Dennis Sun

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Dennis Sun

Dennis Sun

@Mezarque

Cofounder of @dittobio, @ycombinator (W26) | prev: @berkeleyMCB @hscrb

Ohlone Land (Berkeley, CA) Katılım Ocak 2012
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Dennis Sun
Dennis Sun@Mezarque·
Some news: excited to share that I'm building @dittobio with @AdairLBorges and @emilycpierce as part of the @ycombinator W26 batch! We're discovering drugs for autoimmune disease by harnessing parasite biology. Shout out @agupta for betting on us. 🔗 below:
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Endura Therapeutics
Endura Therapeutics@EnduraTx·
The genomics revolution told us which genes cause disease. What if small molecules could target the genetic message? CRISPR-level precision, in a pill. Endura Insights #1: why the genomics revolution is only half finished. enduratx.com/blog/the-genom…
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Debesh Mandal
Debesh Mandal@debesh·
Thrilled to announce I have been accepted as a Termeer Fellow (@The_Termeer_Fdn) as part of the Class of 2026. Some very inspiring people involved with this programme so I'm excited to be part of an impactful community of medicine developers.
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Adrian Sanborn
Adrian Sanborn@AdrianSanborn·
I became a scientist watching DNA sequencing reshape biology. Saw the same pattern every time: turn your question into a sequencing readout, and the data drives a revolution. I built a company to bring that to drug discovery, alongside the sharpest people I know. Meet @EnduraTx!
Endura Therapeutics@EnduraTx

The genomics revolution told us which genes cause disease. The next revolution is giving patients a pill that silences those genes. Not a $100K/year biologic requiring regular injections or a $1M gene therapy. A gene-silencing small molecule you can take at home. We're building this at @EnduraTx. Here's how. 🧵

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Dennis Sun
Dennis Sun@Mezarque·
Thrilled to be building with Pioneer!
James Fong@jamesfong

🧬 @dittobio is utilizing parasite strategies for developing breakthrough drugs for autoimmune disease. Why parasites? They've been running experiments on humans for millions of years being able to control the human immune system. Ditto is building an AI platform to identify drug-like proteins from these types of organisms which they then engineer into safe, effective therapeutics. 🦠 🪲 🪱 They are just getting started and have already analyzed over a million proteins across primate-infecting viruses, ticks, and parasitic worms. Initial discovery is looking promising! @pioneer_fund is proud to back these three PhD scientists! Congratulations @AdairLBorges, @Mezarque, and @emilycpierce. Excited to partner with you!

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Dennis Sun
Dennis Sun@Mezarque·
Founder multitasking: - listening to a talk on lipid nanoparticle-mediated immune tolerance… - while stress-buying domain names and emailing cloud providers to kill a spoofed website. At @dittobio we copy nature’s playbook to treat disease. 👯 Today, someone tried copying us.
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Dennis Sun
Dennis Sun@Mezarque·
We highlight how viruses can teach us to find drug targets and even design therapeutic molecules. For example, viruses were the first to invent drugs like Enbrel (etanercept). (green: TNF; orange: etanercept; blue: a viral protein) Reach out if you want to learn more!
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Dennis Sun
Dennis Sun@Mezarque·
It’s been an incredible 10 months of science at @dittobio, and I’m excited to share some of our progress in our first blog post. Today, we're sharing our analysis mapping parasite proteins and human diseases they could treat. dittobio.com/blog/2025-03-0…
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Adair
Adair@AdairLBorges·
Finally got around to writing up some of our progress at @dittobio ! Check out our inaugural blog post to learn how my favorite parasites (aka viruses 😎) can improve target selection and discover blockbuster drug mechanisms for autoimmune disease: dittobio.com/blog/2025-03-0…
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Dennis Sun
Dennis Sun@Mezarque·
I’m representing our team at @dittobio – we copy nature’s playbook to build novel therapeutics for autoimmune diseases. If you’re in Boston and want to meet up, please reach out! I’m excited to talk about platforms, partnerships, and next-gen therapies for autoimmune disease.
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Dennis Sun
Dennis Sun@Mezarque·
My @ycombinator puffer is finally fulfilling its true purpose: keeping me warm in the dead of winter. I’m in Boston this week for the Antigen-Specific Immune Tolerance Summit (as-immunetolerance.com)!
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Dennis Sun
Dennis Sun@Mezarque·
This was my first time attending. Incredible to hear from luminaries in the field and meet many amazing people working hard to bring new therapies to patients in need. Thanks to everyone who reached out for a convo / met up! Follow our work at @dittobio for more :)
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Dennis Sun
Dennis Sun@Mezarque·
China (cont'd): - for US companies to stay competitive, capital efficiency is king - revisions to the regulatory landscape around starting clinical trials (e.g. centralized systems like in AUS/NZ) + improved speed to human evidence could level the playing field 4/n
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Dennis Sun
Dennis Sun@Mezarque·
My top 2 themes from this year's @Biocom Global Partnering & Investor Conference #BiocomGPIC: 1. AI's impact in drug discovery + development 2. China <> US competition & collaboration Every panel conversation kept returning to these two areas. More in thread: 1/n
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Dennis Sun
Dennis Sun@Mezarque·
Looking forward to great conversations around platform biotech, partnerships, and new collaborations. If you’re attending, please reach out! Would love to grab coffee and catch up.
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Dennis Sun
Dennis Sun@Mezarque·
Excited to be back home in sunny San Diego for @Biocom's Global Partnering & Investor Conference this week. hashtag #BiocomGPIC I’m here representing our team at @dittobio, where we’re copying nature’s playbook to build next-gen protein therapeutics for autoimmune disease.
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Dennis Sun
Dennis Sun@Mezarque·
Vapid, grifting, rage bait-driven startups do a disservice to the broader ecosystem b/c the public (+ media class) over-indexes on stories like these. Most founders I know are good, kind, serious people trying to solve real problems. A shame the grifters get outsized attention
Harper's Magazine@Harpers

“Until we build an all-powerful but distant God, the agency problem remains. AIs are not capable of directing themselves; most people aren’t either.” Sam Kriss reports from San Francisco on the next generation of AI technologists. harpers.org/archive/2026/0…

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Keşfet

@debesh @The_Termeer_Fdn @AdrianSanborn @EnduraTx @posthog @GoDaddy @AWSstartups @googlecloud