Dalton (Analyze & Optimize)

It's sad that most people live their entire lives in a perpetual state of lowered consciousness, they don't even realize that they aren't who they think they are. ➥ Brain fog / neuroinflammation ➥ Poor mitochondrial function ➥ Low dopamine ➥ Hormones out of whack All of this completely distorts your reality, causing you to be more self conscious, dull, tired, fearful, etc. Less creative, expressive, loving. Only by correcting your health can you discover your true self once again. You can cut through all of that. We can help get you there. Reach out if you need help. Your life depends on it. start.prism.miami/scheduling

@celestial_chic amazing!!

@Outdoctrination When my then 4 yr old started taking vitamins like the one you showed below he began speaking.

Autism is a mitochondrial disorder - and restoring their function can improve it, demonstrated beautifully in a recent trial. (🧵1/8)

@SUN_MOON_NATURE hear this all the time

@Outdoctrination Wow. It's true. I started eating fresh pineapple every morning for breakfast for the past 3 weeks and I had floaters in both eyes. They are now gone! Try it. It's also a delicious start to the day.

Eye floaters eliminated with fruit enzymes. This study used: ⬩190 mg bromelain ⬩95 mg papain ⬩95 mg ficin Literally dissolves the floaters away within months. ⬩92% of people felt “bright” ⬩90% felt better or much better ⬩92% were satisfied after supplementing. ◇ Pineapple ◇ Papaya ◇ Fig are some foods with these enzymes, which tear apart the collagenous eye proteins.

@lilithsappetite @BlackOrpheusAmi this one pmc.ncbi.nlm.nih.gov/articles/PMC96…

@BlackOrpheusAmi @Outdoctrination It’s 2026 and you need a big pharma ghost written pseudo scientific source as proof first?

@Stan2415loveu yes, check out the quoted thread

@Outdoctrination Anything else improve

Niacinamide (vitamin B3) is a powerful anti-fungal, even against Candida. ➱ Coated tongue ➱ Digestive issues ➱ Fatigue ➱ Insatiable sugar cravings ➱ Excess estrogen ➱ Skin issues are some signs of fungal / Candida overgrowth. 500 mg 1-3X daily is a good place to start.

@balanced_alex yes haha very cute but seriously a lot of people actually do struggle a lot with it it's not always this quirky meme personality trait that the internet makes it out to be

@Outdoctrination I'm sorry, I'm going to keep this one.

@USAFAN311472 i havent seen them compared h2h, but they do the same mechanistically. NAC has more study behind it

@Outdoctrination Why NAC over liposomal glutathione? Taking for immune support. Is either ok?

NAC is able to increase testosterone and semen volume / quality, shown in a number of clinical trials. (🧵1/7)

@ManTicktoc41268 it does tho aop-health.com/global_en/pres…

@Outdoctrination No, it doesn't.

Coenzyme Q10 cuts death risk from sepsis in half in trial. Globally, sepsis kills about 20% of people every year - it's when bacteria enter the bloodstream. Something as simple and cheap as CoQ10, 100 mg orally twice daily, here was shown to reduce death risk: ➠ Control: 65% ➠ CoQ10: 20% CoQ10 is a critical player in the mitochondrial electron transport chain, which typically fails during sepsis. Also reduced TNFα - a key mediator of the septic response.

@aricarbins also true

@Outdoctrination "Evidence suggests that higher levels of cholesterol, specifically high-density lipoprotein cholesterol (HDL-C), can be protective against sepsis, while low cholesterol levels are associated with a higher risk of mortality."

@Jacob76957217 you're welcome!

@Outdoctrination Golden post🙌.Thank you

The ultimate supplement to boost your metabolism: THYROID HORMONE - A complete guide 1. Symptoms you may be hypothyroid Just to name a few: • ALWAYS being tired • Feeling COLD, especially at the extremities • Slow / lethargic speech • Stubborn weight gain • Poor mood • Puffy features: cheeks, love handles, general water retention • Gynecomastia (man boobs) • Muscular weakness • Dry skin and hair • Anxiety • Hair loss • Always being sick Digestion is particularly responsive to thyroid hormone. • Constipation or diarrhea • Nausea • Bacterial overgrowth • Reflux are all common in hypothyroidism. Thyroid hormone is: ⬨ Key for gut regeneration, healing ⬨ Pro-motility ⬨ Vital for producing digestive enzymes ⬨ Required for producing stomach acid ⬨ Critical for gut immunity, gut barrier 2. Why labs are often misleading TSH is the primary (and often only) metric a doctor will test for hypothyroidism. A lower TSH should be indicative of higher thyroid hormone secretion, but it doesn't tell the full story. For starters, TSH can be lowered by: • Infection • Trauma • Cortisol • Adrenaline • Caffeine • Fever So a low TSH alone cannot rule out hypothyroidism. The standard TSH reference range is also WAY too lenient (up to 5). TSH >2 has been associated with: • Heart disease • High cortisol Thyroid hormones: • T4 (inactive) • T3 (active, pro-metabolic) • Reverse T3 (anti-metabolic) can also be measured in the blood, but this doesn't tell the full story either. These hormones must be transported through the blood, enter their target cells, and attach to the specific proteins in the cells that facilitate their actions. Not as simple as thyroid in blood = thyroid activity. Values of the “free” T3 and T4 can be misleading as well. Thyroid hormones do not need to be "free" to exert their effects on various tissues, contrary the current medical dogma. I still think testing can often be helpful, but you can certainly be hypothyroid while your labs look good on paper. 3. Diagnostics An underarm temperature measured first thing in the morning, leaving the thermometer under the arm for 10 minutes to equilibrate, should start be >97.8°F. Lower temperatures are highly indicative of hypothyroidism. This was the gold standard thyroid test (along with aforementioned symptoms) that was successfully used to treat thousands of hypothyroid people before blood tests. You can have “ideal” thyroid lab values yet be at the temperature of a hibernating bear. A healthy resting pulse averaged 85 beats per minute, though Dr. Ward Dean has suggested between 65-75 is a good range. If you eat carbs can and feel more tired and have lower temperature and pulse rate, this indicates a reliance on the stress hormones and a lack of thyroid function. The response of the Achilles tendon when tapped was another assessment tool. In a well-functioning thyroid, the foot would swing back energetically due to quick muscle relaxation. but a slow, controlled return motion indicated potentially sluggish energy status, often a sign of hypothyroidism. High cholesterol is another sign of hypothyroidism, while thyroid supplementation normalizes it. 4. NOT supplementing thyroid is unnatural Consuming thyroid gland is as natural and "ancestral" as it gets. Paleo researchers have stated that we probably consumed lots of thyroid gland throughout human history: "the shift from scavenging towards hunting... would have increased thyroid gland consumption by hominins and thereby exogenous thyroid exposure." "these Homo forebears started consuming small animals, such as amphibians, birds, and reptiles. This prey was consumed whole, and the animals’ thyroid glands thus provided a significant amount of thyroid hormone to their hominid predators." "Nevertheless, tissues and organs (including thyroid glands) are commonly consumed by the primary hunters" In fact, thyroid gland used to be in common foods like ground beef up until the mid 80s. It is only recently when we stopped eating the whole animal, including the thyroid gland! 5. Using natural desiccated thyroid (NDT) Desiccated thyroid comes from the thyroid glands of pigs or cows, and is the traditional way of supplanting thyroid hormones. A grain (60 mg) is the unit of measurement for supplementation, containing ~40 mcg T4 + ~10 mcg T3. A starting dose of a half grain is reasonable, and should be continued for 2-4 weeks before adjusting. The hormones take around this long to stabilize. As you use NDT, you should consistently track: 1. Morning temperature 2. Symptoms Once you get to >97.8°F and symptoms resolve, the correct dose has been found. The brand matters a lot. Many products seem to be unreliable, or outright useless. That’s definitely been my experience. I’ve tried numerous products over the last few years. I'll link below the thyroid product I have been using recently for myself and with clients. I would take it with food to slow the absorption, or even split into multiple doses with meals. I prefer at dinner. While some may require full replacement (4 to 5 grains), others find relief with as little as 15 mg (quarter grain). Broda Barnes observed that his patients often required about two grains of thyroid to alleviate hypothyroid symptoms, occasionally needing more. If you experience • Too fast of a heart rate • Palpitations, • Anxiety, • Overheating • Fatigue • Shaky feelings then you might have taken too much thyroid. The amount taken should be reduced or discontinued entirely. Effects of over stimulation should resolve in a few hours. This type of response can also indicate low cholesterol or an issue with liver function, two systems that the thyroid depends on to do its good. You may also need more nutrients, as the increased metabolic rate demands more resources. Eat your liver, egg yolks, and oysters. Many people who should be candidates for supplementation find that thyroid does nothing for them, no matter how much they take. In my experience, this always seems to be tied to an issue with the gut. I would try to address this first. Or, you just may not need it at all. You may need to address other factors. Of course, supplementing thyroid is not the ONLY way to improve thyroid function, but it seems like an appropriate strategy when other factors have been addressed.

@AKA_Sadrien i dont think its MOA is dependent on SIRT1, plus there are some human studies showing benefit

@Outdoctrination Isn't this resveratrol 2? Another hormetic SIRT1 derived respiratory toxin that will only work in rats because human sirtuin / PGC-1a interactions are different and the doses used non-viable in humans in the first place?

Urolithin A extends lifespan by ~14-19% in study. Urolithin A is a bacterial metabolite of certain polyphenols found in pomegranate and strawberries. Roughly 30 mg human equivalent in animals was shown to increase: ◇ Max lifespan by ~14% ◇ Median lifespan at 80th %ile mortality by ~19% Urolithin A promotes the process of mitophagy - which clears old / damaged mitochondria and thus improves whole body metabolic health.

And you can actually get this exact measurement done at home using MITOME. It's just a cheek swab that pinpoints mitochondrial components' functioning. mito.me/?via=dalton

The main high level findings of the autistic brain are: 1. Alterations in the size of key brain regions 2. Abnormalities in the connectivity between different brain nodes Both of these are tightly connected to energy production and thus mitochondrial function. When mitochondria aren't working properly: ➮ Reactive oxygen species production and thus neuroinflammation increases ➮ Neurotransmitter synthesis and regulation is thrown off ➮ Ion gradients are not maintained properly ➮ Neuron structure is not properly maintained The brain does not work without energy production working properly, and this is a huge part of the autism puzzle.