Ophthalmology

We are proud to announce the appointment of Bennie H. Jeng, MD, as Editor-in-Chief of our flagship journal, Ophthalmology! aao.org/newsroom/news-…

Predicting Visual Field Loss in Glaucoma Using OCT and Deep Learning: A Comparative Study of U-Net Variants ow.ly/uSOm50Yz9KE #ophthalmology #glaucoma

A Continuous Severity Index for Keratoconus Diagnosis Based on Kolmogorov–Arnold Networks in a Chinese Population ow.ly/LlcY50Yz9Jo #ophthalmology

A 39-year-old patient was referred for an asymptomatic retinal lesion in the left eye. Fundus examination (A) revealed a well-circumscribed, whitish intraretinal mass located along the inferior temporal arcade (white arrow), associated with adjacent preretinal neovascularization (green arrow). Autofluorescence imaging (B) showed a homogeneous, round, hyperautofluorescent lesion, with a raspberry-like heterogeneous intraretinal mass on OCT B-scan (D). Fluorescein angiography (C) revealed homogeneous staining of the lesion, inferior temporal retinal ischemia, and preretinal neovascularization, suggesting a branch retinal vein occlusion secondary to a mechanical mass effect. ow.ly/UvJP50Yz9Hp #ophthalmology #retina

How accurate is ChatGPT in responding to patient questions at a 6th grade reading level vs a 12th grade reading level? Find out in the new Ophthalmology Journal podcast with @rg_mirza and Dr. Angelo Tanna aao.org/education/audi… #ophthalmology #ophthalmologyjournal #podcast #chatgpt #ai #artificialintelligence

Comprehensive Evaluation of ChatGPT’s Diagnostic Accuracy on Image-Based Ophthalmic Case Interpretations ow.ly/M4hb50Yz9Fc #ophthalmology

Over 1 million eyes from the IRIS registry, studied to evaluate features of post–injection endophthalmitisafter the first anti-VEGF injection. Most cases occur 3–8 days post-injection, with risk shaped by geography, smoking, & prior steroids. ow.ly/W8Pg50YCgGv

A 55-year-old healthy man noted 3 days of blurred vision left eye. He denied neck trauma or any type of neck procedure. Visual acuity was 20/25 right eye and 20/40 left eye. Bilateral optic disc edema was noted on examination (A). Magnetic resonance imaging and cerebral angiography confirmed a left external carotid artery-jugular bulb arteriovenous fistula (B, arrows). After coil embolization (C, arrows), the papilledema resolved and was replaced by pallor (D). Spontaneous jugular bulb arteriovenous fistula is a rare occurrence; however, when it occurs can result in elevated intracranial pressure due to cerebral venous hypertension manifesting as papilledema. ow.ly/BMZZ50Yz9AV #ophthalmology

Retinomics as a tool for glaucoma prediction ow.ly/egGC50Yz9xb #ophthalmology #glaucoma

Phacovitrectomy versus vitrectomy for primary rhegmatogenous retinal detachment in phakic eyes: a multicentre propensity-matched study ow.ly/fU1i50YCgCV #ophthalmology #retina

A 36-year-old man was referred for management of a painless mass of the ciliary body. On examination, a nonpigmented conjunctival nodule (A) was present external to a lesion arising in the ciliary body that extended to contiguous choroid (B, ultrasound). Biopsy of the conjunctival tumor revealed histiocytes with phagocytosed lymphocytes (emperipolesis) (C, yellow arrow, ×200). Histiocytes expressed CD68 and S-100 (D, red arrows, ×200) and did not stain for CD1a. BRAF V600E mutation was not present. The diagnosis was extranodal Rosai-Dorfman disease, a rare non-Langerhans cell histiocytosis. ow.ly/mWWi50Yz9uX #ophthalmology

Fundus Autofluorescence as a Sensitive Biomarker of Disease Progression in Bietti Crystalline Dystrophy ow.ly/hMXe50Yz9qO #ophthalmology

Fluocinolone Acetonide Implant as a Baseline Therapy for Diabetic Macular Edema: Results from the Randomized Phase 4 NEW DAY Study ow.ly/xin550YCgAX #ophthalmology

A 61-year-old man presented with obscuration of vision in the right eye due to a slowly progressive, painless lower eyelid swelling of 7 years duration. (A) Oblique clinical photograph showing an 8 × 4 × 3 cm firm-to-hard pedunculated lesion arising from the right lower eyelid with overlying dilated vessels and pinchable skin, causing visual axis obstruction. Best-corrected visual acuity was 20/20 in both eyes. (B) Computed tomography demonstrating a polypoidal soft-tissue lesion with calcifications in the inferior right periocular region. (C) At 1-month postoperative visit the patient was asymptomatic. (D) Histopathology revealed features consistent with chondroid syringoma. ow.ly/o7KS50Yz9pf @VedantS999 #ophthalmology

Read Dr. Jeng’s inaugural editorial from the May 2026 issue of Ophthalmology: aaojournal.org/article/S0161-… #ophthalmology #artificialintelligence #ai

We are proud to announce the appointment of Bennie H. Jeng, MD, as Editor-in-Chief of our flagship journal, Ophthalmology! aao.org/newsroom/news-…

Acute ischemic ocular events are strong warning signs for stroke. In >11K patients from the Truveta Electronic Health Record database, 22.8% had Ischemic Stroke or TIA within 1 year and in 9.4% on the same day. Age, HTN, carotid stenosis ↑ risk ow.ly/jAGZ50YCgy2

Cornea transplant surgery assisted by a microsurgical robot: first case report ow.ly/AJiB50Yz9lm #ophthalmology #cornea

A 55-year-old man presented with progressive vision loss in the right eye (OD). Best-corrected visual acuity was 20/400 OD and 20/20 in the left eye. Anterior-segment examination revealed numerous superficial, centrally located brown deposits OD (A), raising concern for primary corneal melanoma. After fluorescein staining, a retained contact lens with pigmented deposits was identified and removed (B). Microscopic evaluation revealed lightly pigmented reflective fungi on the lens surface (arrows) and penetrating the lens (arrowheads), associated with pigmentation of the lens (asterisk) (C; unstained preparation, ×400). Periodic acid-Schiff stain highlighted fungi (D; ×400). ow.ly/xT4q50Yz9fm #ophthalmology

The May issue of Ophthalmology is out now! Featuring articles on: ✅Acoltremon Ophthalmic Solution 0.003% for Signs and Symptoms of Dry Eye Disease: Results of Phase 3 Pivotal Studies COMET-2 and COMET-3 ✅Efficacy of an Automated Point-of-Care UVC Disinfection System for Reusable Ophthalmic Devices ✅Four-Year Outcomes of Faricimab in Diabetic Macular Edema: Results From the RHONE-X Extension Trial ✅Risk of Glaucoma and Undergoing Glaucoma Surgery in Myopic and Highly Myopic Eyes: A Nationwide Population-Based Cohort Study And much more! aaojournal.org/issue/S0161-64… #ophthalmology

Genome-wide Meta-Analysis for High Myopia Provides Insights into Disease Mechanisms and Reveals a Causal Link to Primary Open-Angle Glaucoma ow.ly/56Kh50YwjtR #ophthalmology #glaucoma