H.S. Shafaat

We are moving! I'll miss all the wonderful people at OSU and am so fortunate to have spent the last 10 years here. We are excited to start the next chapter of the Shafaat Group at @uclachem in July! chemistry.ucla.edu/news/welcoming…

Celebrating the wonderful visit from Madeline Ho from the Hoffman and Chen labs at Northwestern to discuss their beautiful ENDOR EPR spectroscopy studies on non-symmetrical [Fe-S] clusters. We enjoyed your talk, chatting with the group, and sharing our science.

Congratulations to Henry & all-- major thanks to the PNNL & OSU teams! This was a true collaborative effort that we're excited to see out. Give it a read if you're interested in paramagnetic Ni NMR, regular protein NMR, or catalyst dynamics-- there's even some machine learning!

From lab days to beach nights and gift-exchange chaos (featuring one cat supervisor 🐈), the Shafaat Group & friends are wishing you warmth, joy, and a happy holiday season! ✨🎄💫

Check out our POTW! Thanks, Henry, for highlighting this study showing that ENDOR S/N can be significantly improved through frequency multiplexing—simultaneously pulsing multiple nuclear frequencies and decoding them via Hadamard transformation. tinyurl.com/ur73256y

Calling all #Bioinorganic folks in SoCal! The 2025 SoCal Bioinorganic Symposium is at UCLA on Nov 8th, 2025. The abstract deadline for a talk or poster has been extended to Nov 1st, 2025. We are looking forward to seeing you all! tinyurl.com/yrwnjaz7

Thrilled to share the first paper from our group at UCLA, online today in Science: “Biocatalytic, Asymmetric Radical Hydrogenation of Unactivated Alkenes” @uclachem @ScienceMagazine science.org/doi/10.1126/sc…

Calling all #Bioinorganic folks in Southern California! Join us for the 2025 SoCal Bioinorganic Symposium at UCLA on November 8, 2025. Submit your abstract for a poster or talk by October 25 → tinyurl.com/yrwnjaz7

We are thrilled to welcome Prof. Kate Buettner (@gettysburg ) to our group for her sabbatical! She'll be helping us explore exciting new frontiers in metalloproteins– we can’t wait to see where this journey takes us!

Excited to showcase our group’s work at the 21st ICBIC in Long Beach! Stop by our posters and join us for the research talks!

Celebrating the wonderful visit from @MatthewGaynes from the @ChristiansonLab to discuss their beautiful Terpenoid cyclases reactivity and structural characterization using X-ray and Cryo-EM techniques. We enjoyed your talk, chatting with the group, and sharing your science.

Diverse lineages and adaptations of oxygen-adapted hydrogenases sciencedirect.com/science/articl…

Curious how enzymes adapt to oxygen? Our new collaborative review with the @Rhys_G and @Greeninglab groups explores how oxygen-tolerant [NiFe]-hydrogenases evolved across microbes to thrive in aerobic environments revealing innovative metabolic changes in Earth’s redox landscape.

Shoutout to our outstanding undergrads — Sofia, Megan, Ryan, and Isaiah — for showcasing their research at the UCLA Chemistry Undergraduate Research Symposium!  Great work all around! #UCLAChem

We are delighted to announce that Professor Christopher Chang (Princeton) has won the 2025 Chemical Science Lectureship! rsc.li/chemsci-lectur… Chris will deliver his Lectureship at the 2025 #ChemSciSymposium on 18-19 November in London, UK: rsc.li/chemscisymp2025

Check out our POTW! Thanks, James, for highlighting this study using ultrahigh-throughput FACS to screen 10⁹ variants/day! Engineered enzymes showed up to 16× improved activity on highly stable N-aryl amide & carbamate bonds. bit.ly/4mAn4nB

Just saying… You will be mind blown! Join us!

Curious how energy research ties into the origins of life? Join us tonight in L.A. for a pint and a science talk by Hannah—you’ll leave with your mind blown and your glass empty!  🧠🍻 bit.ly/4dtGqXt

Check out our POTW! Thanks, Henry, for highlighting this study, which shows that aerolysin nanopore sensing can distinguish cis/trans isomers of proline-containing peptides at the single-molecule level, opening doors for structural analysis and PPIase inhibitor screening. 🔗