Nick

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Nick

Nick

@docdocrace

liker of brains 🧠 , birds 🦜, and being outside 🏔️

Bergabung Ocak 2017
1.9K Mengikuti820 Pengikut
Nick
Nick@docdocrace·
We are recruiting another brain injury doc at UC Davis in Sacramento, CA! Exciting stuff Please reach out if interested to learn more. Come join us in NorCal 🤙 More info here: recruit.ucdavis.edu/JPF07198
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Veera Rajagopal 
Veera Rajagopal @doctorveera·
A mind-blowing paper has come out today in @Nature In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" (science.org/doi/10.1126/sc…). Today, a group of scientists from Indiana University reports how that minimal genome evolved over 2000 generations in comparison to the non-minimal genome. The authors found that even when you reduce a bacterial genome to its absolute minimum where every nucleotide matters, the genome undergoes mutational events generation after generation as much as the non-minimal genome. One simply cannot stop the evolution. Just over 300 days of evolution (equivalent to 40,000 years in humans) the minimal cell has gained everything it lacked in fitness on day one in comparison to the non-minimal cell. When comparing the evolved traits between the minimal and non-minimal cells, the scientists found something striking. The evolutionary process increased the cell size of non-minimal cells but not that of the minimal cell. But that is not the striking part. The scientists were able to identify the key mutation that resulted in cell size evolution. And it turned out that the mutation that helped the non-minimal cells to grow bigger is the same that helped the minimal cells to stay smaller. Growing bigger had a survival advantage for non-minimal cells and not growing bigger had a survival advantage for minimal cells. So, the mutation had a context-dependent effect. This just demonstrates that the evolutionary effects on traits have no absolute direction. All that matter is what is beneficial for the organism's survival. The conclusion of the paper is metaphorically a quote from the Jurassic Park movie: “Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way". (scienmag.com/artificial-cel…) nature.com/articles/s4158…
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Nick
Nick@docdocrace·
@DanDaneshvar Kudos to you and the whole team for this fantastic work. Glad this hypothesis is gaining traction in larger studies! Count me among the believers in cumulative energy, symptoms or not
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Dan Daneshvar, MD, PhD
Dan Daneshvar, MD, PhD@DanDaneshvar·
In the largest study of CTE to date: concussion does not cause CTE The predicted total force to the head that athletes experienced over their lifetime was the best predictor of who had CTE, and how severe it was
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Kathryn Hyzak, PhD
Kathryn Hyzak, PhD@DrKateHyzak·
Happy #BrainInjury (BI) Awareness Month! This fact sheet helps ⬆️awareness of BI in the U.S. Two points I’ll highlight: 1️⃣We don’t have accurate prevalence estimates of BI b/c not everyone seeks tx, or BI is improperly identified 2️⃣Overdoses=BI! Substance tx providers take note
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Nick
Nick@docdocrace·
@gbosslet burning bay leaves can be useful for banishing rituals 👹. true story also 🔥 addition to tomato-based eggs in purgatory or poached cod
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Gabriel Bosslet
Gabriel Bosslet@gbosslet·
Bay leaves don’t do jack shit The bay leaf industry has fooled us all to putting a stale frond in our food that we have to take out before serving They are geniuses I won’t be convinced otherwise
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Nick
Nick@docdocrace·
@av0gadra another one of their greatest hits is making people in pain go get a med every single day. medicine has comedy figured out
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v@av0qt·
one of medicine’s favorite jokes is making people with ADHD pick up a medication every 30 days
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Nick
Nick@docdocrace·
#SCIIncubate is wonderful - a fantastic program/experience! @NeuroVigor Therapeutics benefited tremendously from the program last year Highly recommend for anyone trying to commercialize technology geared toward helping individuals living with #SCI Application details below👇
Praxis Spinal Cord Institute@praxis_sci

Applications for Praxis SCI Incubate 2023 are open! Do you have an early prototype #SpinalCordInjury innovation that could impact quality of life for those living with #SCI? Praxis #SCIIncubate program can help expand your reach. Deadline to apply Nov 20: praxisinstitute.org/commercializat…

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Nick
Nick@docdocrace·
Some colleagues/friends are organizing a donation to PPAF (matched 1:1 through June 30) to support reproductive/abortion rights. Funds are not earmarked. If so inclined, we welcome your support. Funds go directly to PPAF from this GoFundMe gofundme.com/f/donate-to-pr…
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dinosaur
dinosaur@dinosaurcouch·
bonus panel
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dinosaur
dinosaur@dinosaurcouch·
on a date.
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Neuro Vigor Therapeutics
Neuro Vigor Therapeutics@NeuroVigor·
Neuro Vigor is seeking preclinical and clinical collaborators interested in studying the impact of reactive aldehyde species (RAS) in various disease states. Learn more from our website: nvtherapeutics.com
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