Special thank yous to: @DrEllaOfScience, Pekka Karhunen, Deidre Jansson, Danny Reich, @wysscoray, Dorothy Schafer, David Holtzman, and their labs.
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Lehtinen Lab
351 posts
Lehtinen Lab
@LehtinenLab
basic & translational research on CSF-based signaling & choroid plexus • find us @HMS_Neuro & @BostonChildrens Pathology Dept • // account run by lab members
Boston, MA Katılım Aralık 2019
177 Takip Edilen1.9K Takipçiler
We are grateful to all collaborators for their contributions to the study led by @Huixin_BJ & Peter Lotfy, Benjamin Englert & @JanieOberhauser, and co-senior authors: @ordovas_phd, @liisamyllykang1, @andcyang, and @LehtinenLab.
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New BioRxiv Post‼️
A Multi-Modal atlas combining human pathology, mouse modeling, transcriptomics, and advanced imaging.
Check out the pre-print here: biorxiv.org/content/10.648…
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🌟 Review led by @ScienceYael on apocrine secretion at the choroid plexus: evidence across imaging/proteomics🔬, regulatory cues, and CSF proteome impact
Ya'el Courtney, PhD@ScienceYael
🔬 Calling #CellBiology and #EpithelialCell enthusiasts! My new review article w @LehtinenLab dives into a fascinating, somewhat niche, but critical secretory mechanism by the Choroid Plexus (ChP): apocrine secretion! #citeas" target="_blank" rel="nofollow noopener">link.springer.com/article/10.118…
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New from our lab: in mice, maternal psychedelics reach embryonic CSF within minutes, activate the choroid plexus, and alter development with adult behavior effects. Thread🧵👇
Ya'el Courtney, PhD@ScienceYael
🚨 Psychedelics in pregnancy - can a single dose reach the embryo and matter? Yes. In mice they hit embryonic CSF within minutes, activate choroid plexus→CSF axis, & shift cortical development w adult behavioral signatures. @LehtinenLab Preprint: biorxiv.org/content/10.110… 1/13
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Lehtinen Lab retweetledi
Lehtinen Lab retweetledi
My first journal cover :)
nature.com/neuro/volumes/… Volume 28 Issue 7, July 2025
@NatureNeuro @LehtinenLab
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Funded by @NIH, @NSF, @HHMINEWS, @BostonChildrens, @iddrc_bch, @SimonsFdn Autism Research Initiative, @harvardbrainsci, @NYSCSF, and more! Grateful to the public and private institutions that made this possible.
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HUGE thank you to our collaborators on this project, without whom none of this beautiful work would be possible: Joshua Head, @Freshdipley, @NeilCDani1, Olga Chechneva, @MJHoltzmanlab, @csadegh, and Towia Libermann. @BCH_InTheNews
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Led by @ScienceYael and out today in @NatureNeuro: the brain's fluid-secreting organ — the choroid plexus — can reshape neural development through a powerful, little-known process. & it can be hijacked by serotonergic drugs like LSD. 🧠👇 A thread rdcu.be/eoaSY
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