Dr. Udayanath Gouda

The Brain doesn't care about your intention It's only care about your repetition Repeat what you want to remember Repeat Who you want to become ❤️🙌 #MedX

Reason - due to high systolic and low diastolic BP #MedX

Quincke's sign seen in AR 🧵✨

3. Primary dengue infection ⬇️ Ab formed for primary infection serotype ⬇️ During 2nd infection Ab from 1st time will bound with the 2nd time infected serotype ⬇️ More severe #MedX

2. Secondary dengue infection is more severe . Why ?? 👇 This is called ADE ( antibody dependent enhancement)

1. Dengue antibodies are type specific ( single serotype Ab can only protect to that serotype in future ) 🧵👇

The moment I received this CCTV picture from GMC Bhavnagar (Gujarat), my mind froze for a moment thinking how mentally and physically devastated these Orthopaedic surgery resident doctors must have felt at this moment when they were made a murgha openly in the Operation Theatre. Every NEET UG and PG aspirant and their parents must watch this to open their eyes regarding this over glorified profession in India .

Myerson's sign #MedX

Pedal edema #Stemmersign #MedX #MedTwitter

3. Common SGLT2 inhibitors include: Empagliflozin Dapagliflozin Canagliflozin Ertugliflozin #MedX #MedTwitter

2.

MOA of SGLT2i in heart failure 🔥 🧵 1. #MedX

📍Under conditions like heart failure - ketone bodies utilised as fuel as requires less metabolic processing Furthermore , it's a sympathetic overdrive condition, lipolysis occurs in response to increased catecholamines Lipolysis -> fatty acids -> ketone bodies hence used by❤️

📍During myocardial ischemia(MI) - it utilises glucose as fatty acids require more oxygen to metabolise, and the heart is already in survival mode with deficit of oxygen Per molecule of oxygen consumed - glucose yields 6.3 ATP - fatty acids yield 4.1 ATP

@TrackYourHeart .

A patient was admitted with a stroke. What is the reflex and what does it imply?

Stunned myocardium - Acute brief ischemia, heart is shocked However flow is restored to heart either spontaneously/ through interventions Still left ventricular dysfunction is noted Takes days to weeks for the heart to recover

Screening age has been lowered to 45 And stool based test are added for screening modalities. ✅ Stool based test - mt-sRNA and ng-mt-sDNA #MedX #MedTwitter

Uhthoff’s phenomenon is seen in: #MedX Uhthoff’s phenomenon :- Neurological symptoms worsen with heat.

💠 Temprature dependent conduction block aka uhthoff's phenomenon seen in MS Why ⁉️ 1️⃣Increased temperature alters sodium channel kinetics and shortens action potential duration 2️⃣demyelinated fibers highly sensitive to physiological changes that leads to conduction block and worsen the previously affected neurological deficit 💯✨

"Heart ❤️ is an omnivore" Heart utilised different substrates as fuel under different conditions 📍Under normal circumstances - Fatty acids as ⛽ , most energy dense 1 molecule yields as much as 106 Atps compared to glucose that yield 32 atp per molecule