Leslie Sombers

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Leslie Sombers

Leslie Sombers

@SombersLab

Prof of Pharmacodynamics at U. Developing independent thinkers, building electrochem tools for monitoring molecules in the brain, and discovering new things

Gainesville, FL 参加日 Mart 2019
176 フォロー中681 フォロワー
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Leslie Sombers
Leslie Sombers@SombersLab·
#crushingit in Gainesville!!! The UF lab is renovated and ready, students have safely made the trip, and @JovicaTodorov1 's enkephalin paper is featured as a cover for Analytical Chemistry! Artwork credit goes to our own @OneMetricDylan .
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Leslie Sombers
Leslie Sombers@SombersLab·
@nanopharmNC Same. You’re not alone. I haven’t spoken to either parent because my mother supports my father in his abuse and I’m a sinner for not ‘honoring my father’.
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Leslie Sombers
Leslie Sombers@SombersLab·
Gracey McNair representing the NC contingent of the lab at the NCSU Chem undergraduate research poster sesh. Inspiring young minds !! 💪👍 Go Gracie!!
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Leslie Sombers
Leslie Sombers@SombersLab·
@RossLabUC I usually just don’t attend if it’s after 3:30. I simply can’t make it
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Dr. Ashley Ross
Dr. Ashley Ross@RossLabUC·
Can we stop scheduling events/seminars/etc constantly after 4 pm. It is hard for people with kids. I understand occasionally having these things but it feels like every other university-related event is held in the late afternoon and as a momma of 3, my priorities are different.
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Leslie Sombers
Leslie Sombers@SombersLab·
When using electrochemical detection strategies in live tissue, we are always worried about selectivity. Here, dioxythiophene monomers were mixed with Nafion and used to create a membrane with nanostructured pores of increasing size.
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Leslie Sombers
Leslie Sombers@SombersLab·
The modified electrodes exhibited enhanced selectivity for smaller peptide species over larger peptides in a manner consistent with the size of the dioxythiophene monomer incorporated into the polymeric film, allowing for tunability in terms of size-based selective detection.
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Leslie Sombers
Leslie Sombers@SombersLab·
The modified electrodes were characterized in the voltammetric detection of dopamine and a series of tyrosine containing neuropeptides of increasing size: met-enkephalin (M-ENK), oxytocin (OXY), neurotensin (NT), and neuropeptide Y (NPY).
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Leslie Sombers がリツイート
Matthew Dominick
Matthew Dominick@dominickmatthew·
Timelapse flying by Hurricane Milton about 2 hours ago. 1/6400 sec exposure, 14mm, ISO 500, 0.5 sec interval, 30fps
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Leslie Sombers
Leslie Sombers@SombersLab·
This week was national postdoc appreciation week and we want to give a shoutout to our awesome postdoc, @JovicaTodorov1! Jovica studied voltammetry as a grad student at NCSU, and as a postdoc at UF he is learning electrochemical impedance spectroscopy 💪 #somuchpotential
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Leslie Sombers
Leslie Sombers@SombersLab·
UF academic year kickoff - here's to new beginnings! Wish @JennaBerger4 was here too! 🧡
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Leslie Sombers
Leslie Sombers@SombersLab·
THIS! This is the Sombers Lab!! These are the amazing people who have done the work since we began at NCSU in 2008, through the present at UF. Training these researchers is my most significant contribution to science and I am so proud. Go Team!!!
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Leslie Sombers
Leslie Sombers@SombersLab·
#crushingit in Gainesville!!! The UF lab is renovated and ready, students have safely made the trip, and @JovicaTodorov1 's enkephalin paper is featured as a cover for Analytical Chemistry! Artwork credit goes to our own @OneMetricDylan .
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Leslie Sombers
Leslie Sombers@SombersLab·
A factory is used to represent synthesis of custom peptides cleaved from pro-enkephalin. The illustration shows a team of scientists seeking to understand detection of these peptides using electroanalytical signatures dictated by chemical structure.
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Leslie Sombers
Leslie Sombers@SombersLab·
Overall, this study demonstrates how fast-scan cyclic voltammetry can be utilized to discriminate between peptides with small differences in the chemical structure, thus establishing a framework for reliable quantification of small peptides in a complex signal, broadly speaking.
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