Chris Jackson

202 posts

Chris Jackson

Chris Jackson

@cjackstats

Senior Investigator Statistician at the MRC Biostatistics Unit, University of Cambridge. Also at https://t.co/J9glTsCC5M https://t.co/mpsAfcK08O

Cambridge, England Bergabung Kasım 2017
130 Mengikuti459 Pengikut
Chris Jackson
Chris Jackson@cjackstats·
The package should also be useful as an easy way to fit a flexible Bayesian survival model in general, even if you don't need extrapolation. It is inspired a lot by rstanarm , and tweaks the model in arxiv.org/abs/2002.09633 in various ways to facilitate extrapolation.
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Chris Jackson
Chris Jackson@cjackstats·
Hoping people will try it and use it. Please feed back, in particular if you would like to use it, but something about it looks too hard! The idea is to make principled methods easily accessible.
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Chris Jackson
Chris Jackson@cjackstats·
You can (a) build in multiple data sources (e.g. trial, registry, population, elicited...) in a general format (b) fit models with a single command, (c) output results with a single command, in a friendly tidy format.
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Chris Jackson
Chris Jackson@cjackstats·
Announcing a new paper "survextrap: a package for flexible and transparent survival extrapolation" doi.org/10.1186/s12874… . Proud of this, as I've been interested in the problem for many years, but only recently had time to get stuck into a solution. Tweet summary below.
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Chris Jackson
Chris Jackson@cjackstats·
So the model output is a posterior which says what your data says, and represents uncertainty properly if there is no long-term data.
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Chris Jackson
Chris Jackson@cjackstats·
The paper introduces an R package chjackson.github.io/survextrap/ that does all this. It uses a flexible Bayesian model, fitted with mc-stan.org. The "hazard" of death is allowed to vary over time using a spline, and can vary smoothly outside the data.
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Chris Jackson
Chris Jackson@cjackstats·
Ideal tool would be able to (1) combine several data sources (2) fit it all well (3) acknowledge uncertainty where data are weak. And not forgetting: (4) be easy to use!
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Chris Jackson
Chris Jackson@cjackstats·
Health policy decisions often involve "extrapolating" short term data from trials. To do this properly, we have to build in long term information. There's been lots of methods papers on the topic, but no ideal tool.
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Chris Jackson me-retweet
RJB Goudie
RJB Goudie@rjbgoudie·
3yr postdoc job opportunity @MRC_BSU @Cambridge_Uni in Bayesian methodology Potential topics/directions: computational methods for data integration/Markov melding; methodology for prior specification; methods for multi-stream EHR data Closes 6 Nov jobs.cam.ac.uk/job/43238/
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Chris Jackson
Chris Jackson@cjackstats·
(A department neighbouring the one that I work in, I meant to say)
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Chris Jackson
Chris Jackson@cjackstats·
If you like multistate / survival modelling you may be interested in this position jobs.cam.ac.uk/job/41966/ collaborating with some good people in a neighbouring department.
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Chris Jackson
Chris Jackson@cjackstats·
Coming to the end of an enjoyable three days of #RSS2023Conf . Too much good science and people to pick highlights, just generally feeling that stats and statisticians are alright!
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