SPRK

2.4K posts

SPRK

SPRK

@poolflips

参加日 Haziran 2022
275 フォロー中193 フォロワー
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BioBoyScout
BioBoyScout@BioBoyScout·
BIIB080 floods the cortex but barely reaches the hippocampus. $ARWR ARO-MAPT goes subcutaneous through the transferrin receptor and hits the deep brain uniformly. Same target. Better real estate. New paper on the 2H2026 readout setup, now on Substack: bioboyscout.substack.com/p/aro-mapt-the…
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SPRK
SPRK@poolflips·
@Jabs_13 He actually had some great opportunities to make plays. But he has developed tunnel vision for flopping and injuring ppl
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Jack Jablonski
Jack Jablonski@Jabs_13·
I’d like to the NHL Player Safety for not suspending Jamie Benn. There was a lot of attention on Benn in this series for his cheap plays, but man what a horrendous series for the #TexasHockey cap’n. 6 Games: 0 goals 0 assists 0 points -7 #mnwild
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BioBoyScout
BioBoyScout@BioBoyScout·
$ARWR trades at over $10B today. If ARO-MAPT's Phase 1 reads positive in 2H 2026, the math says it's worth $55-$90B to a strategic acquirer. Not a guess. Four independent methodologies. Same range. Full paper: drive.google.com/file/d/1D5eD6Y…
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Sam Richards
Sam Richards@MinneapoliSam·
Minnesota wins again. Quality of life and affordability metrics top the chart-- all nine measured beat the national average.
Sam Richards tweet media
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mr_eggs 🇵🇸
mr_eggs 🇵🇸@scrumble_eggs·
I’ve pooped in toilets you wouldn’t even piss in.
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Team USA
Team USA@TeamUSA·
Fifty states. One podium. 🇺🇸 Team USA’s medal haul spans the map. #WinterOlympics
Team USA tweet mediaTeam USA tweet media
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Clemente
Clemente@Chilearmy123·
Interstellar but Cooper's son is the worst trader of all time
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Wild trading
Wild trading@YYDSxjm·
$IOVA has 4 big near-term catalysts that could ignite serious upside: Tandem Meetings 2026 Real-World Data Drop New real-world evidence on Amtagvi in advanced melanoma (building on strong ~49% ORR commercial data). Q4 2025 Earnings + 2026 Guidance Expected Feb 26, 2026. With 2025 revenue guidance reaffirmed at $250-300M and >1,000 patients treated, look for accelerating sales, margin gains from in-house manufacturing, and potentially upbeat 2026 outlook to spark a rally. Endometrial Cancer Results (IOV-END-201) Initial data from Phase 2 in advanced endometrial cancer (post-PD-1) on track for early 2026. Huge unmet need—no approved options here—positive readout could unlock a new major indication and expand the platform massively. IOV-4001 (PD-1 Knockout TIL) Results Clinical results in previously treated advanced melanoma expected Q1 2026. This next-gen engineered TIL could show boosted efficacy over standard—
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zohm
zohm@zohmbastic·
$IOVA interesting March 3.5c flow today
zohm tweet media
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Jason Bassler
Jason Bassler@JasonBassler1·
Two cults. One mantra. Zero critical thinking.
Jason Bassler tweet media
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BioBoyScout
BioBoyScout@BioBoyScout·
1/3 $ARWR just priced financing at an institutional premium, not a fire sale. Zero-interest convertible notes at a meaningful premium plus a modest equity raise locks in years of runway. That structure matters.
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