Manoli Lab

Prairie voles that don't have oxytocin receptors still bond and parent, as we (@UCSFPsychiatry and @UCSF), @BalesLab & @Shah_Laboratory show in @NeuroCellPress authors.elsevier.com/a/1gUwg3BtfH1Z…

@AnneZMurphy @lyoun03 My deepest condolences to you, your family, and the long and great extended family that he built.

It is with an unbelievably heavy heart that I write that my husband, best friend, and partner in crime for 20 years, Larry Young, passed away unexpectedly. I will share details regarding a memorial service once I know something. Please share with those who knew Larry @lyoun03

📢🧠 Applications for the 2023 One Mind Rising Star Awards are open! Learn more about and how to apply for our $300K grants supporting early-career neuroscience and psychiatry investigators who are working to accelerate #mentalhealth breakthroughs: onemind.org/rising-star-aw…

High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways dlvr.it/Sl4Dmb

Attn FEMALE ‘MENTORS’: Young Female mice exposed to Odor of older female mice live longer. elifesciences.org/digests/84060/…

Exciting new research update from 2018 One Mind @JanssenUS Rising Star Awardee Dr. Susanne Ahmari sheds light on brain activity in #BingeEating disorder and uncovers a potential treatment target. Congrats @ahmari_lab! Read more: pubmed.ncbi.nlm.nih.gov/36682623/

Our latest! Led by @nathanCSharris & Sam Bates we ask: How do experiences modify neuronal gene expression to drive plasticity? We find that multiple stimulus features can be encoded in the gene expression program of a single sensory neuron.. 1/13 biorxiv.org/content/10.110…

1/ 🧵I’m excited to announce new work from the Clowney lab, led by @mariaahmedch. Maria re-engineered the neuronal constituents and connectivity of an “expansion layer” to ask how quantitative properties of circuit wiring structure perception. biorxiv.org/content/10.110…

New science from Shea Lab: "Selective deletion of Methyl CpG binding protein 2 from parvalbumin interneurons in the auditory cortex delays the onset of maternal retrieval in mice" by @dcarrot2 with a major assist from @PagliaroAlexa biorxiv.org/content/10.110…

#Oxytocin—a hormone long considered essential to social bonding—may not be as critical as originally thought. “While oxytocin has been considered ‘Love Potion #9,’ it seems that potions 1 thru 8 might be sufficient,” Dr. Devanand Manoli (@LabManoli) says. ucsfh.org/3HE7FA7

.@labManoli is calling the role of #oxytocin into question. In a new study with @BalesLab and @Shah_Laboratory, they showed prairie voles without oxytocin receptors can bond, give birth, and feed their young ucsfpsy.ch/3HEFIs8 @UCSF #UCSFWeill

We're very excited and happy that this collaboration is now out in the world! thanks @LabManoli @Shah_Laboratory

@ForrestDRogers_ Really proud of the work we did with you and @BalesLab @Shah_Laboratory !

Congratulations, Dev, Nirao, Maricruz, Yichao, Srini, and the team on this epoch-making paper! 🎉🎉🎉 @LabManoli @NiraoShah @amaricruz3_a @YichaoWei sciencedirect.com/science/articl…

Thought-provoking research from 2021 One Mind @JanssenUS Rising Star Awardee Dr. Devanand Manoli suggests that it may be time to reevaluate long-held hypotheses about the role of oxytocin in some forms of social attachment. Congrats, @LabManoli! Read more: sciencedirect.com/science/articl…

Oxytocin receptor is not required for social attachment in prairie voles cell.com/neuron/fulltex… The tragedy of Science-the slaying of a beautiful hypothesis by an ugly fact (Huxley?). Been on the other side and know how much it stinks-but this is why we do science!

@wmkenkel @UCSFPsychiatry @UCSF @BalesLab @Shah_Laboratory @NeuroCellPress Will be very interesting to see what the biology ends up being!

@LabManoli @UCSFPsychiatry @UCSF @BalesLab @Shah_Laboratory @NeuroCellPress Super interesting. Specific to lactation: I wonder if voles' approach to nursing differs from classic milk letdown. I was always told voles do more of a steady dribble than other mammals -maybe due to pups' milk teeth?

Prairie voles that don't have oxytocin receptors still bond and parent, as we (@UCSFPsychiatry and @UCSF), @BalesLab & @Shah_Laboratory show in @NeuroCellPress authors.elsevier.com/a/1gUwg3BtfH1Z…

@jjennychenn @UCSFPsychiatry @UCSF @BalesLab @Shah_Laboratory @NeuroCellPress Great question! Work in progress

@LabManoli @UCSFPsychiatry @UCSF @BalesLab @Shah_Laboratory @NeuroCellPress Cool paper! Are there any V1aR null voles and do they bond/parent?

Prairie voles can form pair-bonds and rear pups without oxytocin receptor signaling, contrary to decades of research stating otherwise. Read more in @NeuroCellPress: cell.com/neuron/fulltex… @LabManoli @Shah_Laboratory

Excited to share my lab’s new paper out today @CellCellPress. "Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity" Congratulations to this amazing team of scientists. cell.com/cell/fulltext/…