Genetic Engineering & Biotechnology News

Regeneron, Parabilis Ink Up-to-$2.3B Antibody-Peptide Conjugate Collaboration @Regeneron will partner with #ParabilisMedicines to develop an initial five candidates of #ADCs aimed at challenging and historically undruggable targets #antibodies #peptides hubs.li/Q04hjQkz0

How Gut Bacteria Apply Reversible Epigenetic “Bet-Hedging” Strategy to Adapt to Change This epigenetic phase variation mechanism may explain #microbiome resilience and variability and could guide the next generation of #probiotics @gangfang_1 #epigenetics hubs.li/Q04hjvs70

Unlock the power of digital PCR! Join our free GEN webinar on June 18 to explore applications, challenges, and expert insights for research and clinical labs. Register: hubs.li/Q04gZVZ50 #PCR #Genomics #ClinicalLab

Drug Target for Fragile X Syndrome Identified Through Preclinical Study EPAC2 levels appear to rise gradually as the brain matures, suggesting it may be a particularly relevant target for older children and adults with FXS @UCLAHealth #ASD #RNAseq hubs.li/Q04h7_2h0

Organ-on-Chip Method Designed to Zero In on Connection Between Diabetes and Dementia GlucoBrain was established to help researchers understand exactly how diseases like #diabetes and #dementia work at a deeper, biological level @UniofBath #organoids hubs.li/Q04h6-_p0

Accelerate cancer immunotherapy: Discover how experts moved from sequence to patient in under 12 months. Join our free GEN webinar on June 4. Register now: hubs.li/Q04gglbW0 @AsimovBio #CancerImmunotherapy #Sequencing #Biotech #Webinar

Multiomic ALS Study Links Peripheral Immune Infiltration to CNS Inflammation The data shows that #immunecells converge at sites of motor neuron loss and TDP-43 pathology with distinct patterns depending on the #ALS type @NUFeinbergMed #Multiomics hubs.li/Q04g_smh0

Rare Instance of AAV Integration into Human Genome Linked to Brain Tumor Findings support that rare #AAV integration can drive #oncogenesis, underscoring need to refine gene‑delivery methods, monitor transduced tissues post‑treatment @ChildrensPhila hubs.li/Q04g-5VV0

Discover the latest in AAV analytics! Join our free 3-part webinar series on capsid characterization and plasmid DNA control, sponsored by @uspharmacopeia. Register now: hubs.li/Q04gcZx40 #AAV #Genetherapy #Biotech

Operator Protection as Core Design Principle for ADC Bioprocessing ADC manufacturing demands stronger operator protection as potent compounds raise containment and safety challenges #CRBgroup #GENbioprocessing #NextGEN #biomanufacturing hubs.li/Q04gSrfn0

Yeast We Can: Cutting Costs by Optimizing Cell-Free Expression Systems Optimized additive selection could help yeast-based cell-free protein expression systems fulfill their potential at commercial scale @imperialcollege #GENbioprocessing #NextGEN #yeast hubs.li/Q04gSlML0

Adopting Creative Chemistry to Optimize Bioprocessing Workflow Light may damage antibody-drug conjugates during manufacturing; however, novel chemistries help simplify downstream processes @Northeastern #GENbioprocessing #NextGEN #antibodydrugconjugates hubs.li/Q04gSq2r0

Mark Your Calendar! Monoclonal Antibodies: Unlocking Cost and Efficiency Gains in Downstream Processing Register now for this free webinar sponsored by @thermofisher: hubs.ly/Q04dYNR60 #MonoclonalAntibodies #DownstreamProcess

Technique Yields Uniform, High-Quality EVs at Scale MSC-EVs play an outsized role in intracellular communications, influencing such functions as inflammation and tissue repair @SartoriusGlobal #GENbioprocessing #NextGEN #extracellularvesicle hubs.li/Q04gSlPy0

DNA‑Guided CRISPR Suggests a New Direction for RNA Editing “The most meaningful advance is that we show CRISPR‑Cas12 can be reprogrammed to target RNA using a DNA guide rather than an RNA guide,” @JainLaboratory told GEN @UF #CRISPR #RNA #DNA #Cas12 hubs.li/Q04gPNnj0

Cell-free DNA Synthesis of dbDNA™ for a Faster Path to RNA and #DNA Therapeutics Speed is a critical differentiator in therapeutic development. Shortening the design-to-test cycle can be the defining factor in program success. Sponsored by @NEBiolabs hubs.li/Q04gHbLZ0

Top 10 Best-Selling Gene Therapies As more products reach the market, therapy developers partner with researchers and regulators to deliver N-of-1 treatments to patients @AlexWestchester #CRISPR #genetherapy #drugdiscovery hubs.li/Q04gNc4m0

Discover new regulators of NF-κB dynamics! Join our free GEN webinar sponsored by @ElemBio on June 10, 2026. Register now: hubs.li/Q04fVL0F0 #CRISPR #Biotech

ApexGO: AI-Driven Approach to Faster Antibiotic Discovery Researchers at @Penn developed ApexGO, an AI-powered system that optimizes antimicrobial peptides @delafuentelab #antibioticresistance #artificialintelligence #antibiotics hubs.li/Q04gBrxD0

Discover strategies to advance in vivo lentiviral therapies. Tune in as SK pharmteco experts share insights on manufacturing for purity, scalability, and clinical impact. Listen now: hubs.li/Q04dPzW90 #ViralVector #Biotech