Fischbach Lab

Preprint alert! Excited to share our new manuscript from @CornellBME @GarrettBeeghly examining how the size of fat cells, or adipocytes, impacts breast cancer risk. We found that larger adipocytes promote aggressive behavior in tumor cells. 1/5 biorxiv.org/content/10.110…

As an undergraduate researcher, Yiwei Yan ’25 studied how breast cancer cell growth is regulated in bone by investigating how bone mineral content and tumor-secreted factors influence the growth of mesenchymal stem cells.

Hypertrophic adipocytes increase extracellular vesicle-mediated lipid release and reprogram breast cancer cell metabolism biorxiv.org/content/10.110… #biorxiv_cellbio

Ultimately, our findings suggest that larger adipocytes are a distinct cell population within adipose tissue and increase lipid transfer to invading cancer cells. As a result, we propose that adipocyte size could be a valuable prognostic biomarker for breast cancer patients. 5/5

In a published cohort of mastectomy patients, we found that average adipocyte size predicted dyslipidemia and circulating triglycerides more than BMI. These results suggest that altered lipid release by larger adipocytes may also have implications for whole body metabolism. 4/5

Preprint alert! Excited to share our new manuscript from @CornellBME @GarrettBeeghly examining how the size of fat cells, or adipocytes, impacts breast cancer risk. We found that larger adipocytes promote aggressive behavior in tumor cells. 1/5 biorxiv.org/content/10.110…

Thanks @FischbachLab for accepting our invitation and giving an excellent keynote to kick off the 2025 GRS Physical Science of Cancer 🙏! #POC_GRC_2025 grc.org/physical-scien…

Check out our latest publication in @Biomaterials_ on how mineralized scaffolds alter the microenvironmental composition of pre-clinical tumor models: sciencedirect.com/science/articl…

Feeling extremely grateful to have completed my PhD with so much support from @CornellBME, @FischbachLab, and my fantastic advisor. I can't imagine the past six years anywhere else. Excited to see what is next! #PhDone

Congratulations @GarrettBeeghly on a fantastic defense and significantly advancing our understanding of adipocytes and their role in cancer! Well done Dr. B! @CornellBME @FischbachLab

Come join us!

Couldn’t have asked for a more perfect day for @FischbachLab apple picking @CornellBME

Going to the @BMESociety Annual Meeting in Baltimore next week? Check out these @FischbachLab presentations and posters! And stop by the @CornellBME booth to learn more about our graduate MEng and PhD programs

Thank you to @LammerdingLab and @FischbachLab bakers and everyone else who made the fundraiser our most successful year yet! We raised over $1100 for @CancerResource. Make sure to check out all the amazing work the CRC does at crcfl.net

Made chocolate caneles for our annual @CancerCornell bake sale fundraiser for the @CancerResource Center of the Finger Lakes! Stop by Weill Hall today for some freshly baked goods and to support a great cause 👨‍🍳

Ever had Gochujang cookies? Come and get some (or other delicious items) today at bake sale in Weill Hall ⁦@CornellBME⁩ in support of ⁦@CancerResource⁩ organized by ⁦@FischbachLab⁩ ⁦⁦@LammerdingLab⁩

Members of the ⁦@FischbachLab⁩ and the ⁦@LammerdingLab⁩ out in force at today’s Walkathon and 5K run in support of the ⁦@CancerResource⁩

We're Hiring! Seeking a Tenure Track Faculty Position in Biomedical Engineering, @Cornell @CornellEng @CornellBME #BME. Learn more, apply: academicjobsonline.org/ajo/jobs/28277

And we got to try the Gewürztraminer harvest straight from the vine at HJW!

We got to enjoy the beautiful weather over the weekend as part of the inaugural @FischbachLab wine tour. There’s lots to do and see in the Finger Lakes besides science! Apple picking is up next…