David Lederer

A2:This helped me 1. List each activity you engage in at work 2. Add 3 checkboxes to each row: Am I good at it? Does it make me happy? Is it only boosting my ego? (yeah, brutal) 3. Cross off the ego boosters 4. Find a job that you are good at and makes you happy #ATSchat

@jskim8223 @IPFdoc @ActionPFcharity @EU_IPFF @CARE_PF Yes! if you hear crackles, please strongly consider ILD on the differential diagnosis Also if you suspect ILD, get a high res CT (it rhymes)

@IPFdoc @ActionPFcharity @EU_IPFF @CARE_PF @davidlederer would teach us if you hear crackles, please strongly consider ILD on the differential diagnosis

#MedTwitter Giving lecture 2 PrimaryCar tomoz about #ILD Key messages will b: 1: There is more of it than u think 2: Early diagnosis protects lung function 3: Identify & mitigate risk factors 4: Recognise & manage co-morbidities Anything else? @ActionPFcharity @EU_IPFF @CARE_PF

@GlassbeMK Not convinced that it is definitive proof that GERD causes IPF. It is evidence for a causal effect. So is WRAP-IPF.

Who’s convinced?

@LungDrE @IPFdoc @gburgeILDNN @drcjar This odds ratio came from a mendelian randomization study, meaning that the instrument was genetic variants associated with GERD. I find it impressive that GERD genetic variants were associated with IPF risk. This is evidence of a causal effect.

So there we have it: GORD (GERD) causes IPF but IPF does not cause GORD! #WatchThisSpace 👏@drcjar The causal relationship between gastro-esophageal reflux disease and idiopathic pulmonary fibrosis: A bidirectional two-sample Mendelian randomization study medrxiv.org/content/10.110…

Thanks all. Happy to chat 1:1 with anyone about careers #ATSchat

In the end it comes down to what we have all mentioned. This is a start. Reach out to any of us or all of us and lets chat more. #ATSEARLYCAREER #ATSChat

@lungDrE I agree, Eric. Pretty amazing to see what can happen when you fully fund a development program run by a fantastic team #ATSchat

A4: In academic research, the focus is on knowledge generation. In industry, the focus is (generally) drug development. This means attention to strategy and risks, which are not really considered in academia. This was totally new for me! #ATSchat

@lungDrE #ATSchat I am having the same thought @lungDrE

@Moder8or1 #ATSchat. it's true. you can learn clinical research on the job!

@davidlederer I like - and am somewhat surprised by - the fact that clinical research background is a plus, whereas interpersonal skills, emotional intelligence, and clinical knowledge & experience are closer to "must-have". #ATSchat

A3: Important qualities: interpersonal skills, emotional intelligence, clinical knowledge, clinical experience. Clinical research background a plus #ATSchat

A2: Talk to LOTS of people both in and outside of industry. 280 characters is not enough (DM me, seriously). #ATSchat

A1: clinical development, medical affairs, pre-clinical scientist, translational scientist, biostatistics, regulatory affairs, pharmacoepidemiology, pharmacovigilance, and more… #ATSchat

hey everyone! excited to be here #ATSchat

@docgrose I will listen to your lecture

@docgrose rebrand it

Looking forward to this #ATSchat about careers in industry tomorrow at 8pm ET @atsearlycareer @atscommunity

Folks — This will be the account for my official duties as President. At 12:01 PM on January 20th, it will become @POTUS. Until then, I'll be using @JoeBiden. And while you're here, follow @FLOTUSBiden @SenKamalaHarris @SecondGentleman and @Transition46.

@docgrose I had the same reaction