Corry Lab

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Corry Lab

Corry Lab

@CorryLab

Computational protein research group of Prof Ben Corry @ourANU @ANU_RSB_BSB ~Tweets by group members

Canberra 가입일 Ocak 2022
279 팔로잉691 팔로워
Corry Lab
Corry Lab@CorryLab·
How does your immune system tell pathogenic RNA from your own, even though they’re made of the same stuff? Our latest paper with @GantierLab shows some self RNA act as an off switch preventing autoimmunity in the absence of pathogens. 🧬🔬⭐ nature.com/articles/s4159…
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Corry Lab
Corry Lab@CorryLab·
Beginning 2026 with a flipping good paper🚀OSCA/TMEM63 proteins do double duty: they’re ion channels andmechanically activated lipid scramblases helping reshape membranes and survive mechanical stress. 👏@yiechanglin @Charles_D_Cox doi.org/10.1038/s41467…
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Corry Lab
Corry Lab@CorryLab·
2 yrs ago @yiechanglin sent me this of lipid scrambling by OSCA1.2. Now we show it’s common to WT OSCA/TMEM63 proteins, mechanically activated, cholesterol dependent, and protects cells from damaging forces. Awesome collab with @Charles_D_Cox &Zhang lab. tiny.cc/tmem63
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Corry Lab
Corry Lab@CorryLab·
🌟We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids🌟 Join us at @ourANU with amazing collaborators and great working conditions! Apply: tiny.cc/corry. Us: karri.anu.edu.au
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Corry Lab
Corry Lab@CorryLab·
We show where chloroquine and peptides bind and help explain the polyspecific transport mechanism. (2/2)
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Corry Lab
Corry Lab@CorryLab·
Excited to share @john_d_tanner's new work in Nat Coms! We demonstrate how PfCRT, a polyspecific peptide transporter, turns into a drug transporter for antimalarials like chloroquine and why this causes a fitness cost for the malaria parasite (1/2) tiny.cc/PfCRT
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Corry Lab
Corry Lab@CorryLab·
Also bittersweet to announce the final work of @whoiselainetao in our lab, using AF2 to study conformational transitions in 32 voltage-gated channel superfamily members 🤩 we're so excited to watch you Nav-igate the next steps of your career, Dr. Tao 🎩 tiny.cc/VSD-AF2
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Corry Lab
Corry Lab@CorryLab·
Bittersweet to announce YC's final work in our lab. We are so proud of everything she's accomplished (incl. this beautiful study showing how the TAM complex facilitates lipid flow between the bacterial inner & outer membranes). We can't wait to see what you do next, Dr. Lin 🤩
YC Lin 🧪👩🏻‍💻@yiechanglin

1/ In my final project as part of the @CorryLab, we show the bacterial TAM complex facilitates the spontaneous flow of phospholipids from the IM to the OM in MD simulations.. biorxiv.org/content/10.110…

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Corry Lab
Corry Lab@CorryLab·
Thrilled to share our latest preprint from @yiechanglin & @ciara__wallis showing AF2-Multimer and AF3 can quickly & accurately predict the oligomeric states & structures of proteins (& maybe can identify multiple biologically relevant oligomeric states 👀) tiny.cc/oligomers
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Corry Lab
Corry Lab@CorryLab·
Proud of our latest work w/ the Zhang lab showing from structure & simulation how XPR1, the only known human Pi exporter, is regulated by InsP8 & KIDINS220 + Pi selection/permeation by a channel-like knock-kiss-kick mechanism 💻 @ciara__wallis @Riottowow tiny.cc/xpr1
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Corry Lab
Corry Lab@CorryLab·
Excited to start the year with this lovely paper with @whoiselainetao showing that drugs that inhibit sodium channels bind in a range of sites within the pore cavity rather having a single distinct pose. @JGenPhysiol @scienceANU @NCInews
Journal of General Physiology@JGenPhysiol

Tao and Corry @CorryLab @ANU_RSB_BSB investigate the binding of sodium channel inhibitors to the Naᵥ1.5 pore using simulations, revealing promiscuous, polyspecific binding at the fenestrations and central cavity. hubs.la/Q031spy70

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Corry Lab 리트윗함
Angelika Lampert
Angelika Lampert@LampertLabRWTH·
Nav computer modelling as tool to understand fast inactivation: join us for the next worldwide sodium channel seminar given by Ben Corry on December 17th. More info on sodiumchannelseminars.org. Mark your calendar and join the discussions!
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Corry Lab 리트윗함
Charles Cox
Charles Cox@Charles_D_Cox·
Celebrating a birthday and good news from grants @Dr_Albarose congrats to the @CorryLab on their @arc_gov_au Discovery Project :) the rest is 🤫
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Corry Lab
Corry Lab@CorryLab·
@ARC_Tracker I have noticed that our college internal EOI submission deadline is before the likely announcement of the DP25 outcomes... Are we meant to assume our current application will be rejected🤔😆
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탐색

@GantierLab @yiechanglin @Charles_D_Cox @whoiselainetao @ourANU @john_d_tanner @ciara__wallis @scienceANU