
Daichi Inoue Lab (Japanese)
215 posts

Daichi Inoue Lab (Japanese)
@DaichiInoue_Lab
大阪大学医学系研究科がん病理学教室。生命機能研究科兼任。がん、白血病、造血幹細胞、発生を🧬RNA/代謝/クロマチン/ニッチ/細胞死など多様な視点から研究しています。 https://t.co/jpVu9XUnen 英語アカは@DaichiInoue5






Excited to share our latest work in @BloodPortfolio "Plenary Paper"! We present a comprehensive molecular and functional map of NUTM1-rearranged (NUTM1-r) leukemia. Why does this subtype show such favorable outcomes compared to KMT2A-r? x.gd/BRszp








Inv(3) AML shows resistance to venetoclax plus hypomethylating agents. We identify enhanced BRD4 and MYB pathway dependencies associated with a dormant phenotype, highlighting these as potential therapeutic vulnerabilities. nature.com/articles/s4159…

Our findings expand the current understanding of ferroptosis in MDS pathogenesis. We demonstrate that the SF3B1-BRD9-ALOX5 axis increases susceptibility of hematopoietic cells to ferroptosis through enhanced lipid peroxidation. link.springer.com/article/10.100…




