Zemper Lab

Check out the latest preprint from our lab - a tour de force in colon developmental biology by Ph.D candidate @hopton_rachel !! Rachel’s thesis work gives us a close-up view of colon epithelial development and stem cell clonality! Congrats Rachel!

TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase period (minutes to hours) and then 1-minute APEX tagging in the destination compartment. Proteins tagged by both enzymes are enriched with streptavidin and anti-fluorescein antibody, and identified by mass spec. We explore 4 intracellular and intercellular applications of TransitID: - discovery of locally translated mitochondrial proteins (translated at OMM, then imported into mito matrix) - mapping proteins whose cytoplasm-to-nucleus shuttling is dampened by stress - discovery of proteins that transit between nucleolus & stress granules during stress & stress recovery - analysis of proteins that traffic intercellularly bw tumor cells & macrophages Work of amazingly talented co-first authors @WeiQinChemBio and @CheahJoleen, and collaborators Steve Carr @namude & Paul Taylor authors.elsevier.com/a/1hKLcL7PXmcqA

It is unbelievable to receive a perfect score of 10 for my K99/R00 application, given my initial submission was not even discussed. I felt very disappointed back then and thought I wouldn't have a chance. I hope my n=1 case could encourage other applicants in similar situations.

It’s been an exciting couple of weeks! Last Tuesday I defended my PhD dissertation from @ZempLab!! Today I was able to participate in the hooding ceremony! It’s been a wild ride and I’m not quite sure what’s next, but I am excited to see where this journey takes me!

Dr. Hopton walked across the stage and received her PhD hood today! Congratulations 🍾🎈🎉 @hopton_rachel ! @uoregon @UO_Research @UOBiology

Re: the images- “she’s a professional,” -as noted by one very esteemed committee member!

Long-time @ZempLab Research Tech @NatPellitier is officially a physician! Dr.Pellitier graduated @OHSUSOM yesterday and will continue in her #familymedicine track stay- ahem- slaying at OHSU! Congratulations Doc!

MHCII expression by intestinal epithelial cells: Markus Geuking reviews decades-old data and recent findings on antigen presentation by IECs during #colitis mucosalimmunology.org/article/S1933-…

Congratulations to the 2023 AGA Institute Council award recipients! 🎉 ▪️ Suyavaran Arumugam, PhD ▪️ Saeed Soleymanjahi, MD, MPH ▪️ Karthik Goli We were thrilled to recognize these individuals during this year's @DDWMeeting in Chicago. Read more: ow.ly/4vIc50OEx2o.

Welcome to @AmerGastroAssn Council!

Drumroll, please… @hopton_rachel is defending her @UOBiology PhD one week from today! @uoregon @UO_Research #zemplab #colondevelopment

Personal statement in a #biosketch. Talk about yourself in the 3rd person?

HPHY News: Check out the latest publication from Dr. Adrianne Huxtable exploring the effects of prenatal opioid exposure @FrontPhysiol @uocas @UO_Research around.uoregon.edu/content/how-pr…

To address the growing need for NIL legal assistance, the Business Law Clinic, a class offered at the University of Oregon School of Law, provides student clients free NIL contract review and education. around.uoregon.edu/content/law-sc… @Oregon_Law

UO Science PhD students trying to study things in complex environments, consider applying to the UO-NRT! Info session on Wednesday, applications due 5/30. @uoCHandBIC @UoPhysics @UOBiology @UOKnightCampus @UOVolcanology @HphyUo

Only a few more hours until the annual #DucksGive begins! Support your favorite department in the College of Arts and Sciences by giving Thursday, May 18. ducksgive.uoregon.edu/cas

Jason and Nissa Pellegrini made a generous $11,000 gift to support @UO_KCGradIntern scholarships! This supports students in the accelerated master’s program at #KnightCampus. The Pellegrini's gift unlocks dollar-for-dollar for #DucksGive donations TODAY! fal.cn/3ylQ0

It’s giving day! Help us fly forward and reach the largest number of gifts out of any department in CAS #ducksgive

CONGRATULATIONS to @KevinTMueller who successfully defended his Clark Honors College and @UOBiology Thesis today! To paraphrase a committee members, “His depth of knowledge is impressive!” We couldn’t agree more. Good luck next year at @BrighamWomens next year!!! #GITwitter 🥳

Check out ⁦@AmerGastroAssn⁩ #IMIBD #PGDB Research Forum on Pediatric #IBD Clinical & Translational Studies today at 2 pm‼️ ⁦@DDWMeeting⁩ ⁦@Realcecum⁩ ⁦@ZempLab⁩ #DDW2023

You're invited! oSTEM is hosting a panel featuring grad students who will share their experiences in grad school, how to apply, and more - Monday, May 8, from 5-6 pm in EMU 119.