Gothelf lab

The work by Mads K. Skaanning and other members of our team on the self-assembly of (L)-acyclic threoninol nucleic acids into ultrasmall wireframe nanostructures was recently published in JACS. pubs.acs.org/doi/10.1021/ja…, @iNANO_AarhusUni, @Chemistry_AU

Jakob Smidt from our lab visited Lennart Lykke @novonordisk during his PhD studies and the collaboration resulted in a method to conjugate GLP1 to any phosphate in siRNA. See the resulting paper in Nucleic Acids Research. academic.oup.com/nar/advance-ar…. @iNANO_AarhusUni, @Chemistry_AU

Reversible protection of DNA origami by a cationic disulfide polymer that is cleaved inside cells is reported in Small by Sarah Youssef @SarahYo45655307 and other members of our team. @iNANO_AarhusUni, @Chemistry, onlinelibrary.wiley.com/doi/10.1002/sm…

Triplex DNA blossoms on the front cover of Advanced Materials featuring our Triplex Origami methodology. The cover art is entirely made out of real folded paper! By postdoc @MinkieWinky and PhD student Emily Tsang. Read the article here: onlinelibrary.wiley.com/doi/full/10.10…

@baukevon @iNANO_AarhusUni @Chemistry Thank you! I am also looking forward to the IUPAC/CHAINS 2023 conference.

@GothelfLab @iNANO_AarhusUni @Chemistry Very nice work! Wonder what other use for TFOs can be achieved. Looking forward to your lecture at the IUPAC|CHAINS2023 conference!

So far, DNA nanotech has almost exclusively relied on Watson-Crick base interactions. In our new paper in Advanced Materials, we show that Hoogsteen interactions have the same potential to organize double-stranded DNA. @iNANO_AarhusUni, @Chemistry, onlinelibrary.wiley.com/doi/epdf/10.10…

@DNA_Nanotech @iNANO_AarhusUni @Chemistry Thank you, Yoel!

@GothelfLab @iNANO_AarhusUni @Chemistry Congratulations! 🍾🎊🎉🎈

@iNANO_AarhusUni @AarhusUni @novonordiskfond @AarhusUni_int @MolBiolAU @roskildeuni @ETH_en @kjems_rgen @CellPAT_AU We are looking forward to take part in the development of new RNA therapeutics in this center.

Helping patients with metabolic diseases like diabetes and atherosclerosis etc.!🤞💊 This is the goal of a new research team. Prof Jørgen Kjems opens centre for #RNAmedicine research at @AarhusUni with generous support from @novonordiskfond. #RNA #medicine inano.au.dk/about/news-eve…

Congratulations to Minke Nijenhuis for winning the excellent student or post presentation award at FNANO2023, where she presented our work on triplex origami and we also had a reunion with two former GothelfLab members Zhao Zhang and Abhichart Krissanaprasit.

"Automated Solid-Phase Oligo(disulfide) Synthesis" is now online in Angewandte Chemie and special thanks to Martin Frandsen and Alexander Sandahl who have led this work. onlinelibrary.wiley.com/doi/epdf/10.10…

Happy to share our recent preprint on folding double-stranded DNA into designed shapes with triplex-forming oligonucleotides: chemrxiv.org/engage/chemrxi…

Our latest paper on bioconjugation, that was made in collaboration with Novo Nordisk A/S, was selected for editors favourite recet articles over at OBC. pubs.rsc.org/en/content/art… #Gothelflab #realtimechem #NovoNordisk #ChangingDiabetes

Line and Malthe from the Gothelf Lab at #AarhusUni has spent the last 3 months in Copenhagen at the #BioInnovation Institute. If you're curious to hear what they've learned, you can watch at 15.30 using this link: youtube.com/watch?v=v0Oyku… #Science #chemistry #bioscience

Professor Kurt Gothelf ⁦@GothelfLab⁩: The DNA origami method will undoubtedly influence development of new medicine ⁦@AaltoUniversity⁩ ⁦@nantech2019⁩ aalto.fi/en/news/profes…

A close collaboration between #NovoNordisk and our lab at #iNANO has resulted in a recent publication in #AngewandteChemie. #Science #Chemistry #biotech For more information and link to the article, please visit: inano.au.dk/about/news-eve…

PAPER: Researchers from the Gothelf lab has recently published a mini review in #ChemBioChem on how to design probes for affinity guided protein conjugation. #Chemistry onlinelibrary.wiley.com/doi/10.1002/cb…

PhD student Mette Riis Bakke from the @GothelfLab will be having her qualifying exam this Wednesday. phd.scitech.au.dk/currently/show…

Our most recent review about "Chemistries for DNA Nanotechnology" pubs.acs.org/doi/10.1021/ac…

Quantitative Detection of Digoxin in Plasma Using Small‐Molecule Immunoassay in a Recyclable Gravity‐Driven Microfluidic Chip - Li - - Advanced Science - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10…

Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab‐DNA conjugates - Gothelf - - ChemBioChem - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.100…