Chris Cho

Efficacy for prolonged infusion beta-lactam dosing schemes has been previously described, but there has been less focus on the safety of this strategy! 🆕️🔥 #IJAA Meta-analysis on safety of standard vs prolonged infusion of beta-lactams #IDXposts sciencedirect.com/science/articl…

🌟 MONKEY POX - Potential treatment options academic.oup.com/ofid/article/9…

Check out our ASP Team’s latest newsletter! 💊🦠🆔 #idccm #IDCCM #ASP #AntimicrobialStewardship #IDforMe

New insights into the therapeutic management of Varicella-Zoster Virus meningitis: a series of 123 PCR-confirmed cases ✅ Just Accepted 🔗 bit.ly/4bkqu6V

Yahoo!! Another article to support PO stepdown for Streptococcal bacteremias. Stoked to be a part of this excellent team! academic.oup.com/ofid/article/d…

Things We Do for No Reason™: S. pneumoniae and Legionella urine antigen testing The authors suggest we should never order a S.pneumoniae UAT For legionella UAT, it could be considered in severe CAP with risk factors or appropriate clinical syndrome doi.org/10.1002/jhm.13…

‼️Did you know that susceptibilities for many PO cephalosporins are inferred from cefazolin, not ceftriaxone? May overcall resistance but safest option if unable to test directly. Removed cefdinir from our adult formulary and switched to cefuroxime. Here’s why! #downwithcefdinir

#IDtwitter Anyone have experience with using pivmecillinam? Surprised to read that it frequently maintains activity amongst esbl and CRE isolates. Recently approved by US FDA. Is there a catch? doi.org/10.1093/ofid/o…

🆕️🔥Systemic review and meta-analysis Ceftazidime-avibactam combination therapy versus monotherapy for treating carbapenem-resistant gram-negative infections #IDXposts link.springer.com/article/10.100…

🔥ORACLE🔥 @yourICM @TrubianoJason A Pilot RCT of Direct Oral Challenge(DOC) vs Routine Care in Low-Risk Penicillin Allergy in Critical Illnes This study supports the safety & efficacy of DOC in low-risk[PEN -FAST< 3] penicillin allergy in ICU #IDXposts link.springer.com/article/10.100…

🆕️⚡️⚡️#JAC Clinical outcomes in patients with pip/tazo-non-susceptible but ceftriaxone-susceptible E. coli or K. pneumoniae bloodstream infection B/w What's the mechanism of resistance for such phenotype? #IDXposts academic.oup.com/jac/article-ab…

🆕️🔥Systematic Review & Meta-analysis 6 retros N:1746 Short Vs. Prolonged Duration of Therapy for Pseudomonas aeruginosa Bacteremia No sig # in 30d mortality Ongoing RCTs 7d Vs 14d: SHORTEN-2 OPTIMISE BALANCE H/t @shorten2trial #IDXposts @BradSpellberg journalofhospitalinfection.com/article/S0195-…

In a retrospective study, there was no difference in outcomes including 30 day mortality between linezolid and clindamycin in GAS infections. #MADID2024 @MAD_ID_ASP @SIDPharm @BaileyGarnerRx

Dr. Thomas Lodise on the efficacy and safety of #cefiderocol in treating critically ill patients with carbapenem-resistant gram-negative bacterial infections. contagionlive.com/view/fetroja-c…

Happy May! 🌼 Incase April was super busy for you, we put together a summary of interesting articles for you to check out. If you have any extra, please let us know in the comments!

Combination of anti-staphylococcal β lactam with standard therapy compared to standard therapy alone for the treatment of MRSA bacteraemia: a post hoc analysis of the CAMERA2 trial using a desirability of outcome ranking (DOOR) approach ✅ Just Accepted bit.ly/3QkiZFy

Another nail in the vancomycin coffin. After accounting for laboratory testing, pharmacist management time, and costs associated with vancomycin associated AKI, daptomycin saved $166 per patient when used in place of vancomycin. academic.oup.com/ofid/advance-a…

Sneak peak of 🆕️🔥 @IDSAInfo/ @ESCMID SAB guidelines 🔆Risk stratification,high or low instead of complicated/uncomplicated 🔆Patients with high-risk features at baseline but TTE & PET/CT are negative, short course 14d Slides shared @seanongwx #ESCMIDGLOBAL2024 Oral Abx?!

ICYMI 🔥 FDA approved an updated label with additional data reinforcing the safety & efficacy profile of Biktarvy® to treat pregnant people with HIV-1 (PWH) with suppressed viral loads🔥 #IDXposts gilead.com/news-and-press…