Dan Browne

@strnr At first I thought this was the other CLEAN (github.com/tttianhao/CLEAN). Namespace collision!

Targeted decontamination of sequencing data with CLEAN biorxiv.org/content/10.110… 🧬🖥️🧪 Nextflow: github.com/rki-mf1/clean

NEWS: We’ve announced LanzaX, a dedicated business unit for our synthetic biology platform, which we intend to spin out as a joint venture with Tharsis Capital in the coming months. Learn more: ir.lanzatech.com/static-files/0…

X-Mapper: fast and accurate sequence alignment via gapped x-mers genomebiology.biomedcentral.com/articles/10.11…

Every synthetic biologist, every biochemist, when they dream, will sometimes hear a voice calling A whisper on the wind, as impossible as infinity, as sweet as the ambrosia of the very Gods "Engineer RuBisCo" And this paper takes us one step closer nature.com/articles/s4158…

Talk of the town: @RocheSequencing SBX sequencer web.cvent.com/event/e7756666…

Memory makes computation universal, remember? thinks.lol/2025/01/what-c…

What is needed to accelerate enzyme engineering using machine learning? #Data We develop a ML-guided platform that integrates DNA assembly, gene expression, and functional assays. ML models predict improved variants. @akarimlab @NUSynBio @NatureComms nature.com/articles/s4146…

Do you make core genome alignments for phylogenomics? @monaltaouk and I explored how including sites with some missing data (a soft core) can improve analysis, especially for large datasets. microbiologyresearch.org/content/journa… (1/4)

ntSynt-viz: Visualizing synteny patterns across multiple genomes biorxiv.org/content/10.110…

Recent advances in recombinant production of soluble proteins in E. coli …robialcellfactories.biomedcentral.com/articles/10.11…

In creating a new C industry, we run w those that lean into & understand the need for change & get past C abatement as a singular solution vs one that creates jobs/value/opportunity. Incumbents never redefine the future. We run w like minded. Others will follow when we are done.

🌲 New tutorial on sandbox.bio: Learn to build phylogenetic trees from closely related genomes using ska2. sandbox.bio/tutorials/ska2…

Our review on pangenome graphs for biodiversity is out nature.com/articles/s4158… congratulations @secomandisimona @erichjarvis et al. It's a happy and sad day as one of the authors is no longer with us. We will miss you dearly

Scientific drawing is an important skill that used to be an integral part of a scientists training 📝 I use vectors for my drawings- here are 5 reasons why they are awesome (1/6 🧵)

From ⁦@Quantum_Si⁩ Detecting Amino Acid Variants Using Next-Generation Protein Sequencing (NGPS) | bioRxiv biorxiv.org/content/10.110…

$LNZA: Update on LanzaTech’s project with @ntpclimited (India's largest power generation company) for the first 4G ethanol plant highlighted in local news outlet. This plant will convert 100% carbon dioxide and green hydrogen into essential fuels, chemicals, and raw materials. business-standard.com/amp/content/pr…

Super cool! DNA is a great medium for ultra long-term, low-cost data storage. Love this application of synthetic biology

An aerogel made from gelatin and DNA surpasses 100% solar reflectance, yielding exceptional radiative cooling, a Science study reported last year. The novel approach paves the way for high-performance next-generation radiative cooling materials. scim.ag/7zw

@rrwick Man, I just finished building an automated pipeline with Trycycler to assemble bacterial genomes from HiFi reads (works great BTW). Very happy to see Autocycler though, can't wait to give it a try!

Autocycler is still new and evolving. I'll continue to improve it based on your feedback. A big thank you to the alpha testers who gave me feedback before this release! Give it a try and share your thoughts. (5/5)

New year, new assemblies! I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes! It's the successor to Trycycler, designed to be faster and less reliant on user intervention. Check it out: github.com/rrwick/Autocyc… (1/5)