Kobe Lab

Check out our recent preprint on the structure of a non C-JID TNL resistosome from flax. We are very proud of the persistence of Natsumi who got this long running project over the line and a congratulations to all involved. Check it out... doi.org/10.64898/2026.…

If one TNL resistosome wasn't enough for you this weekend. Checkout another! Amazing work by all involved!

Structural basis of canonical TIR-NLR activation in plant innate immunity biorxiv.org/content/10.648… #biorxiv_plants

We wrote a focussed review on recent structural advancements in NLRs. It was a lot to cover we tried our best. We hope its enjoyable to experts in the field and useful to newcomers. Check it out: doi.org/10.1111/tpj.70…

Little one’s first interstate conference done #ASBMB2025 Thank you to @ITSASBMB and local organisers @buffalo_berger @Kobe_Lab_ @ UQ for the support! Great conference great to be back!

I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5) doi.org/10.1101/2025.0…

ASBMB2025!

Excited to see our Arabidopsis TIRome paper published in PNAS. Have a read here doi.org/10.1073/pnas.2…. We hope this is the start of tuning TIR domains 😎

Excited to be at #2025ISMPMI come see me at p16 Tuesday to hear more about TIR domains and an effector that inhibits flax TNLs

Great job at 3MT!!

Plant TIR domains are the coolest TIR domains! Privileged to be a part of this work, that is up on bioRxiv. biorxiv.org/content/10.110… @Kobe_Lab_

Excited to share our work in @PNASNews . We report the cryoEM structures of both TRIF and TRAM uncovering the molecular basis of TRIF-mediated TLR3 and TLR4 signalling pathways. pnas.org/doi/10.1073/pn…

It has been a roller coaster year for me after experiencing extreme happiness and loss. Today I’m starting as a new PI @ANUChemistry. Very grateful to all my extended academic family @BiologyANU and all past and current mentors. Looking forward to forge new networks and collabs!

This week we had the pleasure of hosting cryo-EM guru @OliBClarke who gave the @UQ_News cryo-EM community a fantastic cryo-EM data-processing workshop. Thank you Oli for sharing your tricks with us, @FarrahBlades for wrangling the Bunya supercomputer, and all who attended! 🔬

Had a blast the last couple of days learning how to use our brand new Oryx8 crystallisation robot from @DougInstruments! First robot for the lab and first Oryx8 in Australia! 💎 #gulbaliinstitute #charlessturtresearch

2024 @UQ_SCMB Structural Biology division retreat. Another fantastic three days of science, sun and fun!

And so it ends … 3 days of fantastic science and beautiful Freo weather #crystal35 #scanz. Thanks to everyone who joined us from Japan, Korea, India, South Africa, Singapore, UK and USA. And of course our amazing Australian and New Zealand structural science community!

All the rising stars of Crystal35 conference @Crystal_SCANZ 🎉💎🥳👏👍🥂 Congrats everyone

Exciting session at Crystal35 conference @Crystal_SCANZ with the “rising star awards” starting with @bj_charles @MonashBDI 🎉 congrats

Congratulations to @JackKClegg for the 2024 SCANZ Mathieson Medal! @RACInational @UQ_SCMB 🥳