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The real McCoy: an unbiased and experimental, i.e. "real" approach to target ligandability, discerning between functional/allosteric binders and identification of ligand hotspots.
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Accelero Biostructures
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Accelero Biostructures
@AcceleroB
Protein Crystallography-driven Fragment- and Structure-Based Drug Discovery
Bergabung Şubat 2019
98 Mengikuti46 Pengikut
Delighted to speak on “Rapid hits, hotspots and hit-to-lead by crystallographic library screening: case studies in targeting proteins for novel drug discovery” from our ABS-OneStep platform in Melbourne at IUCr2023.
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Great to be going back to Asilomar for the West Coast meeting (West Coast Structural Biology Workshop, formerly, West Coast Protein Crystallography Workshop).
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MAD/SAD protein X-ray crystallography methods developed by Wayne were key in enabling rapid and large scale protein structures determined in structural genomics
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We are delighted to announce that Wayne A. Hendrickson @Columbia has won the @IUCr 13th Ewald Prize for his exceptional contribution to structural biology including the development of MAD/SAD methods and crystallographic theory. Read more at iucr.org/iucr/ewald-pri…
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