Hugues Nury

Happy Sunday to all! This morning, we are excited to share Chase’s work developing a simple, scalable method to assemble 100s-1000s of custom genes from oligo pools using standard lab tools! (Small 🧵 below)

Happy to share our paper in @NatureSMB, led by @uriellopezs and Lachlan Munro. We are studying how the antidepressant vortioxetine acts on serotonin 5-HT3 receptors in rodents and humans. rdcu.be/dGv49

Very excited and proud to see the first manuscript of the Wild Team on bioRxiv. If you have ever wondered how the long heparan sulfate polysaccharide chains on the human cell surface are generated, check out our cryo-EM structure of the EXT1-EXT2 complex: biorxiv.org/content/10.110…

Ottawa is beautiful in May - great time for a ligand-gated ion channel meeting: event.fourwaves.com/jointbsc2022iu…

🦠🥼🧪 JOB ALERT 🇫🇷🔬🇪🇺 Join us for an exciting 2-year post doc position ! “Structure function study of a tripartite efflux pump from the ABC superfamily, in its lipid environment”, spread the word ! umr7099.ibpc.fr/apply-for-fell… bit.ly/3o2mYIB euraxess.ec.europa.eu/jobs/734601

- ET MOI JE VOUS DIS QU'ON N'A PAS ASSEZ DE RECUL !!!

The probability of any receptor being a drug target for COVID, over time, tends towards 1. It took 1.5 years but finally my beloved serotonin 5-HT3 receptor is added to the list... 😁

Structural biology PhD position open in our lab, to understand how ligand-gated ion channels operate. Please RT.

@RyanHibbs10 👏 Waouh! Congratulations! How many years in the making?

Please RT: @Caillaud_MC and myself are looking to hire 4 postdocs and 1 PhD student in the frame of ANR and ERC funded projects to work on membrane lipids and development @RDPlab @ENSdeLyon live imaging, super-resolution, single molecules, optogenetics ens-lyon.fr/RDP/SiCE/Home.…

I am happy to announce that we have funding for a new postdoc position in my lab. If interested, please see ad Postdoctoral Fellow in Neuroscience lab job with Icahn School of Medicine at Mount Sinai New York City, New York (US) neurojobs.sfn.org/job/27911/post… #jobs

Slice in an ongoing #CryoEM classification. The outer circle is a lipid nanodisc density. Seems like the protein inside is happy to be there.

La virologie est un sport de combat – Université Ouverte universiteouverte.org/2020/09/19/la-…

I am happy to see our paper in Press! This work provides evidence of a cross-talk between SLC20A2 and XPR1 in the regulation of cellular phosphate homeostasis. Alteration of this interplay likely contributes to Primary Familial Brain Calcification. jbc.org/cgi/content/lo…

STATEMENT BY THE @ERC_research SCIENTIFIC COUNCIL erc.europa.eu/news/resignati…

@ProfKalium My daughter cut mine last weekend. Curiously it was noticed in every video meeting I attended since then...

I would quite literally trust my wife with my life (#NHS hero) but do I trust her enough to cut my hair? 🤔 #lockdownconundrum

Coordinates to be released with the next PDB update, please DM for links in the meantime

First preprint (and tweet)! Binding of palonosetron + other antiemetics to the serotonin 5-HT3 receptor. CryoEM and simulations. biorxiv.org/content/10.110… (Please note: same topic, last summer, similarly cool granisetron-bound structure from @Chakrapani_lab @sandipbasak21)