Dirk H. Trauner
820 posts

Dirk H. Trauner
@DirkTrauner
Penn Integrates Knowledge Professor, Natural Product Aficionado, Photopharmacologist, Fox Terrierist, and Unfulfilled Architect. #firstgen


A milestone of our photopharmacology ERC project, just up on bioRxiv! Light-dependent control of network activity in human brain tissue of patients with epilepsy &/or brain tumors using lidocaine photoswitches & a novel photocaged propofol. 1/2 biorxiv.org/content/10.648…

Intriguingly, not all photo-drugs showed consistent effects across mouse & human, underscoring the importance of early drug testing in human model systems. Massive joint effort w Christa Müller (Uni Bonn), @DirkTrauner, @HeinzBeck8, & Dept. of Neurosurgery! 2/2






Development of Photoswitchable Cholesterol Derivatives through Side Chain Replacement | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

















