AV Washington

109 posts

AV Washington

@AVWashingtonLab

Dr. Washington’s lab studies the #TLT-1 #platelet receptor which influences #hemostasis and inflammation mediated by platelets and the immune system.

Oakland University 参加日 Eylül 2022

154 フォロー中169 フォロワー

AV Washington@AVWashingtonLab·23 Haz

A special opportunity at #ISTH2025 to celebrate the power of scientific lineage - introducing Dan McViker to his “scientific grandchildren” in platelet research. Science is as much about innovation as it is about connection — across generations, disciplines, and borders.

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AV Washington@AVWashingtonLab·26 May

Still in Kraków, presenting at the GENOMICA Student Conference of Genetics. A vibrant community of undergraduate & graduate researchers. I was truly impressed by quality of their work, especially the posters—hearing students explain their work was energizing.

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AV Washington@AVWashingtonLab·23 May

Today in Kraków, I shared a proposed mechanism of TLT-1 function linking in vitro findings with in vivo data at Instytut Farmakologii im. Jerzego Maja, Polish Academy of Science. Excited about the potential for collaborations ahead. #ScienceCollaboration #TLT1

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AV Washington@AVWashingtonLab·14 Mar

Thankful for the opportunity to present at the at #HTRS2025 this week on how TLT-1 nucleates clot formation in the presence of low levels of #platelet agonist. This mechanism could open new avenues for therapeutic strategies in coagulation disorders.

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AV Washington@AVWashingtonLab·22 Şub

Shade Onunkun, Nana Boateng & Dr. Lauver from MSU Department of Pharmacology & Toxicology joined Dr. Avery’s graduate seminar at @oaklandu to present their latest research findings. Great presentations, sparking insightful discussions and fostering collaboration!

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AV Washington@AVWashingtonLab·4 Ara

The OU @oaklandu University Career & Life Design Center & Biojourneys initiative teamed up with Endo Pharmaceuticals to help students explore their personalized career pathways! Glad to be part of this collaboration that empowers students to discover their unique strengths.

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AV Washington@AVWashingtonLab·1 Kas

I recently had the opportunity to speak at the @oaklandu Undergraduate Research Society, sharing insights and experiences with students and researchers. It was an honor to contribute to the discussions and engage with emerging scholars.

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AV Washington@AVWashingtonLab·7 Eki

Congratulations to Madison Luxmore and Prisha Mehta, undergraduate students at #AVWashingtonLab, for outstanding poster presentations at the Midwest Platelet Conference in KY! Always inspiring to see young researchers presenting complex concepts and engaging discussions.

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AV Washington@AVWashingtonLab·26 Eyl

Exciting News! Welcoming Dr. @SravyaNimmala to our lab! 🌟 A physician with hands-on clinical experience, she’s now pursuing a Ph.D. in medical research to address critical gaps in healthcare. Connect with her to discuss #Hematology #Research

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AV Washington@AVWashingtonLab·18 Eyl

An incredible milestone! Huge congratulations @SiobhanBranfie1 Ph.D. for completing her academic journey at @oaklandu Watching her pour her heart into this journey was inspiring. She’s lifted the laboratory to new heights. Hope to remain part of this incredible journey.

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AV Washington@AVWashingtonLab·28 Tem

Great summary of the signaling pathways involving regulation of #platelet ROS production and their role in platelet function and thrombosis.

JTH@JTHjournal

#Platelets are players #cardiovascular diseases such as atherosclerosis and venous #thrombosis. Reactive oxygen species (ROS) are generated within activated platelets. Read new review now! jthjournal.org/article/S1538-…

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AV Washington@AVWashingtonLab·26 Tem

Recently a colleague and I presented an action plan for inclusive teaching, marking the culmination of an incredibly valuable learning journey at @CETLatOU. Inclusive teaching is a commitment to ensuring that every student feels valued, respected & empowered to succeed.

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AV Washington@AVWashingtonLab·22 Tem

Our new publication @of_therapeutic TLT-1 plays a pivotal role by binding fibrinogen. Our assay identified 80 potent inhibitors to significantly reduce TLT-1 binding (80%) Promising avenue to combat thrombosis associated with cardiovascular disease. jpet.aspetjournals.org/content/early/…

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AV Washington@AVWashingtonLab·21 Tem

Implications of this study: platelets may prevent the exacerbation of ferroptosis-associated diseases dependent on CLEC-2; platelets bind different types of iron substances ➡️platelets may play a significant role in the regulation of pathophysiological iron homeostasis.

JTH@JTHjournal

Ferric chloride activates platelets through CLEC-2. Tsukiji et al find platelet CLEC-2 attenuates ferric chloride-induced endothelial ferroptosis. @clinlab_yama jthjournal.org/article/S1538-…

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AV Washington@AVWashingtonLab·20 Tem

Washington Lab spotlight: Yashieta immerses herself in the world of hematology, where she develops skills in cryosectioning, tissue analysis, and genotyping. Stay tuned as Yashieta continues to make strides in her research journey! 🧬💡 #Science #Research #Hematology #TLT1

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AV Washington@AVWashingtonLab·19 Tem

Inspiring career development discussion with young scientists of the Biomedical Research for University Students in Health Sciences Summer Research Prgm @michiganstateu!🌟It was energizing to engage with such articulate UG & veterinary students. They will do great things!

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AV Washington@AVWashingtonLab·18 Tem

Excited to announce our latest from #AVWashingtonLab a new protocol for murine whole blood aggregometry as an alternative to traditional light transmission aggregometry doi.org/10.1002/cpz1.1… @SiobhanBranfie1 @Curr_Protocols @WileyGlobal

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AV Washington@AVWashingtonLab·16 Tem

Actin filaments reside within human platelet microtubules ➡️ stress placed upon the microtubule network during motor-driven microtubule looping & sliding may facilitate the incorporation of actin into microtubules.

Mark Dodding@MarkDodding

Our latest paper on actin within platelet microtubules led by @ChisatoTsuji is now in print. nature.com/articles/s4146… Where else might those little turduckens 🦃🦆 be hiding? @BristolBiochem @UoBrisPPN

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AV Washington@AVWashingtonLab·15 Tem

New potential therapy for breast cancer involving #platelets from @BloodJournal. “Targeting this irregular multicellular interplay may represent a novel immunotherapeutic strategy for TNBC without the adverse effects of systemic IC inhibition”

Blood Journals Portfolio@BloodPortfolio

Procoagulant platelets use these IC molecules to misguide immune cell responses, thus promoting tumor progression. ow.ly/wWJo50SzPoX #plateletsandthrombopoiesis #immunobiologyandimmunotherapy

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AV Washington@AVWashingtonLab·11 Tem

BDUC (bleeding disorder of unknown cause ) patients show reduced platelet adhesion/ thrombus formation.➡️ To diagnose BDUC, platelet light transmission aggregometry should be performed as a minimum assessment. Platelet transfusions can be a potential treatment option.

JTH@JTHjournal

On #Cover #July New @isth SSC paper on bleeding disorders of unknown cause @MahaOthman8 @nikmutch @@Mtl_PlateletLab jthjournal.org/action/showPdf…

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ディスカバー

@oaklandu @SiobhanBranfie1 @CETLatOU @of_therapeutic @michiganstateu @Curr_Protocols @WileyGlobal @elonmusk