Müschen Lab

304 posts

Müschen Lab banner
Müschen Lab

Müschen Lab

@MuschenLab

B-cell dynamics, oncogenic signaling in B-cell malignancies @YaleUniversity. Since January 2026 @muschenlab.bsky.social

New Haven, CT 가입일 Ocak 2021
281 팔로잉767 팔로워
Müschen Lab 리트윗함
Science Signaling
Science Signaling@scisignal·
A signaling loop centering on the protein CD25 sustains the growth of acute leukemias such as #AML and #B-ALL by fine-tuning the activity of oncogenic tyrosine kinases, according to a new study. @MuschenLab @Yale scim.ag/4rMXddQ
Science Signaling tweet media
English
1
3
9
983
Müschen Lab
Müschen Lab@MuschenLab·
Yale Study Identifies a New Class of Drug Targets for Aggressive Leukemia m.yale.edu/dfyw
English
0
1
7
589
Müschen Lab
Müschen Lab@MuschenLab·
On this week's cover of Science Signaling. Congratulations to Ruifeng Sun and Jaewoong Lee, who led this effort! Dynamic feedback control of oncogenic tyrosine kinase signaling in acute leukemia | Science Signaling science.org/eprint/ZZKJPHH…
English
1
2
10
890
Müschen Lab
Müschen Lab@MuschenLab·
Beta-catenin promotes cancer cell growth but B-cell leukemia cells, unexpectedly, depend on its efficient degradation. Our paper out today in @naturecancer, shows how this dependency could be leveraged for the benefit of patients with B-ALL.👇 nature.com/articles/s4301…
Müschen Lab tweet media
English
3
8
36
2.5K
Müschen Lab
Müschen Lab@MuschenLab·
👇In a few weeks, the Samir Zaidi Lab will open at Yale. Exciting and important science and a generous and supportive mentor - phenomenal opportunity for future graduate students and postdocs with an interest in lineage plasticity and drug resistance in cancer.
Samir Zaidi, MD, PhD@samirzaidi

Fifteen years ago, my wife, Salimah, and I met as graduate students at @Yale in New Haven. Now, in a full-circle moment, I’m thrilled to share that I’ll be joining the @YaleCancer and @ynhhealth to launch my independent lab in March 2025! @samirzaidi I’ll be based in the Center of Molecular and Cellular Oncology and look forward to collaborating with incredible scientists like @BraunMDPhD, @ishizukalab, @S_J_Aitken, #CarolineMlynarczyk, #FrederickWilson and many others, under the leadership of @MuschenLab. I’m deeply grateful for the invaluable mentorship at @MSKCancerCenter ––from #CharlesSawyers @SawyersLabMSKCC, #MichaelMorris, @DrRosenbergMSK —who have guided me along this path. This transition wouldn’t have been possible without the unwavering support and vision of @DrEricWiner. His leadership made Yale feel not just like an exciting scientific home, but a truly warm and welcoming community—one that I can’t wait to be a part of. Excited to continue seeing patients in my clinic at @YaleCancer, and of course, to introduce our two boys to some legendary New Haven pizza!

English
3
0
16
2.4K
Müschen Lab
Müschen Lab@MuschenLab·
Welcome back to Yale, Samir. So glad to have you joining us!
Samir Zaidi, MD, PhD@samirzaidi

Fifteen years ago, my wife, Salimah, and I met as graduate students at @Yale in New Haven. Now, in a full-circle moment, I’m thrilled to share that I’ll be joining the @YaleCancer and @ynhhealth to launch my independent lab in March 2025! @samirzaidi I’ll be based in the Center of Molecular and Cellular Oncology and look forward to collaborating with incredible scientists like @BraunMDPhD, @ishizukalab, @S_J_Aitken, #CarolineMlynarczyk, #FrederickWilson and many others, under the leadership of @MuschenLab. I’m deeply grateful for the invaluable mentorship at @MSKCancerCenter ––from #CharlesSawyers @SawyersLabMSKCC, #MichaelMorris, @DrRosenbergMSK —who have guided me along this path. This transition wouldn’t have been possible without the unwavering support and vision of @DrEricWiner. His leadership made Yale feel not just like an exciting scientific home, but a truly warm and welcoming community—one that I can’t wait to be a part of. Excited to continue seeing patients in my clinic at @YaleCancer, and of course, to introduce our two boys to some legendary New Haven pizza!

English
0
0
3
669
Müschen Lab 리트윗함
Sirpa Leppa
Sirpa Leppa@LeppaSM·
Leo Meriranta @Merijellona is defending his PhD thesis “molecular cross-section of high/risk #DLBCL” today. It is an honor to chair and enjoyable to listen high level scientific discussion lead by Dr Dan Hodson. Thank you Dan, well done Leo!
Sirpa Leppa tweet media
English
1
1
36
1.4K
Müschen Lab
Müschen Lab@MuschenLab·
Congratulations, David!
English
0
0
3
774
Müschen Lab
Müschen Lab@MuschenLab·
Wonderful to be hosting Michael Reth @theNASciences , who discovered the ITAM and pioneer in immune receptor signaling. Thank you for an inspirational seminar @YaleIBIO and private brainstorming session over breakfast.
Müschen Lab tweet media
English
0
1
24
1.5K
Müschen Lab
Müschen Lab@MuschenLab·
@KevinWNg Very cute picture of Clovis. I admire how he is always happy and with shining fur (I think biomarker of dog happiness), not a small feat in Manhattan. Our basset hound passed away a few years ago, hoping to not be dogless for much longer.
English
0
0
0
68
Müschen Lab
Müschen Lab@MuschenLab·
@LindaCPhD This is what I learned from Christian: small grants add up and we should appreciate them. I am glad to see that both of us are following Christian's philosophy!
English
1
0
1
23
Müschen Lab
Müschen Lab@MuschenLab·
Congratulations, Uli, taking PU.1 research to a whole new level.
Uli Steidl@SteidlUli

Very happy and proud to see this study on PU.1 transcription factor "redistribution" and its mechanistic implications out in @NatureGenet today. Huge congrats to lead author @SamuelJohnTayl1! (recruiters watch out: Sam is on the faculty job market now...!). A big thank you also to the entire collaborative team including the twitterless Gregory Poon and Kristy Stengel! @EinsteinCellBio @Einstein_SCI @EinsteinMed

English
1
0
4
621