Epigenome Technologies Inc.

Learn about single-cell epigenetic profiling by downloading our guide to single-cell CUT&Tag/Paired-Tag, which provides comparisons to other methods and bioinformatic insight bit.ly/4r7CGRD #Epigenetics #CUTandTag #10XGgenomics #ChIPSeq #SingleCell #PairedTag

Epigenetics Update - Transcription and cohesin direct domain boundary spatial positioning and are linked to Friedreich's ataxia bit.ly/3PBlR3E @AKarnay & Rajan Jain (@PennMedicine, @PennEpiInst) in @MolecularCell #Epigenetics #Chromatin --- epigenometech.com

Epigenetics Update - Functional chromatin signatures premark future lineage-specific enhancers bit.ly/4ffv2RK @julian_pulecio1 & @DanweiHuangfu (@MSKCancerCenter) in @CellGenomics #Epigenetics #Chromatin --- Cancer, immunology, and aging: epigenometech.com

New Epigenome Technologies Blog post! bit.ly/4noAKmm "Single-cell Transcriptomic and Epigenetic Assays Detail the Impact of Aging Throughout the Mouse Brain" Based on a Cell Reports study from Margarita Behrens & Bing Ren #Epigenetics #Blogs #SingleCell #Aging

Epigenetics Update - Selective Elimination of TP53 Mutant Cells by Transcript-Activated Chromatin Shredding bit.ly/4eC7dDr @JingkunZeng and Jennifer A. Doudna in @biorxivpreprint #Epigenetics #Chromatin #Shredding --- epigenometech.com

Epigenetics Update - roX1 and roX2 lncRNAs promote heterochromatinization in intestinal stem cells and impair longevity bit.ly/4txjddb Jian-Quan Ni, Ting Xie, & Fang-Lin Sun in @emboreports #Epigenetics #lncRNA #StemCells --- epigenometech.com

Our expansion of single-cell epigenetics assays continues! Our scCUT&Tag assay is now compatible with the BD Rhapsody platform Learn more here: bit.ly/4lquJDv #Epigenetics #BDrhapsody #CUTandTag #Chromatin #Multiomics #Singlecell #CUTandRUN #ChIPseq #ATACseq

Epigenetics Update - Epigenetic reprogramming of T cell metabolism restores function and enhances anti-tumor immunity in lung cancer go.nature.com/4uJe5nl Yi-Chieh Wu & @hctsaihc in @NatImmunol #Epigenetics #Chromatin #Cancer --- Gan hi-res insight; epigenometech.com

Epigenetics Update - Non-invasive profiling of the tumour microenvironment with spatial ecotypes nature.com/articles/s4158… @aadel_chaudhuri (@MayoClinic) & Aaron M. Newman (@StanfordMed) in @Nature #Epigenetics #Chromatin #TME #Ecotypes --- epigenometech.com

We have recently expanded our single-cell epigenetics assays! Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIP-seq platform Learn more here: bit.ly/4lquJDv #SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq

Epigenetics Update - Transposable elements shape stemness in normal and leukemic hematopoiesis go.nature.com/3OGgLms Giacomo Grillo/@BettinaNadorp and John E. Dick/ @MatLupien (@UHN) in @NatureGenet #Epigenetics #Transposons #Leukemia --- epigenometech.com

Epigenetics Update - Integrated MINFLUX tracking reveals two distinct chromatin dynamics classes across cell types go.nature.com/4nalxVR @Anders_S_Hansen reporting in @NatureSMB #Epigenetics #Chromatin --- Gain deeper insights into gene regulation; epigenometech.com

Learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets #Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers bit.ly/4kgWMF3

Epigenetics News - Powerful tools are revealing the 'control knobs' of the genome go.nature.com/4d3rTBR #Epigenetics #News --- Discover the breakthrough at epigenometech.com

Epigenetics Update - Foxp3 drives context-dependent epigenetic programs that define regulatory T cell molecular identity and function bit.ly/3QLXq3W Yuxi Wei and Shohei Hori (University of Tokyo) in @SciImmunology #Epigenetics #Chromatin --- epigenometech.com

Learn how we used Droplet Paired-Tag to assess RNA expression and his mods in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD #Epigenetics #SingleCell #DropletPairedTag #PairedTag bit.ly/4kgWMF3

Epigenetics Review - Direct roles of long non-coding RNAs in transcription activation go.nature.com/4wnuIqm Juan P. Unfried and @IgorUlitsky (@WeizmannScience) in @NatureSMB #Epigenetics #Chromatin #lncRNAs --- Empower your research at epigenometech.com

Epigenetics Update - eIF4G2-mediated selective translation of chromatin regulators safeguards adult intestinal stem cell identity and differentiation bit.ly/4upG4bm Haruko Kunitomi & Shinya Yamanaka #Epigenetics #Chromatin #StemCells --- epigenometech.com

New Epigenome Technologies Blog! bit.ly/3P6vRBO "An Integrated Epigenetic Analysis of Mouse Brain Aging Reveals Insights into Neurodegeneration" Based on a study from Margarita Behrens and Joseph Ecker in Cell #Epigenetics #Blog #Aging #Neurodegeneration

Epigenetics Update - Glucose-dependent spatial and temporal modulation of oligodendrocyte progenitor cell proliferation via ACLY-regulated histone acetylation go.nature.com/4n14R2X Sami Sauma & Patrizia Casaccia (@CUNY) #Epigenetics #Chromatin --- epigenometech.com