Cancer Dependency Map Sanger
79 posts

Cancer Dependency Map Sanger
@DepMapSanger

Congratulations to the team. We hope the community find these data useful @DepMapSanger. I'd like to make special mention of the skilled & dedicated scientific technical staff @sangerinstitute and #Procan that make possible generation of these large datasets. @TechsCommit.


Excited to share our paper on identifying genetic vulnerabilities in oral cancer now published in @eLife. For those interested in #CRISPR and #drugdevelopment check elifesciences.org/articles/57761.



Online at @nature: "Repeat expansions confer WRN dependence in microsatellite-unstable cancers" by @nussenza and colleagues. Interesting mechanistic insights into microsatellite instability and the vulnerabilities it confers to #cancer cells nature.com/articles/s4158…

Don't miss this opportunity! Opening for Head of Data Science at Mosaic Therapeutics. Mosaic is a new spin-out from the Sanger using advanced computational methods and next-generation cancer models to find new synthetic-lethal cancer targets. Please RT jobs.sanger.ac.uk/vacancy/head-o…

A huge effort from the team to bring you our cancer organoid derivation and expansion SOP’s. We hope you find them useful @protocolsIO @Garnettlab protocols.io/view/derivatio… protocols.io/view/cryoprese… protocols.io/view/thawing-a… protocols.io/view/derivatio… protocols.io/view/passaging…

N&V by @boehmjesse @broadinstitute on the study by @Garnettlab @sangerinstitute, using the Cancer Dependency Map for drug mechanism‐of‐action investigations --> bit.ly/2OMmFQ9 #CancerGenomics #Genomics #Pharmacogenomics







Hope you can join us for Mathew Garnett's seminar tommorow! The talk will be available online all day with a Q&A at 1pm.


Please come along if you're interested to learn how we're using functional genomics data - including CRISPR screens - to inform multiple aspects of drug discovery including target discovery and drug mechanism of action.

In response to the ongoing #COVID19 pandemic, we will deploy our large-scale genome sequencing platform, alongside regional sequencing centres, to better understand the coronavirus outbreak in the UK bit.ly/2J7XFQC

