Mast Cell & Lung Immunology Reseach lab

Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors - Journal of Allergy and Clinical Immunology jacionline.org/article/S0091-…

Our paper about how mast cells contribute to T-cell accumulation in the bronchoalveolar space in mice with IL-33-induced airway inflammation is finally publish, congratulations to all the authors, specially @abigail1049 onlinelibrary.wiley.com/doi/10.1111/im…

Mast cells contribute to T‐cell accumulation in the bronchoalveolar space in mice with IL‐33‐induced airway inflammation - Alvarado‐Vazquez - Immunology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/im…

Join us for the IES August Webinar focusing on the Clinical Aspects of Eosinophilia 🩺 🗓️ Date: Wednesday, August 7, 2024 🕘 Time: US Eastern: 9:00 am – 12:00 pm CET: 3:00 pm – 6:00 pm IST: 6:30 pm – 9:30 pm Secure your spot now: eosinophil-society.org/webinars/august

So happy - thanks to all amazing past and present group members 🙏

I am so grateful and happy for the recognition our work - A special thanks to all talented previous and present group members for all the hard work 🙏

In celebration of #WorldAsthmaDay celebrated on the 7th of May 2024, we would like to highlight recent research on asthma. The below research articles can be accessed by everyone free of charge: 1. Zhao XO, Melo FR, Sommerhoff CP, Paivandy A, Pejler G. Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells. Allergy. 2024;n/a(n/a). doi.org/10.1111/all.16… 2. Won J, Jo A, Kim S, Shin H, Kim HJ. Distinct dampening of IL-33 following inhalation of interferon-lambda in the respiratory epithelium of in vivo asthma. Allergy. 2024;n/a(n/a). doi.org/10.1111/all.16… 3. Voskamp AL, de Jong NW, Jochems SP, Ozir-Fazalalikhan A, van Hengel ORJ, van der Vlugt L, et al. Early expansion of allergen-responsive LAP(+) B regulatory cells in allergic rhinitis but not in allergic asthma subjects during allergen immunotherapy. Allergy. 2024;79(4):1060-4. doi.org/10.1111/all.15… 4. Smolinska S, Popescu FD, Izquierdo E, Antolin-Amerigo D, Price OJ, Alvarez-Perea A, et al. Telemedicine with special focus on allergic diseases and asthma-Status 2022: An EAACI position paper. Allergy. 2024;79(4):777-92. doi.org/10.1111/all.15… 5. Smilnak GJ, Lee Y, Chattopadhyay A, Wyss AB, White JD, Sikdar S, et al. Plasma protein signatures of adult asthma. Allergy. 2024;79(3):643-55. doi.org/10.1111/all.16… 6. Santos AF. Is there a direct link between skin barrier dysfunction and asthma? Allergy. 2024;n/a(n/a). doi.org/10.1111/all.16… 7. Rick EM, Woolnough K, Richardson M, Monteiro W, Craner M, Bourne M, et al. Identification of allergens from Aspergillus fumigatus-Potential association with lung damage in asthma. Allergy. 2024;n/a(n/a). doi.org/10.1111/all.16… 8. Okunishi K, Kochi Y, Zhao M, Wang H, Nakagome K, Izumi T. Munc13-4 regulates asthma and obesity in mice by controlling functions of CD11c(+) antigen-presenting cells. Allergy. 2024;n/a(n/a). doi.org/10.1111/all.16… 9. Okubo H, Nakayama SF, Ohya Y, Japan E, Children's Study G. Periconceptional maternal diet quality and offspring wheeze trajectories: Japan Environment and Children's Study. Allergy. 2024;79(2):393-403. doi.org/10.1111/all.15… 10. Odling M, Lagercrantz B, Goksor E, Sandelowsky H, Janson C, Kull I. Transitional care of adolescents and young adults with asthma and allergy-The healthcare professional perspective. Allergy. 2024;n/a(n/a). doi.org/10.1111/all.16… #Allergy_journal Read more articles published in #Allergy on #asthma here: journalallergy.com/Asthma-Lower-A…

Join us on 8 May for our newest webinar focusing on the Role of Epithelium in Eosinophilic Responses in Allergic Asthma & Chronic Rhinitis/Sinusitis with Nasal Polyposis. Don't miss out, register now at: eosinophil-society.org/webinars/may

We were delighted to host you - warm congrats on your excellent work 🥳

Our paper published in @AllergyEaaci explores the relationship between myeloid progenitors and treatment response to omalizumab. onlinelibrary.wiley.com/doi/full/10.11…

Now out in final form @NatureComms, our recent study reveals how #mastcells can combine PAMP sensing and effector-triggered immunity to differentiate btwn extracellular and invasive enterobacteria. @CvonBeek et al shows you how rdcu.be/dxiSH

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

#Mastcells can combine PAMP sensing with effector triggered immunity and thereby differentiate their response btwn extracellular and invasive #enterobacteria. Thats what the recent findings by @CvonBeek et al tell us. Check out the @biorxivpreprint here: biorxiv.org/content/10.110…

Congratulations to the authors @abigail1049 @Histerika_Haide and others that do not have Twitter

Our latest publication is online #Mastcells Circulating mast cell progenitors increase during natural birch pollen exposure in allergic asthma patients - Alvarado‐Vazquez - Allergy - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/al…

Visit Abigail’s poster P40 now #WIRM

Great science #WIRM

Improve science communication with non-scientists: Combat misinformation by effectively discussing science with the public. Find valuable tools and tips at bit.ly/3kIb7w5. #AwardsAAI #CareersAAI

A protein found in human lungs prevents infection by flu viruses from birds – but mutations in the viruses’ nucleoprotein allow them to escape this inhibition and spill over into humans. go.nature.com/3Ntg9f1

Are you an early career immunologist working in 🇮🇸 🇩🇰 🇸🇪 🇳🇴 🇫🇮 and #SSI member? 👉 Join ySSI scandinavianimmunology.nu/about-yssi/ @yi_SSI @SSI_immunology @FinnSocImm @NSImmun @y_efis #SSI2023