoteLecture












New #JITC article: Therapeutic inhibition of monocyte recruitment prevents checkpoint inhibitor-induced hepatitis bit.ly/4aHQvxf @TriantafyllouE_ @CathrinLC @TurajlicLab