Paritosh Garg

23 posts

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Paritosh Garg

Paritosh Garg

@docparitosh

Budding hematologist and bone marrow transplant physician

Gurugram 가입일 Nisan 2017
161 팔로잉11 팔로워
Paritosh Garg
Paritosh Garg@docparitosh·
@rajshekharucms Totally agreed 💯. We use bispecifics in penta class refractory myeloma patients before CAR T cell therapy at our center in India with very good response rates and PFS rates
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Raj Chakraborty
Raj Chakraborty@rajshekharucms·
With 85% CD38-refractory, we are seeing at least a similar (if not better) PFS with single-agent Teclistamab when compared to Cilta-cel arm of CARTITUDE-4, which had just ~25% CD38-refractory. These results, along with MajesTEC-3, challenge the dogma of “CAR T before BsAbs” in all for early relapse. Looking forward to the manuscript! #ASCO26
Samer Al Hadidi, MD,MS,FACP@HadidiSamer

#mmsm #ASCO26 MajesTEC-9 ➡️Tec vs. PVd/Kd (1-3 prior lines of therapy) ➡️Len refractory: 80%; anti-CD38 refractory: 85% ➡️median F/U ~1.5 yrs ➡️18-mo PFS rate: 70% vs 27% ➡️improved OS with Tec vs PVd/Kd (HR: 0.60), even with >2/3 of pts getting BsAb or CAR-T as subsequent treatment 🛑Gr 5 TEAEs (6.5% vs 3.5%)-higher with Tec vs PVd/Kd 🛑Gr 3/4 infections were higher with Tec vs PVd/Kd (42% vs 29%) Teclistamab single agent in anti-CD38 refractory is a great option to have in early relapsed myeloma asco.org/abstracts-pres…

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Barb Kennedy
Barb Kennedy@b_2boysmom1310·
@rajshekharucms @FDAOncology I don’t understand why patients would want a BsAb b4 CAR-T. Patients/care givers truly need a drug holiday. We forgot this. BsAb should B after CAR unless they completely are not a candidate for CAR. Cost has to be less over course of therapy. Who has a cost model?
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Raj Chakraborty
Raj Chakraborty@rajshekharucms·
Registrational trials of Bispecific Antibodies in #MultipleMyeloma ought to be designed as fixed-duration going forward. Continuous BsAb treatment until progression is unsustainable, especially in earlier lines of treatment. @FDAOncology should require sponsors to design either as fixed duration or include a fixed duration comparator arm in registrational trials. While the infection rate drops after 1st 6-9 cycles, it never plateaus with continuous therapy!
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Paritosh Garg 리트윗함
Coinvo
Coinvo@Coinvo·
🇺🇸 WARREN BUFFETT: "I can end the U.S. deficit problem in 5 minutes." "Just pass a law that any time there's a deficit of more than 3% of GDP, all members of Congress are ineligible for re-election."
Coinvo tweet media
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Paritosh Garg
Paritosh Garg@docparitosh·
@rajshekharucms It was wonderful listening to you , learning new insights into the intricacies of management of amyloidosis
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Paritosh Garg
Paritosh Garg@docparitosh·
@narendramodi sir need to look into the complaints of decreased mileage and more vehicle breakdown with 20% ethanol blending
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Paritosh Garg
Paritosh Garg@docparitosh·
@nsitharamanoffc discontinue 500 rs note and provide indexation benefit on latest LTCG rates to boost formal GDP of country and curb corruption
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Paritosh Garg
Paritosh Garg@docparitosh·
@narendramodi explore India s tourism potential . Restore and aesthetically clean all old monuments.provide all inclusive packages to international tourists. Promote tourism at priority levels.
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Paritosh Garg
Paritosh Garg@docparitosh·
@narendramodi need to use Artificial Intelligence in tenders, permissions, and other aspects of policy approvals in government for actually improving ease of doing business index in India
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Paritosh Garg
Paritosh Garg@docparitosh·
@nsitharaman need to use Artifical Intelligence in tenders, permissions, and other aspects of policy approvals in government for actually improving ease of doing business index in India.
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Paritosh Garg
Paritosh Garg@docparitosh·
@AmitShah Besides terrorists , punish those who hosted them too. Connections of terrorists should also not be spared. This is the only way forward
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Amit Shah
Amit Shah@AmitShah·
Anguished by the terror attack on tourists in Pahalgam, Jammu and Kashmir. My thoughts are with the family members of the deceased. Those involved in this dastardly act of terror will not be spared, and we will come down heavily on the perpetrators with the harshest consequences. Briefed PM Shri @narendramodi Ji about the incident and held a meeting with the concerned officials via video conferencing. Will shortly leave for Srinagar to hold an urgent security review meeting with all the agencies.
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Paritosh Garg
Paritosh Garg@docparitosh·
@nsitharaman reduce LTCG on shares and property to 5% to increase transparency and turnover . GST and increased spending power will take care of estimated shortfall in taxes
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Paritosh Garg
Paritosh Garg@docparitosh·
@narendramodi reintegrate Bangladesh with India granting them full autonomy and managing only their security and external affairs
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Paritosh Garg
Paritosh Garg@docparitosh·
@KremlinRussia_E have mercy on Ukraine and Ukrainian people. They have had enough and got their lesson. And you have ample land . Manage a reasonable truce acceptable to both countries for sake of humanity.
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