Nystul Lab
18 posts

Nystul Lab
@NystulLab
Nystul lab @UCSF exploring cell fate decisions in the #Drosophila follicle cell lineage. Opinions are our own and not the views of our employer.
San Francisco, CA शामिल हुए Ekim 2019
144 फ़ॉलोइंग201 फ़ॉलोवर्स

So excited about our new study on the role of intracellular pH in the regulation of cell fate in the mouse intestinal epithelium! rdcu.be/df8CE It was a fun collaboration between 3 labs that built on our fly work—in both systems, increased pH helps specify cell fate.
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The deadline to sign up for the 2022 UCSF Diversity Supplement Matchmaking Event is today! If you qualify for an NIH DS and are looking for a full time paid research position at UCSF, sign up at justice.ucsf.edu by 11:59pm tonight!
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So excited to see our new study come out in @Dev_journal. It was a fun journey, with many contributors along the way, that led us to unravel distinct roles for a new gene in Drosophila ovarian follicle cell differentiation. doi.org/10.1242/dev.19…
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Looking for paid full-time postbac research opportunities at UCSF? Check our our new program at propel.ucsf.edu and info about our recruiting event at justice.ucsf.edu. For more info, come to one of the Q&As in the next few weeks: tiny.ucsf.edu/MME22
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The Nystul Lab is recruiting for a new postdoc! We are looking for a creative and talented person interested in exploring the mechanics of epithelial cell fate decisions in Drosophila. Apply at nystullab.uscf.edu. I will also be at the #Dros21 networking session on 3/26
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Nystul Lab रीट्वीट किया

Interested in doing research after graduation? Register for the "matchmaking event", where you can meet UCSF PIs looking for post-bac researchers.
Participants must be US Citizen/Permanent Resident and belong to an underrepresented group in sciences.
eventbrite.com/e/nih-diversit…
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So proud to see our Drosophila ovary cell atlas paper out today! rdcu.be/b9PrV. It was a multi-lab collaboration to describe cellular diversity in the ovary and we discovered that niche cells can convert to stem cells upon starvation. Thanks to all who contributed!
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Our review on signal transduction in the follicle stem cell lineage is available on line now.
You can access it for free with this link until April 9th.
authors.elsevier.com/a/1aboi7tYJFd7… Happy reading!
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Nystul Lab रीट्वीट किया

In the beginning we learn that nurse cells provides nutrients and everything else to the oocyte, but who would have thought that two of these nurse cells provides almos everything, even its nuclear content to the oocytes.... ooooooohhhhh disq.us/t/3ljg77y
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So exciting to see this very cool new technique published. I think this is going to open up a lot of new avenues of research! Congrats O'Brien lab! dx.plos.org/10.1371/journa…
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Exciting developments in fly ovary cell atlases that we're way behind in tweeting about: Beautiful studies from the Lehmann lab genesdev.cshlp.org/cgi/content/lo… and the Deng lab biorxiv.org/content/10.110…. Also, check out the community effort: flybase.org/commentaries/2…
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Nystul Lab रीट्वीट किया

Well, that's pretty crazy.
Nurse cell nuclei enter the oocyte and this seems to be important for normal egg development.
"Fusion of #Drosophila oocytes with specified germline sister cells"
biorxiv.org/content/10.110…
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Check out our latest study doi.org/10.7554/eLife.… We kept an open mind but all our data led back to the idea that germaria typically have only 2 FSCs. The original Margolis study continues to stand the test of time! There's more variability than we originally thought, though.
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Check out our cell atlas of the Drosophila ovary, posted on @biorxivpreprint. We provide transcriptional profiles for many cell types, new markers for FSCs and other cell types, and lineage tracing showing unexpected cellular plasticity during starvation. biorxiv.org/content/10.110…
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