Cameron Dale MacQuarrie

All raw microscopy data are on BioImage Archive and image processing tools are on GitHub. If you've seen anything like this in algae or other microbes on rich media, we'd love to hear from you. [9/9]

What triggers this? What are the wisps? Is it adaptive or a stress response? We don't know yet. We're sharing these observations now because they're unexpected and we want feedback — similar phenomena in other systems, mechanistic ideas, experimental priorities. [8/9]

New pub from @ArcadiaScience 🧵 We found that C. smithii — a freshwater green alga — undergoes wild morphological transformations when grown on Marine Broth. Huge cells with mysterious wisp-like appendages. Here's what we saw. thestacks.org/publications/o… [1/9]

You can also download the poster at bit.ly/evo-val and let me know your thoughts here!

Come see me at my poster at #CellBio2025 to learn about how we’re validating some of our new technologies at @ArcadiaScience!

🦠 @ArcadiaScience is hiring a cell biologist to join our team and phenotype diverse organisms! I’m at #CellBio2025 this week if you want to learn more, but if it sounds interesting apply!! If this isn’t a perfect match, check out our other roles. App👇 jobs.lever.co/arcadiascience…

@ASCBiology Seems like fun? We're hiring! arcadiascience.com/careers

zoogle.arcadiascience.com told us Chlamy is a great model for ADA1 — so we tried it! Come chat about it: Sunday Dec 7, 2:15–3:45 pm (digital poster, near @ASCBiology booth) Monday Dec 8, 2:15–3:45 pm (paper poster, B538)

Excited to share some new work from @ArcadiaScience at #CellBio2025! We’re using Chlamydomonas reinhardtii as a rapid in vivo platform to model ADA1 deficiency and test computationally designed therapeutic ADA1 variants. Check out the poster here: bit.ly/chlamy-ADA

Gonna miss my first @ASCBiology meeting #CellBio2025 in 15 years 😱. However, some scientists from @ArcadiaScience are going and we have job openings (this crowd is particularly well suited for the evolutionary cell biologist role) so please seek out @BiggeBrae and @cdmacquarrie! arcadiascience.com/careers

we recently did our biggest icebox so far @ArcadiaScience -- we made the call to wind down our first/longest running start-up Trove. read about why & what we learned (and technical resources we released!). Quick 🧵👇 research.arcadiascience.com/pub/perspectiv…

Phenotypes often arise from linear + nonlinear genetic relationships. Neural networks should be great at modeling this. Results are mixed. Why? research.arcadiascience.com/pub/result-gp-… [1/11]

Biological foundation models have hit a plateau. Scaling isn't working as expected. Foundational concepts from evolutionary biology could have predicted this: 🧵 research.arcadiascience.com/pub/idea-phylo… [1/9]

📢 Hey #Evol2025 attendees, we’re hiring! If you’re interested in #careers at Arcadia, swing by our free mixer upstairs at The Globe today from 5:30 to 7:30. It’s a 7-minute walk from the Classic Center and drinks are free 🍻 jobs.lever.co/arcadiascience