Excited to share our latest work, “KnowYourCG: Facilitating base-level sparse methylome interpretation” in @ScienceAdvances!
Our computational framework enables efficient functional enrichment for DNA methylation data from diverse assay platforms
science.org/doi/10.1126/sc…
DNA methylation goes spatial! Introducing Spatial-DMT: a technology that co-profiles DNA methylation and transcriptome in the same tissue section. A fantastic collaboration with @zhouwanding lab. Kudos to Chin Nien Lee @ChinNLee2021 and Hongxiang Fu! biorxiv.org/content/10.110…
New paper: we developed Methylation Screening Array (MSA)–a scalable tool to dissect DNA methylation in large cohorts. By profiling 5mC & 5hmC, we uncover trait- and cell-type-specific cytosine mod signatures across tissue, aging. doi.org/10.1016/j.xgen…#Epigenetics#EWAS#5hmC