Aydogan Lab

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Aydogan Lab

Aydogan Lab

@AydoganLab

We study principles of biological time control with a focus on the emerging concept of autonomous clocks. Columbia University & HHMI

New York, NY Katılım Kasım 2019
497 Takip Edilen799 Takipçiler
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Aydogan Lab
Aydogan Lab@AydoganLab·
EXCITED to unroll this 🧵 on our new story on the metabolic licensing of animal development... How did we even get here..? shorturl.at/vuCIh Early embryo is thought of a pre-set machine that's set to go once it's fertilized - check out this gorgeous 📽️from Phil Keller!
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Alfonso Martinez Arias
Alfonso Martinez Arias@AMartinezArias·
@AydoganLab Yes but different versions of this one, always from the same lab, have been coming for years without independent confirmation and much to the opposite. Journals should take note
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Eric Betzig
Eric Betzig@Eric_Betzig·
Absolutely. Every major idea I’ve had, and nearly every solution to a roadblock when executing those ideas in the lab, has arisen from long periods of solitude. It’s no mystery - the process of discovery involves winnowing through an infinite thicket of possibilities to find the answer, and any interruption to this reverie crashes the whole edifice of thought to the ground.
Physics In History@PhysInHistory

Nikola Tesla on the importance of seclusion and solitude (1934) ✍️ The mind is sharper and keener in seclusion and uninterrupted solitude. No big laboratory is needed in which to think. Originality thrives in seclusion free of outside influences beating upon us to cripple the creative mind. Be alone, that is the secret of invention; be alone, that is when ideas are born.

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HHMI
HHMI@hhmi_science·
Rising undergrad junior or senior? Last chance to apply! Applications close TOMORROW, Dec. 22, 11:59pm EST. Our 9-week summer research experience includes hands-on lab work, a generous stipend, & mentorship from some of the nation’s top scientists. Learn more & apply at bit.ly/CechFellows.
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Ruben Gonzalez
Ruben Gonzalez@rubenlgonzalez·
The Gonzalez Lab at Columbia University is seeking a scientific leader! Join us in a Research Scientist position, driving single-molecule, structural, and biochemical studies of translation, translational control, and other RNA-based processes. Apply: apply.interfolio.com/176949
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Gunes Parlakgul
Gunes Parlakgul@gparlakgul·
Excited to share I have accepted a tenure-track Assistant Professor position at UC Berkeley, in the department of Nutritional Sciences and Toxicology. The Parlakgul Lab will open in January 2026!🚀 @BerkeleyMetBio @UCBerkeley
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Ekaterina Korotkevich
Ekaterina Korotkevich@eykorotkevich·
Excited to share our new paper! mtDNA mutations contribute to mitochondrial disease and aging only if they rise in abundance. We show that deleterious mutations reach high abundance by hitchhiking on genomes that have a replicative advantage rdcu.be/eugVO
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Aydogan Lab
Aydogan Lab@AydoganLab·
If you're finishing PhD soon and thinking of postdocs, see below! Especially if you're keen on combining biochemistry, imaging and cell biology, we are onto some exciting findings on molecules and mechanisms underlying a cytoplasmic division cycle autonomously of CDKs!!
Aydogan Lab@AydoganLab

#Postdoc opportunity at Columbia U. in New York! We are interested in candidates from biochemistry backgr. & excited about fractionation, purification and reconstitution to study autonomous clocks in the cell cycle, in colab. w/ @Aydinlab at NYU! hhmi.wd1.myworkdayjobs.com/External/job/C…

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Gizem Efe
Gizem Efe@GizemEfePhD·
🚨Thrilled to announce I will be presenting our work at the Cold Spring Harbor Genome Engineering: CRISPR Frontiers Meeting (@CSHL) Aug 12–16! 🧬✨ We're combining cutting-edge in vivo CRISPR strategies with cancer research to uncover how mutant p53 drives metastasis—mutation by mutation. From high-throughput in vivo CRISPR knockout screens to precision base & prime editing, this project dissects tumor evolution at an unprecedented resolution. Our findings underscore the emerging potential of allele-specific treatments in precision oncology. Let’s talk CRISPR, cancer, and innovation! #cshlcrispr25 #CRISPR #p53 #cancerresearch #metastasis #CancerGenomics @cshlmeetings @ColumbiaMed
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Tanentzapf Lab
Tanentzapf Lab@TanentzapfLab·
I think a good rule of thumb is to spend at least as much time thinking about your data as you did obtaining it. It's common for people to spend a lot less time thinking than doing which gives rise to all kinds of problems.
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Elif Nur Firat-Karalar
Elif Nur Firat-Karalar@CytoLabKoc·
I'm pleased to share this work now published in @PLOSBiology! Since our preprint, we've uncovered exciting new links connecting CCDC66 to actin, vesicular trafficking, and Wnt signaling, and revealed how these contribute to CCDC66's ciliary functions. See link below!
Elif Nur Firat-Karalar@CytoLabKoc

New preprint alert! We've uncovered the role of the microtubule-associated protein Ccdc66 in maintaining the stability and disassembly of the primary cilium. Our findings reveal how Ccdc66 depletion leads to unstable cilia and affects signaling pathways like Hedgehog and Wnt.

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Prof. Nikolai Slavov
Prof. Nikolai Slavov@slavov_n·
In case this is not obvious: Expecting to understand and predict human biology based solely on modelling nucleic acids is naive. It’s unrealistic.
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Keşfet

@AMartinezArias @KrunoVuk @institutrb @NatureComms @Alexis_Lomakin @gparlakgul @BerkeleyMetBio @UCBerkeley