Uffe H. Mortensen's Lab

Our #OpenAccess "CRI-SPA: a high-throughput method for systematic genetic editing of yeast libraries" paper is now available at @NAR_Open. 👇 doi.org/10.1093/nar/gk…

New tool for filamentous fungi by @UHMortensenLab doi.org/10.1093/nar/gk… "RoCi—a single-step multi-copy integration system based on rolling-circle replication" 👇🍄🔧⚙️

Latest from @UHMortensenLab …robialcellfactories.biomedcentral.com/articles/10.11…

The key plasmids from our Pichia tools paper academic.oup.com/femsyr/article… are now available @Addgene addgene.org/Uffe_Mortensen/ please share the news 🧑‍🔬🧬

Our preprint "RoCi - A Single Step Multi-Copy Integration System Based on Rolling-Circle Replication" is online at @bioRxiv_synbio @biorxivpreprint doi.org/10.1101/2024.0…

Our #OpenAccess oligonucleotide-based gene engineering toolbox for Pichia is now published in @FEMSmicro Yeast Research 👇doi.org/10.1093/femsyr…

"Oligonucleotide-based CRISPR-Cas9 toolbox for efficient engineering of Komagataella phaffii" is now online @biorxivpreprint 👇

I'll be giving a seminar tomorrow at @DTUtweet as part of their Biotech Lifelong learning series. I'll be talking about 'Rethinking omics in cell line design and engineering'. Join in person or online if you're interested dtu.events/seminarseries

CRI-SPA tool in combination with biosensor allows high-throughput genome-wide identification of targets that improve cis-cis-muconic acid production in yeast doi.org/10.1101/2023.0…

Whole genome sequence characterization of Aspergillus terreus ATCC 20541 and genome comparison of the fungi A. terreus -in @SciReports -with @UHMortensenLab nature.com/articles/s4159…

Check out this cool job in Denmark. Join us on the hunt for plastic degrading enzymes at @DTUbioengineer together with fellow Boy band members at Enzync @UHMortensenLab and Peter Westh.efzu.fa.em2.oraclecloud.com/hcmUI/Candidat…

Check our in vivo DNA assembly toolbox for simple genetic engineering of filamentous fungi. We show construction of vectors, complex multipurpose gene-targeting substrates and constructs for #CRISPR based marker-free gene editing directly in fungi 👇 pubs.acs.org/doi/10.1021/ac…

Happy to share our latest work, CRI-SPA – a mating based method for high-throughput genetic modification of yeast strain libraries! Many possible applications for #sysbio and #biotech. Thanks to all involved @DTUbioengineer @DTUBiosustain. See👇 biorxiv.org/content/10.110…

Really looking forward to this exciting collaboration!

Our #CRISPR plasmid collection in @Addgene just got updated, see addgene.org/Uffe_Mortensen/ #cellfactories #yeast #Synbio

A great day in the lab with two papers driven by former PhD student Yaojie Gou out in ACS Journals :-) doi.org/10.1021/acs.jn…, doi.org/10.1021/acs.or…

Check out an addition to our #CRISPR toolset doi.org/10.1093/synbio… An interesting non-conventional yeast from CTG-clade Debaryomyces hansenii can now be efficiently engineered. Published in @OUPSynBio #Synbio #OA #Biotechnology.

and the link: doi.org/10.1093/synbio…

Today I am presenting the latest developments from our lab @ICY15_Vienna. Tune in!

Nice collaboration between @DTUtweet Food and @DTUbioengineer just got published. Take a look! "Authentication of vanillin ex glucose – A first study on the influence of the glucose-source on the δ13C and δ2H value" sciencedirect.com/science/articl… #Cellfactories #Vanillin