Reiter Lab

Please read and critique our new paper on the genetic determinants of human kidney function @NatureGenet: rdcu.be/dTwye We combined GWAS with CNN and CRISPRi to go from loci to target genes. This roadmap may be useful to others uncovering genes underlying human traits.

Thrilled to share our new study in collaboration with @TerenceRyan_PhD. We find that intramuscular adipose tissue (IMAT) directly impairs limb muscle function in PAD/CLTI and that preventing IMAT formation improves functional outcomes in experimental PAD. tinyurl.com/3efwaerh

Check out this article in @ScienceMagazine featuring our Vilcek Prizewinners: Karolin Luger, @TakashiAkeraLab, @AashishManglik, and @BernaSozen_ !👏 These immigrant scientists are shaping the future of medicine, from uncovering the hidden mechanisms of our cells to advancing treatments for disease. 🔬✨ Read more about their discoveries: vilcek.co/3OxUKFG

Polycystic kidney disease is the most common monogenic cause of kidney failure and affects over 10 million individuals. We've known most PKD is caused by mutations in PKD1 for over 30 years. But how PKD1 prevents disease has remained mysterious, limiting effective therapy.

Janelia is hiring Group Leaders! Work alongside superstars like Luke Lavis, @JiefuBiol, @mengwang939, @JLS_Lab, @ERSchreiter. If you have ideas that are perhaps too ambitious or crazy for a traditional academic setting, that is exactly who they are looking for. Tool-builders at all career stages with original, transformative ideas for experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, and methods that don’t yet exist: Apply by Feb. 3, 2026: janelia.org/groupleader

Excited to have my first senior author publication out in the world! An awesome collab between myself in the @ReiterLab and the Berbari lab at IU. We found primary cilia are necessary for postnatal pituitary development. 1/n. sciencedirect.com/science/articl…

Save the date! PKDCON returns in 2026. Join us June 12–13 in the Chicago metro area, either in person or virtually. We can’t wait to see you there!

Check out the latest work from our lab, done in collaboration with @FriedmanJed . Work was led by @sarah_jane210. @OuhscN

Alex Yashchecko, the first Ph.D. Student in lab, is defending his thesis today!

In their Cell Science at a Glance article, Dagmar Wachten & Søren Tvorup Christensen @t_soren explore the primary cilium as a master regulator of cellular communication that integrates diverse signalling pathways in development & homeostasis. #JCSciliaSI journals.biologists.com/jcs/article/13…

Good morning, Bay! I’m up early to head out to University of Florida @uflorida and Daniel Kopinke ⁦@KopinkeLab⁩. I hope to see you at the Dept of Pharmacology seminar Wednesday!

I am excited to share our preprint of CiliaTrack, a novel machine learning approach to PCD diagnosis. Proud of Nicolas Hadas, a talented PhD candidate in my lab, for developing the code and his amazing work on this project. biorxiv.org/content/10.110…

Check out our latest manuscript where we generate a cross model single cell and spatial atlas of mouse PKD! A cross model spatial and single-cell atlas reveals the conserved involvement of osteopontin in polycystic kidney disease | bioRxiv biorxiv.org/content/10.110…

More than 12 million people globally are impacted by ADPKD, and it still lacks disease-modifying therapies. Renasant Bio is on a mission to advance next-generation treatments for ADPKD through the development of small molecule correctors and potentiators. renasantbio.com/news-071025

Thank you to all PKD community members who have advocated over the years, and all who are standing up for the PKD community during this important time. Together, we can #EndPKD. Want to add your voice? Join our Advocacy Champions Network: bit.ly/4l4nl0S

Whitehead Institute Founding Member Rudolf Jaenisch has received the 2025 Ogawa-Yamanaka Stem Cell Prize, which recognizes his seminal role in establishing and advancing the field of induced pluripotent stem cells (iPSCs). wi.mit.edu/news/rudolf-ja… @GladstoneInst

Excited to share our new paper! mtDNA mutations contribute to mitochondrial disease and aging only if they rise in abundance. We show that deleterious mutations reach high abundance by hitchhiking on genomes that have a replicative advantage rdcu.be/eugVO

#Postdoc opportunity at Columbia U. in New York! We are interested in candidates from biochemistry backgr. & excited about fractionation, purification and reconstitution to study autonomous clocks in the cell cycle, in colab. w/ @Aydinlab at NYU! hhmi.wd1.myworkdayjobs.com/External/job/C…

Not only does UCSF's NIH-funded research advance health care and improve patients' lives, it has an estimated $18.7B ripple effect on the economy. The result is more innovative startups, more jobs, and stronger companies that hire workers nationwide. tiny.ucsf.edu/SavingLivesWit…

📢 𝗦𝗔𝗩𝗘 𝗧𝗛𝗘 𝗗𝗔𝗧𝗘! Join us Sept 4, 9 am EST for the Space on Polycystic Kidney Disease in recognition of #WorldPKDday 🗣️ Experts: @PKDCharity @fouadchebib @CaplanMic62185 Hosts: @myadla @Dilushiwijay @dra_miliflores ⏰ Set your reminder: x.com/i/spaces/1ldxl… #PKD #endPKD #ADPKD #ARPKD

My birthday is a joyful milestone. Seeing our work published is a proud achievement. Having both happen on the same day — truly unforgettable! Thank you @NatureMedicine🥳 Excited to share our new study: The proteogenomic landscape of the human kidney and implications for cardio-kidney-metabolic health by Daigoro Hirohama et al."nature.com/articles/s4159…