Ashlee Vance
11.9K posts
@ashleevance
Writing at https://t.co/m6EtO60SiY and host of the Core Memory podcast. 2X NYT best-seller. Filmmaker @HBO (Wild, Wild Space) + @Netflix (Don't Die).
These numbers are shocking. It's like we got a new frontier AI model but for the body. Lilly's phase 3 results for retatrutide: > highest dose lost 28.3% of body weight in 80 wks > 70 lbs ave > 45% lost 30% or more of their body weight > 65% on the top dose no longer clinically obese Retatrutide is more dynamic than semaglutide and tirzepatide because it targets three receptors (GIP, GLP-1, and glucagon), versus one and two, respectively. Side effects, on the highest dose (12mg), were higher for retatrutide than tirzepatide (nausea and GI), with an 11.3% drop out rate. The lowest 4mg dose still delivered 19% loss with fewer dropouts than placebo.
Open Tab Ep 3: @ashleevance on new media, getting close to Elon and showing audiences where the world is headed before it gets there. 00:00 "Elon might actually bankrupt me" 00:01:08 George Hotz joyride 00:07:09 Silicon Valley watering hole 00:09:00 They thought I was a woman 00:12:07 Life before and after the Elon biography 00:15:30 Monthly dinners with Elon 00:22:05 "95% accurate" 00:25:00 Elon said "I'm gonna destroy your life" 00:27:02 Kim Dotcom raid 00:27:30 Reconciling with Elon 00:29:49 Getting access to Neuralink 00:31:00 Bryan Johnson documentary 00:33:40 Funding movies 00:35:17 EVE Online 00:36:09 Hello World: Emmy nomination 00:37:18 Audience reach: Substack vs Bloomberg 00:38:39 PR people out of touch 00:40:13 65% of YouTube viewers watching on a TV 00:42:30 Ayahuasca on assignment 00:45:06 "I had the best job in media" 00:45:30 Started media company anyway
Know there are a ton of Kelly Johnson and Skunk Works fans out there. Well, @joshdean66 has just written a tremendous new book about Johnson. And we have an exclusive excerpt up for ya. corememory.com/p/kelly-johnso…
We need to rebrand this company ASAP
