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A core microbiome signature as an indicator of health sciencedirect.com/science/articl…
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Liping Zhao
642 posts
Liping Zhao
@Gutzhao
A microbial ecologist with over thirty years of experience on gut ecology. Nutrition, Microbiome and Health; Reference-free and Guild-based Microbiome Analysis.
Katılım Temmuz 2015
2.6K Takip Edilen2.2K Takipçiler
Your gut microbiome is a seesaw for health! 🦠 Fiber-rich diets tip it toward Foundation Guild dominance, promoting weight control and metabolic health. Junk food fuels Pathobionts, driving obesity. #TCGScience #GutHealth
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The Two Competing Guilds (TCG) Model of Core Microbiome
Microbiome Research Reports@MicroResRep
🎙️We interviewed Prof. Liping Zhao (@Gutzhao), Executive Editor of #Microbiome Research Reports and Fellow of the American Academy of Microbiology. 🔗 Watch the full interview: #Microbiome" target="_blank" rel="nofollow noopener">oaepublish.com/interviews/mrr…
#GutHealth #Obesity #MRR #HostMicrobe English
Liping Zhao retweetledi
🎙️We interviewed Prof. Liping Zhao (@Gutzhao), Executive Editor of #Microbiome Research Reports and Fellow of the American Academy of Microbiology.
🔗 Watch the full interview: #Microbiome" target="_blank" rel="nofollow noopener">oaepublish.com/interviews/mrr… #GutHealth #Obesity #MRR #HostMicrobe
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Taxa should no longer be used as entry point analytical units for microbiome datasets. Genomes should be.
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Liping Zhao retweetledi
🎉Huge congratulations to our Editor-in-Chief, Dr. Jizhong Zhou, on being elected to the National Academy of Sciences! This prestigious honor recognizes his outstanding contributions to Microbial Ecology. We are proud and thrilled!
@theNASciences nasonline.org/news/2025-nas-…
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Liping Zhao retweetledi
Researchers, including CIFAR's @Gutzhao, have developed a new method to identify crucial gut microbes essential for health. 🦠
This discovery could lead to precision nutrition and personalized therapies for managing diabetes, IBD and more.
medicalxpress.com/news/2024-10-a…
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Liping Zhao retweetledi
Immensely grateful to all experts who contributed this piece with their expertise and efforts! @nsegata @cibiocm @GiovanniCammar9 @h_sokol @fasnicar @Siew_C_Ng @Gutzhao @PaedsRH @RaesLab @HoldGeorgina @ChristianHvas @KorenLab @TheTunLab @MireiaVallesc @mcarmen_collado @epasolli
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Meet Evo, the DNA-trained AI that creates genomes from scratch | Science | AAAS science.org/content/articl…
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The third pillar of guild-based microbiome data analysis is interaction focused perspective. Co-abundance network analysis of high quality MAGs is used to identify potential guilds jci.org/articles/view/…
Liping Zhao@Gutzhao
The second pillar of guild-based microbiome data analysis is database independence. Each high quality MAG is given a Universal Unique Identifier (UUID) and tracked in samples across different studies for data integration and mining. jci.org/articles/view/…
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The second pillar of guild-based microbiome data analysis is database independence. Each high quality MAG is given a Universal Unique Identifier (UUID) and tracked in samples across different studies for data integration and mining. jci.org/articles/view/…
Liping Zhao@Gutzhao
Guild-based analysis of microbiome data has three pillars, the first is genome-specific analysis with high resolution and granularity than any taxa. High quality metagenome-assembled genomes (MAGs) are the basic features. jci.org/articles/view/…
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Guild-based analysis of microbiome data has three pillars, the first is genome-specific analysis with high resolution and granularity than any taxa. High quality metagenome-assembled genomes (MAGs) are the basic features. jci.org/articles/view/…
Liping Zhao@Gutzhao
What kind of analytical strategy would allow you to integrate 38 different microbiome studies and identify a set of 284 genomes of core bacteria into Two Competing Guilds as an indicator of Health: the guild-based analysis! cell.com/cell/fulltext/…
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What kind of analytical strategy would allow you to integrate 38 different microbiome studies and identify a set of 284 genomes of core bacteria into Two Competing Guilds as an indicator of Health: the guild-based analysis! cell.com/cell/fulltext/…
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Liping Zhao retweetledi
🚨New Paper Alert🚨
Our new #microbiome research, co-led with @LiatShenhav, published today in @CellCellPress!
We show that #breastfeeding "paces" gut & nasal microbiome development to prevent #asthma in the @CHILDSTUDY.
#Tweetorial 🧵
cell.com/cell/fulltext/…
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PG, in contrast, flourishes in low-fiber, calorie-dense conditions, generating pro-inflammatory and endocrine-disrupting metabolites like endotoxins, indole, and hydrogen sulfide. cell.com/cell/fulltext/…
GutMicrobiota Health@GMFHx
Are we ready to define a core microbiome signature as an indicator of health? .@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome: sciencedirect.com/science/articl…
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This concept of stability of relationships as a marker of functional significance is central to understanding the microbiome as a complex adaptive system, where the resilience of microbial networks is directly linked to host health. cell.com/cell/fulltext/…
GutMicrobiota Health@GMFHx
Are we ready to define a core microbiome signature as an indicator of health? .@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome: sciencedirect.com/science/articl…
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In essence, stability within guilds like FG and PG reflects an evolutionary adaptation, enabling the microbiome to sustain functions under environmental pressures that a less connected population could not. cell.com/cell/fulltext/…
GutMicrobiota Health@GMFHx
Are we ready to define a core microbiome signature as an indicator of health? .@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome: sciencedirect.com/science/articl…
English
Restoring and maintaining the TCG structure in the gut microbiome is therefore essential for it to function as a dynamic regulatory interface between the host and the environment. cell.com/cell/fulltext/…
GutMicrobiota Health@GMFHx
Are we ready to define a core microbiome signature as an indicator of health? .@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome: sciencedirect.com/science/articl…
English
It illustrates how dietary choices shift the balance toward either health or dysfunction, suggesting that restoring FG dominance through fiber-rich diets could recalibrate this balance, realigning it with the microbiome’s evolutionary purpose. cell.com/cell/fulltext/…
GutMicrobiota Health@GMFHx
Are we ready to define a core microbiome signature as an indicator of health? .@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome: sciencedirect.com/science/articl…
English
Thus, the stable competition between FG and PG is fundamental to the microbiome’s role as an adaptive nutrient sensor. cell.com/cell/fulltext/…
GutMicrobiota Health@GMFHx
Are we ready to define a core microbiome signature as an indicator of health? .@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome: sciencedirect.com/science/articl…
English