Tsiairis Lab

Ever wondered how a tiny Hydra blob figures out where its head goes? Turns out, it's not just chemistry — it's feeling the stretch! Check out 👉 Mechanochemical patterning localizes the organizer of a luminal epithelium science.org/doi/10.1126/sc… #Hydra #morphogenesis #biophysics

Now in @Dev_journal: Researchers in the @TsiairisLab discovered how Hydra cells decide to form stinging tentacles or an anchoring foot, revealing key rules of body patterning. Read more at fmi.ch/news-events/ar…

Ever wondered how metabolism regulates embryonic development? Our recent work demonstrates that metabolism has a signaling module controlling the tempo of embryonic axis segmentation. science.org/doi/10.1126/sc…

@jarofrnc @TsiairisLab Read the Research Article “A transcription factor toggle switch determines differentiated epidermal cell identities in Hydra” here: journals.biologists.com/dev/article/15…

Hydra body axis balance: a fight between two transcription factors This Research Highlight showcases the work from Jaroslav Ferenc @jarofrnc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios Tsiairis @TsiairisLab journals.biologists.com/dev/article/15…

How does the #embryo build the backbone? We found that blocking a tiny molecular switch, Rac1, slows the #segmentation clock, and alters the size of spine segments. This could explain why people with #VACTERL syndrome have spinal defects…#preprint 👉 biorxiv.org/content/10.110…

Just planted in Development 🌳 A transcription factor toggle switch determines differentiated epidermal cell identities in <i>Hydra</i> forest.biologists.com/landscape/?id=…

Celebrating our award winning trainee talks from the recent ISRB Conference in Madison given by Daniela Münch, Anish Bose and Lauren Connolly, and proudly sponsored by Development @Dev_journal and Experimental Cell Research.

We're hiring! Our IT Team is looking for a Linux Systems Engineer to support scientific computing and big data management. Apply here: fmi.ch/education-care…

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: fmi.ch/education-care…

In our latest preprint, we reveal a surprising homeotic transformation where Hydra's foot turns into a tentacle! 🧬🔬 How and why does this happen? Find out now! 👇biorxiv.org/content/10.110…

🔬✨ New insights into tissue regeneration! Our study uncovers a novel mechanochemical mechanism in Hydra, revealing how mechanical forces and Wnt signaling work together to create intricate tissue patterns. #Cnidarians #Hydra #Biology #Regeneration biorxiv.org/content/10.110…

It is a great meeting in Freiburg celebrating a pivotal moment in embryology! Behind this Nobel Prize are three unsung heroines: Hilde Mangold, Ethel Browne, and Hydra viridissima… #spemannmangold2024 #Hydra

📢We're now accepting applications for our #PhD and #MDPhD programs! 🧬Join us in Basel, Europe's top hub for the #LifeSciences, and unleash your potential in a vibrant, international and supportive environment. 📅 Apply by November 15 at: fmi.ch/education-care…

@SonnenKatharina Excellent work! 🌟 Essential reading for anyone exploring the impact of time on tissue patterning.

Ever wondered how stem cells ensure a balance between cell fates in the gut?⚖️Turns out, they’ve got rhythm!🎶Our latest research reveals that NOTCH-driven oscillations regulate stem/progenitor cell abundance and specify secretory subtypes. Check it out: biorxiv.org/content/10.110…

Interested in applying for a fellowship to do a PhD @unil with my lab (bacterial synthetic biology) as a host? Send me a CV and a motivation letter till September 6th! unil.ch/ecoledoctorale…

🎉 Exciting news! Today marks the official opening of our new FMI building on the Novartis campus. This move strengthens our collaboration and commitment to pioneering biomedical research. Here’s to new horizons and shared innovation! 🏢🔬 #FMIOpening #Novartis #Innovation

Had a fantastic time at #Cnidofest2024! Our lab enjoyed sharing our research and connecting with fellow cnidarian enthusiasts. Thanks to everyone for making it a memorable event! 🪼🔬  #Cnidarians #Hydra

Check out our latest preprint on how Hydra cells regenerate missing parts. You might need to update your textbook knowledge on regeneration… biorxiv.org/content/10.110…